Structure-property relationships are foundational to biology, chemistry and materials science, where function, reactivity and physical response emerge from spatial, chemical and periodic organization. Mechanistically explaining these relationships requires interpreting structural evidence through scientific principles and physical constraints, from stereochemistry and bonding to symmetry, energetics and periodic order.
The quadratic cost of causal self-attention severely bottlenecks long-context transformer inference. While numerous post hoc linearization pipelines exist, it is difficult to identify which components preserve model quality.
Analytical workloads operating on data stored in external database systems face a fundamental bottleneck: data access is guarded entirely by the database driver, like JDBC or ODBC, forcing all reads through query execution and other driver layers that are not designed for bulk columnar analytics. We present Jailbreak, an approach that bypasses the database engine entirely by reading storage files directly and materializing data as in-memory columnar buffers.
Autonomous AI agents can execute complex tasks with limited human review, yet they often lack the grounded operational knowledge to make their outputs not just executable but correct, secure, and maintainable. We introduce SkillCenter, to our knowledge the largest open skill library for agents by total count: 216,938 structured skills across 24 domain bundles.
Large language models hallucinate most about entities they have never seen. We ask whether a model's activations betray entity familiarity before a single answer token is generated, and whether that signal predicts the factual reliability of the answers.
EEG-based emotion recognition is critical for mental health monitoring and affective brain-computer interfaces, yet existing deep learning approaches often treat emotion classes as isolated labels, ignoring their psychological interdependencies. We propose a graph-regularized learning framework that conceptualizes emotions as nodes in a graph where edges encode proximity based on dimensional emotion theories.
Assigning Common Weakness Enumeration (CWE) categories to Common Vulnerabilities and Exposures (CVE) records remains an important but largely manual step in vulnerability analysis. We study this task as a text classification problem and compare two modelling choices: a \emph{multi-class} formulation that predicts a single CWE per CVE and a \emph{multi-label} formulation that allows multiple assignments.
Large language models (LLMs) have become significant providers of mental health support, yet they remain products of an attention economy whose operational and commercial targets favour sustained engagement over the friction that effective psychological support often requires. Developers' safety responses have been largely reactive, addressing the most visible and acute harms while subtler, longer-term patterns of risk (e.
AI agents that generate final answers based on user input often do not meet the needs of creative fields. Fields such as structural design and architecture need interactive systems that help users externalise and develop ideas, explore alternatives, and refine partial solutions.
Reinforcement learning (RL) is becoming increasingly important for post-training large language models (LLMs). Previous RL pipelines for LLMs were mostly synchronous and batch-interleaved, which is inefficient for long-horizon agentic tasks.
Spatial and Single-cell transcriptomics are transformative in deciphering cellular dynamics. As the fundamental paradigm for reconstructing cell developmental paths, trajectory inference (TI) is critical.
A self-evolving agent retires its bad skills by watching them fail, so what happens when the judge cannot see the failures? Skill retirement is the structural constraint that keeps a growing library from drifting below the no-skill baseline, but its guarantee assumes an unbiased reward, which is false for the LLM judges that reference-free tasks force upon us.
While whole-body multimodal medical imaging scanners have been increasingly recognized for more effective medical applications, the excessive long acquisition time in PET-MR scanning is a major obstacle in more efficient clinical practice. Deep learning-based MRI translation provides a potential solution to reduce scan duration.
Tool utilization enables Large Language Model (LLM) agents to interact with the real world and resolve complex tasks. However, existing agent frameworks predominantly rely on static toolsets composed of granular atomic actions (e.
Claims about the universality of human concepts have been predominantly assessed through linguistic similarity across languages and cultures. However, words are effective as communication devices because they compress rich experiential variation into shared conventions, potentially obscuring hidden individual and cultural differences in how concepts are mentally represented.
Video object segmentation (VOS) is a fundamental task in video understanding, requiring accurate delineation and consistent tracking of objects across frames. While supervised methods achieve strong performance, they rely on densely annotated datasets that are costly to obtain and have limited domain coverage.
Perceptual quality enhancement of severely compressed videos remains challenging due to complex artifact patterns and substantial information loss. Recent diffusion models have demonstrated strong generative capability for visual restoration, but directly applying them to compressed video often ignores compression degradation characteristics and may introduce structure-inconsistent hallucinations.
Pre-deployment safety evaluations aim to inform the downstream risks of releasing a new AI model. Yet most evaluations provide limited evidence about how often undesired model behavior will occur in deployment: they generally have insufficient coverage, are unrepresentative, and are generally recognizable as tests.
Document Visual Question Answering (DocVQA) presents a complex multimodal challenge, requiring models to exploit visual, textual, and layout information from documents. Although Vision-Language Models (VLMs) have shown remarkable performance in text-vision tasks, their robustness and transferability to different document domains remains underexplored.
Recent breakthroughs of Reinforcement Learning (RL) have highlighted its potential for complex agentic Large Language Model (LLM) tasks. However, existing efforts largely focus on single-task settings, whereas real-world deployment necessitates a generalist agent capable of solving multiple tasks simultaneously.