FlowMoDL is an unrolled neural network designed for highly accelerated 4D flow MRI reconstruction, optimizing both anatomical magnitude and phase-derived velocity accuracy. It alternates a learned (3+1)D spatiotemporal denoiser with conjugate‑gradient data‑consistency updates, using a dual‑pathway conditioning scheme to handle acceleration factors from 10× to 50×. Trained with a deep‑supervision composite loss that penalizes velocity magnitude and angular errors, FlowMoDL outperforms classical and deep‑learning baselines on the multi‑center CMRx4DFlow dataset, achieving superior gradient‑step efficiency and robust convergence across all acceleration factors.
By Tristan Gottwald, Michelle Bruch, Mubashir-Ul Hassan, Fatma Alickovic, Milan Kloiber, Daniel Tenbrinck, Torsten Panholzer, Melanie Schaller, Jana Hutter
arXiv:2606. 06313v1 Announce Type: cross Abstract: Wall shear stress (WSS) governs near-wall transport dynamics and is a key hemodynamic indicator in cardiovascular flows, yet remains difficult to infer accurately due to the need for precise computation of near-wall velocity gradients.
By Mahmoud Elhadidy, Siva Viknesh, Roshan M. D'Souza, Amirhossein Arzani
The study presents a multimodal BrainAGE framework that fuses structural T1-weighted MRI with DeepCBV maps—vascular information synthesized from non‑contrast MRI—to estimate brain age more accurately. Using two separate 3D convolutional neural networks, the combined model achieved a mean absolute error of 3.95 years on cognitively normal controls, outperforming single‑modality models. Saliency analyses showed MRI highlighted white matter and cortical atrophy, while DeepCBV emphasized vascular‑rich regions, and the integrated approach revealed stronger differentiation between stable and progressive MCI, indicating sensitivity to early vascular changes.
By Jordan Jomsky, Zongyu Li, Kay C. Igwe, Yiren Zhang, Max Lashley, Tal Nuriel, Andrew Laine, Scott A. Small, Jia Guo, for the Frontotemporal Lobar Degeneration Neuroimaging Initiative, for the Alzheimer's Disease Neuroimaging Initiative
X‑LMC is a spatiotemporal deep‑learning framework that automatically scores leptomeningeal collateral (LMC) status from time‑resolved biplane digital subtraction angiography (DSA). It uses a DINOv2 backbone to encode spatial frames, a token‑level cross‑view attention module to fuse orthogonal projections, and a recurrent network to model contrast bolus dynamics. On a multicenter dataset of 134 M1‑segment occlusion patients, X‑LMC achieved a Quadratic Weighted Kappa of 0.398 and a macro‑F1 of 0.711, outperforming static and other spatiotemporal baselines and matching clinical inter‑rater agreement.
arXiv:2608.30975v1 Announce Type: cross
Abstract: Cardiac magnetic resonance imaging (CMR) produces rich sequential data such as temporal cine videos and spatial LGE/mapping stacks, yet most deep lea...
By Athira J. Jacob, Puneet Sharma, Dorin Comaniciu, Daniel Rueckert
The study presents a fully automated 4D U‑Net that segments the ascending aorta, arch, and proximal descending aorta in 4D flow MRI using a hybrid 4D convolutional kernel and sparse 4D labels derived from 2D expert contours and centerlines. Trained on 268 scans from eight centers, the model achieved high Dice scores (0.927 internal, 0.911 external) and excellent agreement with expert measurements of peak velocity, net flow, wall shear stress, and diameters (ICC ≥0.954 internal, ≥0.980 external). Compared to frame‑wise 3D networks and semi‑automatic methods, the 4D U‑Net outperformed in diastole and generalised well to independent post‑contrast data.
By Hinrich Rahlfs, Julio Garcia, Chiara Manini, Markus H\"ullebrand, Sebastian Schmitter, Sarah Nordmeyer, Titus K\"uhne, Heiko Stern, Christian Meierhofer, Andreas Harloff, Sebastian Kelle, Alexander Lenz, Peter Bannas, Jeanette Schulz-Menger, Ralf F Trauzeddel, Anja Hennemuth
arXiv:2609.15550v1 Announce Type: cross
Abstract: X-ray coronary angiography is the clinical gold standard for coronary artery disease during real-time cardiac interventions, but provides only 2D pro...
By Deyu Meng, Mojtaba Lashgari, Yiying Wang, Abhirup Banerjee
arXiv:2605. 08832v3 Announce Type: replace Abstract: Neural surrogate models for computational fluid dynamics (CFD) are typically trained as forward operators that map explicit problem specifications, such as geometry and boundary conditions, to solution fields.
By Jonas Weidner, Yeray Martin-Ruisanchez, Daniel Rueckert, Benedikt Wiestler, Julian Suk
arXiv:2606. 26764v1 Announce Type: cross Abstract: Developing robust artificial intelligence models for 4D (3D + time) medical imaging is constrained by limited annotated data, inter-device domain shifts, and privacy restrictions.
By Yiheng Cao, Gustavo Andrade-Miranda, Jiatian Zhang, Lingxiao Zhao, Xin Gao
Developing robust artificial intelligence models for 4D (3D + time) medical imaging is constrained by limited annotated data, inter-device domain shifts, and privacy restrictions. To address this, we propose a 4D controllable generative framework for anatomically consistent data augmentation.
arXiv:2312. 17670v5 Announce Type: replace-cross Abstract: The Circle of Willis (CoW) is an important network of arteries connecting major circulations of the brain.
By Kaiyuan Yang, Fabio Musio, Yihui Ma, Norman Juchler, Johannes C. Paetzold, Rami Al-Maskari, Luciano H\"oher, Hongwei Bran Li, Ibrahim Ethem Hamamci, Anjany Sekuboyina, Suprosanna Shit, Houjing Huang, Chinmay Prabhakar, Ezequiel de la Rosa, Bastian Wittmann, Diana Waldmannstetter, Florian Kofler, Fernando Navarro, Martin J. Menten, Ivan Ezhov, Daniel Rueckert, Iris N. Vos, Ynte M. Ruigrok, Birgitta K. Velthuis, Hugo J. Kuijf, Pengcheng Shi, Wei Liu, Ting Ma, Maximilian R. Rokuss, Yannick Kirchhoff, Fabian Isensee, Klaus Maier-Hein, Chengcheng Zhu, Huilin Zhao, Philippe Bijlenga, Julien H\"ammerli, Catherine Wurster, Laura Westphal, Jeroen Bisschop, Elisa Colombo, Hakim Baazaoui, Hannah-Lea Handelsmann, Andrew Makmur, James Hallinan, Amrish Soundararajan, Benedikt Wiestler, Jan S. Kirschke, Evamaria O. Riedel, Roland Wiest, Emmanuel Montagnon, Laurent Letourneau-Guillon, Kwanseok Oh, Dahye Lee, Orhun Utku Aydin, Adam Hilbert, Jana Rieger, Dimitrios Rallios, Satoru Tanioka, Alexander Koch, Dietmar Frey, Abdul Qayyum, Moona Mazher, Steven Niederer, Nico Disch, Julius C. Holzschuh, Dominic LaBella, Francesco Galati, Daniele Falcetta, Maria A. Zuluaga, Chaolong Lin, Haoran Zhao, Zehan Zhang, Minghui Zhang, Xin You, Hanxiao Zhang, Guang-Zhong Yang, Yun Gu, Sinyoung Ra, Jongyun Hwang, Hyunjin Park, Junqiang Chen, Marek Wodzinski, Henning M\"uller, Nesrin Mansouri, Florent Autrusseau, Cansu Yalcin, Rachika E. Hamadache, Clara Lisazo, Joaquim Salvi, Adri\`a Casamitjana, Xavier Llad\'o, Uma Maria Lal-Trehan Estrada, Valeriia Abramova, Luca Giancardo, Arnau Oliver, Paula Casademunt, Adrian Galdran, Matteo Delucchi, Oscar Camara, Jialu Liu, Haibin Huang, Yue Cui, Zehang Lin, Yusheng Liu, Shunzhi Zhu, Tatsat R. Patel, Adnan H. Siddiqui, Vincent M. Tutino, Maysam Orouskhani, Huayu Wang, Mahmud Mossa-Basha, Yuki Sato, Sven Hirsch, Susanne Wegener, Bjoern Menze
arXiv:2608.29246v1 Announce Type: cross
Abstract: Late gadolinium enhancement (LGE) cardiac magnetic resonance (MR) imaging is the modality of choice to assess myocardial infarction (MI) lesions. Now...
By Olivier Bernard, William A. Romero R., Cyprien Bouton, Celia Goujat, Hang Jung Ling, Pierre-Marc Jodoin, Fumin Guo, Calder Sheagren, Graham Wright, Abdul Qayyum, Moona Mazher, Steven A. Niederer, Hairui Wang, Xiaomei Wu, Franz Thaler, Gernot Plank, Martin Urschler, Ricardo M. Rosales, Esther Pueyo, Nicolas Duchateau, Frederic Cervenansky, Patrick Clarysse, Loic Belle, Thomas Bochaton, Nathan Mewton, Magalie Viallon, Pierre Croisille