Integrating heterogeneous biomedical data, including clinical metadata, histopathology images, and molecular profiles, is crucial for comprehensive disease understanding. However, gene expression data acquisition remains constrained by high costs and privacy concerns, limiting its use in multimodal research and AI-driven applications.
arXiv:2608.28787v1 Announce Type: new
Abstract: Joint-embedding predictive architectures (JEPAs) have primarily been developed for self-supervised representation learning. Denoising JEPA (D-JEPA) rec...
By Meng Zhou, Wenhao You, Yuxing Chen, Yueying Tian
The paper introduces StyleGANCA, a lightweight neural cellular automata (NCA) based generative adversarial network designed for medical image synthesis. By combining a StyleGAN-inspired mapping network with adaptive style modulation in a multi-scale NCA framework, the model achieves high-quality image generation with far fewer parameters than existing adversarial, variational, diffusion, and NCA baselines. Experiments on BloodMNIST and PathMNIST show competitive FID and KID scores, and the synthetic images preserve class-specific information, effectively supporting downstream multi-class classifier training.
By Anh Thi Luu, Nick Lemke, Anirban Mukhopadhyay
arXiv:2608. 13256v1 Announce Type: cross Abstract: As biomedical research increasingly relies on data-intensive tools, the quality and utility of datasets are critical.
By Francesca Pia Panaccione, Sofia Mongardi, Marco Masseroli, Pietro Pinoli
SynerMedGen is a unified framework that aligns medical multimodal understanding with generation tasks through task alignment. It introduces three generation‑aligned understanding tasks and a two‑stage training strategy that transfers representations learned during understanding to medical image synthesis. The model achieves strong zero‑shot performance on 22 synthesis tasks and outperforms state‑of‑the‑art specialized and unified models when combined with generation training, supported by a new 1M‑sample SynerMed dataset.
By Weiren Zhao, Yi Dong, Cheng Chen
arXiv:2510.06113v2 Announce Type: replace
Abstract: Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which red...
By Shuo Jiang, Zhuwen Chen, Liaoman Xu, Yanming Zhu, Changmiao Wang, Jiong Zhang, Feiwei Qin, Yifei Chen, Zhu Zhu
arXiv:2609.25088v1 Announce Type: cross
Abstract: Survival prediction for glioblastoma multiforme (GBM) demands models that are both accurate and interpretable, yet existing approaches treat these ob...
By Mushahid Intesum
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
By Jingyu Hu, Giuseppe Tripodi, Reed Naidoo, Sarah F. McGough, Tapabrata Chakraborti
The paper introduces SMILE, a self‑explainable multimodal information bottleneck framework for medical diagnosis. It jointly optimizes predictive accuracy and modality‑specific explainability by selecting the most informative elements within each data modality. Experiments on diverse medical datasets show strong diagnostic performance, including a 9.1‑percentage‑point accuracy gain on the iCTCF dataset, and provide transparent, modality‑aware explanations that enhance both explainability and generalization.
By Yuqing Yang, Alexander Schmatz, Zhaozhao Ma, Changkyu Choi, Robert Jenssen, Shujian Yu
LatentVerse is a new framework that provides a web-based visual analytics platform and a command-line interface for analyzing multimodal latent representations. It unifies diagnostics for representation quality metrics and extends analysis to multimodal settings by decomposing embeddings into shared and modality-specific components. The authors evaluate the tool through simulations, real biomedical data analyses, and a user study, demonstrating its utility for interpretable evaluation of foundation model representations.
By Majd Alafrange, Samuel Friedman, John Kitonyo, Sana Tonekaboni, Mahnaz Maddah
arXiv:2606. 07640v1 Announce Type: cross Abstract: This study investigates the trade-offs between fidelity, privacy, and utility in synthetic data generation under conditions of data scarcity and privacy sensitivity.
By Borja Arroyo Galende, Alejandro Almod\'ovar, Patricia A. Apell\'aniz, Juan Parras, Silvia Uribe, Santiago Zazo
arXiv:2606. 17989v1 Announce Type: cross Abstract: Multi-contrast magnetic resonance imaging (MRI) provides complementary information for clinical diagnosis.
By Yonghao Chen, Sicheng Yang, Rui Tang, Lei Zhu