AI agents

Tool use, function calling, orchestration and the protocols that let models act rather than only answer.

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arXiv AI
Aug 13

VAKRA: Evaluating Multi-Hop Reasoning Across APIs and Retrieval Under Tool-Use Policies

arXiv:2608. 12282v1 Announce Type: new Abstract: Agents deployed in enterprise settings must reason across structured APIs and document collections, yet existing benchmarks evaluate these capabilities in isolation.

By Ankita Rajaram Naik, Anupama Murthi, Benjamin Elder, Siyu Huo, Raavi Gupta, Abhinav Jain, Praveen Venkateswaran, Abdulhamid Adebayo, Danish Contractor
arXiv Machine Learning
Aug 13

Unmasking Toxic Mimicry in Medical Offline Reinforcement Learning for ICU Sepsis Management via Counterfactual Clinical Audits

arXiv:2608. 11410v1 Announce Type: new Abstract: Offline reinforcement learning (RL) offers considerable promise for optimizing ICU treatment decisions, yet standard evaluation metrics Mean Squared Error (MSE) and Fitted Q-Evaluation (FQE) assess only behavioral imitation and cannot detect Toxic Mimicry, a failure mode in which agents replicate harmful patterns such as treatment withdrawal during comfort-care transitions.

By Hangqi Ren, Junyi Liao
arXiv AI
Aug 13

Retry, Switch, or Abstain? Learning Strategy-Aware Tool-Use Policies via Controlled Error Injection

arXiv:2608. 11977v1 Announce Type: new Abstract: Tool-using LLM agents are commonly trained and evaluated in environments where tool calls succeed reliably, yet deployed tools can fail transiently, persistently, or silently.

By Chaoran Chen, Vy Nguyen, Ziji Zhang, Abhinav Gullapalli, Ziyi Wang, Yuxuan Lu, Dakuo Wang, Jing Huang, Zhou Yu, Jin Lai
arXiv AI
Aug 13

A Modular Agentic Framework for Synthetically Constrained Multi-Objective Hit-to-Lead Optimization

arXiv:2608. 11483v1 Announce Type: new Abstract: Hit-to-lead optimization requires iterative design of hit analogs across competing potency, selectivity, physicochemical, pharmacokinetic, safety, and synthetic constraints.

By Kelvin P. Idanwekhai, Enes Kelestemur, Benjamin Strickland, Matthew Hart, Steini Davidsson, Angelos Angelopoulos, Ron Alterovitz, Marcello DeLuca, Alexander Tropsha
arXiv AI
Aug 13

Learning Loco-Manipulation From SMPC Demonstrations With Sparse Offline-to-Online RL

arXiv:2608. 12063v1 Announce Type: cross Abstract: Integrating locomotion and manipulation is essential for robot autonomy, but scaling standard Reinforcement Learning (RL) to complex tasks is severely bottlenecked by the slow, manual process of dense reward shaping.

By Martin Schuck, Maks Sorokin, Simone Manni, Duy Ta, Angela P. Schoellig, Marco Hutter, Simon Le Cleac'H, Jan Br\"udigam