The study audited ten different classifiers—including linear, tree‑ensemble, neural, glass‑box, and tabular foundation models—on national health survey data to predict myocardial infarction. By systematically removing features that could cause target leakage, the authors found that all models’ AUROC scores collapsed into a narrow band, indicating that reported high accuracy in prior work was largely due to leakage rather than model sophistication. The glass‑box explainable boosting machine performed comparably to other models while being much faster, and the authors demonstrated that fairness, calibration, and uncertainty can be audited and repaired without sacrificing performance.
By Raad Bin Tareaf, Murad Al-Rajab, Samia Loucif, Samer Ellaham, Cedric Schmitz
The paper introduces a missingness‑aware conformal calibration method for mortality prediction that accounts for cross‑hospital distribution shifts. By selecting a measurement on an independent sample, grouping patients by whether that measurement is recorded, and applying Mondrian calibration within each group, the method avoids reusing calibration outcomes. Experiments on eICU and MIMIC‑IV data show that, compared to pooled calibration, it reduces the worst‑group coverage gap by a median of 1.9 percentage points across six settings, though the benefit varies with predictor and hospital.
By Liang You, Dongwen Ou, Hengyu Shi, Siyuan Dai
arXiv:2606. 11267v1 Announce Type: new Abstract: Data leakage -- contamination of a model with information unavailable at baseline -- is the dominant reproducibility failure in machine-learning-based science, yet detection tools require training code, external data, or domain expertise.
By Laurence A. Jacobs
arXiv:2607. 28608v1 Announce Type: new Abstract: Clinical risk models routinely achieve strong aggregate performance while producing materially different error rates across patient subgroups.
By Sparsh Roy, Samuel Girmachew, Nishita Chavan
arXiv:2509. 19671v3 Announce Type: replace Abstract: Public datasets of Chest X-Rays (CXRs) have long been a popular benchmark for developing machine learning (ML) computer vision models in healthcare.
By Andrew Wang, Jiashuo Zhang, Michael Oberst
The paper introduces alert‑list concordance, a metric that evaluates whether different imputation strategies for ICU sepsis prediction models identify the same high‑risk patients, measured by Jaccard similarity of top‑k% alert sets with bootstrap confidence intervals. Using PhysioNet/CinC 2019 data, the authors compare nine imputation methods and a native‑missingness baseline, finding that many methods have similar AUROC yet produce alert lists that overlap only 51–75% of the time. ForwardFill stands out as an outlier, achieving higher discrimination but lower overlap (40–45%).
By Priyanka Siddappa, Muntaqim Ahmed Raju, Shifat Haider Al Amin, Ruizhe Ma