Integrating heterogeneous biomedical data, including clinical metadata, histopathology images, and molecular profiles, is crucial for comprehensive disease understanding. However, gene expression data acquisition remains constrained by high costs and privacy concerns, limiting its use in multimodal research and AI-driven applications.
arXiv:2608. 13256v1 Announce Type: cross Abstract: As biomedical research increasingly relies on data-intensive tools, the quality and utility of datasets are critical.
By Francesca Pia Panaccione, Sofia Mongardi, Marco Masseroli, Pietro Pinoli
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
By Jingyu Hu, Giuseppe Tripodi, Reed Naidoo, Sarah F. McGough, Tapabrata Chakraborti
arXiv:2606. 07640v1 Announce Type: cross Abstract: This study investigates the trade-offs between fidelity, privacy, and utility in synthetic data generation under conditions of data scarcity and privacy sensitivity.
By Borja Arroyo Galende, Alejandro Almod\'ovar, Patricia A. Apell\'aniz, Juan Parras, Silvia Uribe, Santiago Zazo
arXiv:2606. 17989v1 Announce Type: cross Abstract: Multi-contrast magnetic resonance imaging (MRI) provides complementary information for clinical diagnosis.
By Yonghao Chen, Sicheng Yang, Rui Tang, Lei Zhu
arXiv:2505. 06945v5 Announce Type: replace Abstract: Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records.
By Maryam Farhadizadeh, Maria Weymann, Michael Bla{\ss}, Johann Kraus, Christopher Gundler, Sebastian Walter, Noah Hempen, Hannah Bast, Harald Binder, Nadine Binder
arXiv:2606. 24430v1 Announce Type: cross Abstract: Training of neural networks for histopathology classification tasks typically relies on data encoding into latent space, which reduces complexity and improves performance.
By Christian Z\"ollner (Department of Applied Tumor Biology Institute of Pathology Heidelberg University Hospital), Mozzam Motiwala (Department of Applied Tumor Biology Institute of Pathology Heidelberg University Hospital), Aysel Ahadova (Department of Applied Tumor Biology Institute of Pathology Heidelberg University Hospital), Gerrit Anders (Leibniz Institut f\"ur Wissensmedien), Robert H\"uneburg (National Center for Hereditary Tumor Syndromes University Hospital Bonn, Department of Internal Medicine I University Hospital Bonn), Jacob Nattermann (National Center for Hereditary Tumor Syndromes University Hospital Bonn, Department of Internal Medicine I University Hospital Bonn), Matthias Kloor (Department of Applied Tumor Biology Institute of Pathology Heidelberg University Hospital)
arXiv:2606. 19651v1 Announce Type: new Abstract: Three-dimensional (3D) brain MRI is central to clinical neurology and neuro-oncology, where generative models could augment under-represented cohorts, simulate disease trajectories, and support privacy-preserving data sharing.
By Max Van Puyvelde, Ibrahim Gulluk, Wim Van Criekinge, Olivier Gevaert
arXiv:2607. 07673v1 Announce Type: cross Abstract: Medicine is inherently multimodal, requiring clinicians to synthesize information across diverse data streams.
By Hyunjae Kim, Dain Kim, Pan Xiao, Serina S. Applebaum, Younjoon Chung, Xuguang Ai, Yu Yin, Roy Jiang, Yuexi Du, Yawen Wei, Yiming Kong, Tuo Guo, Zhiyuan Cao, Mengmeng Du, Yuelei Fu, Yan Hu, Rui Shi, Gui Yang, Kevin W. Jin, Yuntian Liu, Yuxuan Tian, Jonathan Marquez, Zhen Chen, Sheng Zhang, Hoifung Poon, Hua Xu, Jaewoo Kang, Qingyu Chen
arXiv:2607. 18882v1 Announce Type: cross Abstract: Validating Explainable Artificial Intelligence (XAI) methods in medical imaging requires ground-truth data with known locations of informative features.
By Rick Wilming, Irem Ozseker, Luca Matteo Cornils, Ahc\`ene Boubekki, Benedict Clark, Danny Panknin, Stefan Haufe
arXiv:2607. 01656v1 Announce Type: new Abstract: The interaction between brain structure and genetic influences is key to understanding neuropsychiatric disorders.
By Jueqi Wang, Zachary Jacokes, John Darrell Van Horn, Kevin A. Pelphrey, Michael C. Schatz, Archana Venkataraman
arXiv:2607. 20557v1 Announce Type: cross Abstract: Scientific discovery is increasingly shifting from isolated disciplines to multi-domain reasoning, and AI for science faces a similar transition.
By Hesen Chen, Xinyu Su, Xiaomeng Yang, Yuetan Lin, Zixiong Yang, Junyi An, Fenglei Cao, Yifeng Jiao, Yunqi Zhang, Yuan Cheng, Zhiyu Tan, Hao Li, Libo Wu, Yuan Qi