The paper introduces SMILE, a self‑explainable multimodal information bottleneck framework for medical diagnosis. It jointly optimizes predictive accuracy and modality‑specific explainability by selecting the most informative elements within each data modality. Experiments on diverse medical datasets show strong diagnostic performance, including a 9.1‑percentage‑point accuracy gain on the iCTCF dataset, and provide transparent, modality‑aware explanations that enhance both explainability and generalization.
arXiv:2607. 09982v1 Announce Type: new Abstract: Electronic health record (EHR) data are inherently multimodal, and leveraging multiple modalities can improve predictive performance.
arXiv:2605. 22547v3 Announce Type: replace-cross Abstract: Medical image diagnosis has achieved significant progress with deep learning, yet existing methods often rely on isolated visual evidence and lack the ability to effectively leverage similar cases and external knowledge.
arXiv:2403. 14926v3 Announce Type: replace-cross Abstract: Electronic health record (EHR) systems capture a wealth of multimodal clinical data, encompassing both structured clinical codes and unstructured clinical notes.
arXiv:2607. 25933v1 Announce Type: cross Abstract: Clinical diagnostic evaluation should not only assess whether models can provide correct diagnoses, but also reflect the realities of clinical practice, including progressive disclosure of multimodal information, dynamic updating of diagnostic hypotheses, and continuous refinement of clinical reasoning.
arXiv:2608. 02692v1 Announce Type: new Abstract: Access to holistic, multimodal data improves the performance of Artificial Intelligence (AI) in medical classification tasks compared to utilizing single modalities or data sources.
arXiv:2604. 16878v2 Announce Type: replace Abstract: Early prediction of severe clinical deterioration and remaining length of stay can enable timely intervention and better resource allocation in high-acuity settings such as the ICU.
arXiv:2205. 04599v2 Announce Type: replace-cross Abstract: Explainable Artificial Intelligence (XAI) is essential for trustworthy AI in healthcare, yet many existing methods rely on technical explanations that are difficult for clinicians and patients to interpret.
arXiv:2501. 16106v2 Announce Type: replace Abstract: Recent advances in multimodal depression recognition for clinical interviews (MDRC) have demonstrated the potential of AI systems by integrating textual, acoustic, and facial cues.
arXiv:2608.22323v1 Announce Type: new Abstract: The application of Large Language Models (LLMs) to diagnostic decision-making has garnered growing interest. However, existing benchmarks largely focus...
ICON Decomposition is a new method for explaining deep neural networks by quantifying how much variance each concept explains in a network layer after accounting for all other concepts and the outcome. Unlike previous concept‑based methods that evaluate concepts in isolation, ICON can distinguish genuine model reliance from spurious correlations. Experiments on synthetic data, skin‑lesion, and brain‑imaging models show that ICON recovers concept importance more accurately, isolates truly relied‑upon concepts, and provides sparse explanations validated through retraining and out‑of‑distribution testing.
Integrating heterogeneous biomedical data, including clinical metadata, histopathology images, and molecular profiles, is crucial for comprehensive disease understanding. However, gene expression data acquisition remains constrained by high costs and privacy concerns, limiting its use in multimodal research and AI-driven applications.
arXiv:2606. 25606v1 Announce Type: cross Abstract: Given the widespread prevalence of depression and its consequential impact on individuals and society, it is crucial to obtain objective measures for early diagnosis and intervention.