arXiv Computation and Language

SLICEChat: Progressive In-Encoder Token Pruning for Whole-Slide Pathology Language Models

arXiv AI
Aug 11

Simple Token-Efficient Vision-Language Model for Case-level Pathology Synoptic Report Generation

arXiv:2605. 30716v2 Announce Type: replace-cross Abstract: Generating clinically useful pathology reports for pathology cases from whole-slide images (WSIs) is challenging due to gigapixel resolution, long visual-token sequences, and the complexity of case-level reasoning, where a single case may contain multiple WSIs with heterogeneous tissues and ambiguous findings.

By Zhiyuan Yang, Jiahao Cheng, Vincent Quoc-Huy Trinh, Mahdi S. Hosseini
arXiv Computer Vision
Aug 25

LanGuSTE: Language-Guided Coarse-to-Fine Patch Selection for Efficient Whole Slide Image Analysis

LanGuSTE is a patch‑selection framework for whole slide image analysis that uses vision‑language models and large language model knowledge. It introduces Cross‑Scale Visual Prompt Tuning to align low‑resolution and high‑resolution patches, and a coarse‑to‑fine selection module that encodes only informative high‑resolution patches. Experiments show LanGuSTE cuts overall processing time to about one‑third of the baseline while matching or surpassing diagnostic performance of exhaustive and state‑of‑the‑art methods.

By Yonghan Shin, Gangsu Kim, Won-Ki Jeong
Hugging Face Trending Papers
Jul 26

PathSelect: Sequential Token Selection for Whole Slide Pathology

Gigapixel Whole-Slide Images (WSIs) present a fundamental computational bottleneck for vision-language models (VLMs) due to extreme sequence lengths. Existing approaches predominantly rely on spatial sampling or training-free pruning, which risk diluting weak but informative signals, leading to the loss of critical diagnostic evidence due to the spatially diffuse nature of pathological cues.

arXiv AI
Jun 26

MedPruner: Training-Free Hierarchical Token Pruning for Efficient 3D Medical Image Understanding in Vision-Language Models

arXiv:2603. 11625v2 Announce Type: replace-cross Abstract: While specialized Medical Vision-Language Models (VLMs) have achieved remarkable success in interpreting 2D and 3D medical modalities, their deployment for 3D volumetric data remains constrained by significant computational inefficiencies.

By Shengyuan Liu, Zanting Ye, Yunrui Lin, Chen Hu, Wanting Geng, Xu Han, Bulat Ibragimov, Yefeng Zheng, Yixuan Yuan
arXiv Computer Vision
4d ago

Exploiting Spatial Structure for Transductive Few-Shot Classification of Whole-Slide Images

The paper introduces SlideTIM, a transductive few‑shot classification method tailored for whole‑slide images (WSIs). SlideTIM extends the LC‑TIM approach by adding a spatial‑latent regularizer and a class‑distribution prior, ensuring that spatially and semantically similar patches receive consistent predictions and that predicted class proportions are calibrated. Experiments on four histology datasets show that SlideTIM outperforms existing TIM variants, boosting macro‑F1 scores by up to 8.1 percentage points over the best baseline and 19.4 percentage points over zero‑shot predictions at one shot.

By Tiffanie Godelaine, Manon Dausort, Karim El Khoury, Beno\^it G\'erin, Beno\^it Macq, Christophe De Vleeschouwer
arXiv AI
Jul 21

GigaPath-Flash and GigaTIME-Flash: Efficient Pathology Foundation Models for Whole-Slide and Tumor Microenvironment Analysis

arXiv:2607. 18218v1 Announce Type: cross Abstract: Foundation models have emerged as a driving force in computational pathology, with the potential to transform cancer diagnosis, prognosis, and treatment selection by learning transferable representations from large-scale histopathology data.

By Naoto Usuyama, Jeya Maria Jose Valanarasu, Sicong Yao, Hanwen Xu, Jaspreet Bagga, Guanghui Qin, Robert E. Kramer, Cliff Wong, Soohee Lee, Hao Qiu, Theodore Zhengde Zhao, Racheli Ben Shimol, Angela Crabtree, Kevin Matlock, Eduardo Alejandro Lozano Garcia, Naiteek Sangani, Alberto Santamaria-Pang, Jason Entenmann, Alexandra Q. Bartlett, Bill J. Wright, Bernard A. Fox, Brian Piening, Sheng Zhang, Sheng Wang, Tristan Naumann, Carlo Bifulco, Hoifung Poon
arXiv AI
Sep 2

Benchmarking Vision-Language Models for Automated Pathology Diagnosis and Report Generation

arXiv:2609.00866v1 Announce Type: cross Abstract: The rapid advancement of vision-language models (VLMs) has accelerated progress in computational pathology; however, whole-slide image (WSI)-based pa...

By Yumi Lee, Harim Oh, Hyoryung Kim, Minji Kim, Eunsu Kim, Hyeseong Lee, Junya Fukuoka, Andrey Bychkov, Jijgee Munkhdelger, Rajiv Kumar Kaushal, Ayushi Sahay, Rajni Yadav, Bharathi Prabakaran, Sulen Sarioglu, Serdar Balc{\i}, Ilknur Turkmen, Yuri Tolkach, Christian Harder, Julian Westerdorf, Reinhard Buettner, Audun Ljone Henriksen, Sepp De Raedt, Byung Hyun Lee, Sungjin Lim, Joohoon Lee, Gwanghyun Kim, Se Young Chun, Suryakant Singh, Saarthak Kapse, Prateek Prasanna, Kyung A Kim, Yousun Kang, Sehwan Yoo, Sungman Hong, Shubham Innani, Michael Feldman, Spyridon Bakas, Ujjwal Baid, Prasad Dutande, Suhas Gajare, Bhakti Baheti, Serkan S\"okmen, Ece Tu\u{g}ba Cebeci, Ahmet Hal{\i}c{\i}, Musa Balc{\i}, Kardelen Pe\c{c}enek, Srividhya Sainath, Kyongseok Jang, Messi H. J. Lee, Noorul Wahab, Bodong Du, Jiaming Zhang, Qixiang Zhang, Jang-Hwan Choi, Sangjeong Ahn
arXiv AI
Sep 2

SlideBank: A Persistent Hierarchical Evidence Bank for Consistent Whole-Slide Reasoning

SlideBank is a training‑free framework that turns each whole‑slide image into a persistent, concept‑indexed evidence bank. It performs coarse‑to‑fine exploration to locate informative regions and multi‑scale views, converts them into explicit morphological observations, and anchors pathology signals to the supporting patches and slide coordinates. During inference, questions are routed to relevant signals and evidence scales, and a confidence‑based cross‑level consensus integrates global, regional, and patch evidence, achieving high accuracy on WSI‑VQA and SlideBench‑BCNB while enabling consistent re‑phrasing and reduced inference cost.

By Beidi Zhao, Gexin Huang, Ciro Zhang, Anqi Li, Yusheng Tan, Chen Zhou, Gang Wang, Zu-hua Gao, Xiaoxiao Li
arXiv AI
Sep 10

Semantic Context-aware mOdality fUsion Transformer (SCOUT): A Context-Aware Multimodal Transformer for Concept-Grounded Pathology Report Generation

SCOUT is a concept‑grounded multimodal transformer that generates whole‑slide pathology reports by integrating local histological patterns, whole‑slide context, and expert‑curated diagnostic concepts. It uses evolving visual representations and recursively updated slide‑ and concept‑conditioned representations, with separate attention pathways during decoding that are fused adaptively for each token. Evaluated on TCGA‑BRCA, HistAI, and REG‑2025, SCOUT outperformed existing methods, improving BLEU, METEOR, and ROUGE‑L scores and raising the Clinical Report Quality Score on REG‑2025.

By Suryakant Singh, Saarthak Kapse, Joel Saltz, Prateek Prasanna