arXiv AI

GigaPath-Flash and GigaTIME-Flash: Efficient Pathology Foundation Models for Whole-Slide and Tumor Microenvironment Analysis

arXiv:2607. 18218v1 Announce Type: cross Abstract: Foundation models have emerged as a driving force in computational pathology, with the potential to transform cancer diagnosis, prognosis, and treatment selection by learning transferable representations from large-scale histopathology data.

arXiv AI
Jun 8

DaX: Learning General Pathology Representations Across Scales

arXiv:2606. 06983v1 Announce Type: cross Abstract: Computational pathology requires visual representations that transfer across diverse clinical endpoints and remain robust to variation in magnification, staining, scanner type, slide preparation, and input resolution.

By Bokai Zhao, Yiyang Zhang, Long Bai, Tai Ma, Hanqing Chao, Minfeng Xu
arXiv AI
Jun 30

Data-Efficient Multimodal Alignment for Histopathology-based Molecular Prediction

arXiv:2606. 29949v1 Announce Type: cross Abstract: H&E-stained whole-slide images offer cohort-scale availability and rich spatial context but lack molecular specificity, whereas bulk RNA-seq provides transcriptome-wide resolution at high cost with limited archival availability.

By Dominik Winter, Dominik Vonficht, Lo\"ic Le Bescond, Christian Gebbe, Marco Rosati, Richard J. Chen, Markus Schick, Ross Stewart, Nicolas Brieu
arXiv AI
Jun 17

SegTME-UNI2: A Foundation Model-Based Framework for Generalisable Multiclass Cell Segmentation and LLM-Driven Tumour Microenvironment Characterisation in Histopathology

arXiv:2606. 17702v1 Announce Type: cross Abstract: Characterising the tumour microenvironment (TME) from routine H&E-stained histology images requires simultaneous cell segmentation, feature extraction, and interpretable clinical reporting.

By Wan Siti Halimatul Munirah Wan Ahmad, Faris Syahmi Samidi, Mohammad Badal Ahmmed, Vimal Angela Thiviyanathan, Selvam James Thavaraj, Anwar P. P. Abdul Majeed
arXiv AI
Jun 11

Atlas H&E-TME: Scalable AI-Based Tissue Profiling at Expert Pathologist-Level Accuracy

arXiv:2606. 12346v1 Announce Type: cross Abstract: Hematoxylin and eosin (H&E) staining is the cornerstone of histopathology, yet scalable, quantitative analysis of H&E whole-slide images (WSIs) remains a central challenge in computational pathology.

By Kai Standvoss, Miriam H\"agele, Rosemarie Krupar, Julika Ribbat-Idel, Jennifer Altsch\"uler, Gerrit Erdmann, Hans Pinckaers, Evelyn Ramberger, Madleen Drinkwitz, \'Ad\'am N\'arai, Alexander M\"ollers, Katja Lingelbach, Sebastian Kons, Lukas H\"onig, Recepcan Adig\"uzel, Joana Bai\~ao, Alberto Megina Gonzalo, Marius Teodorescu, Marie-Lisa Eich, Paolo Chetta, Shakil Merchant, Verena Aumiller, Simon Schallenberg, Andrew Norgan, Klaus-Robert M\"uller, Lukas Ruff, Maximilian Alber, Frederick Klauschen
arXiv AI
Aug 11

Simple Token-Efficient Vision-Language Model for Case-level Pathology Synoptic Report Generation

arXiv:2605. 30716v2 Announce Type: replace-cross Abstract: Generating clinically useful pathology reports for pathology cases from whole-slide images (WSIs) is challenging due to gigapixel resolution, long visual-token sequences, and the complexity of case-level reasoning, where a single case may contain multiple WSIs with heterogeneous tissues and ambiguous findings.

By Zhiyuan Yang, Jiahao Cheng, Vincent Quoc-Huy Trinh, Mahdi S. Hosseini
arXiv AI
Jul 13

ALICE: Learning a General-Purpose Pathology Foundation Model from Vision, Vision-Language, and Slide-Level Experts

arXiv:2607. 09526v1 Announce Type: cross Abstract: Foundation models are reshaping computational pathology, yet their capabilities remain shaped by pretraining objectives, data sources, and spatial scales, fragmenting complementary expertise across separate backbones.

By Jiawen Li, Tian Guan, Huijuan Shi, Xitong Ling, Mingxi Fu, Anjia Han, Chao He, Yonghong He
arXiv Machine Learning
Aug 11

TRAPS: Treatment-Assignment Prediction via Pathway-informed Stratification

arXiv:2606. 09898v2 Announce Type: replace Abstract: Cancer treatment involves decisions across multiple clinical outcomes, yet pathway-informed deep learning models are typically evaluated in isolation, making their relative benefits unclear.

By Sujoy Banik, Sayantan Chakraborty, Boishakhi Das Toma, Zainab Ghafoor, Ushashi Bhattacharjee, Koushik Howlader, Tirtho Roy
arXiv AI
Aug 5

A Deployment-Friendly Foundational Framework for Efficient Computational Pathology

arXiv:2602. 14010v2 Announce Type: replace-cross Abstract: Pathology foundation models (PFMs) generalize well across computational pathology tasks but remain costly for gigapixel whole-slide image analysis.

By Yu Cai, Cheng Jin, Zhengyu Zhang, Jiabo Ma, Fengtao Zhou, Yingxue Xu, Zhengrui Guo, Yihui Wang, Zhengyu Zhang, Ling Liang, Yonghao Tan, Pingcheng Dong, Du Cai, On Ki Tang, Chenglong Zhao, Zhijian Cen, Ying Tan, Xi Wang, Can Yang, Yali Xu, Jing Cui, Zhenhui Li, Ronald Cheong Kin Chan, Yueping Liu, Feng Gao, Xiuming Zhang, Li Liang, Hao Chen, Kwang-Ting Cheng