Hugging Face Trending Papers
Can You Trust Frozen Hematology Foundation Models under Acquisition Shift?
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arXiv Computer Vision
Aug 27
Can You Trust Frozen Hematology Foundation Models under Acquisition Shift?
The study evaluates 15 frozen hematology foundation-model embeddings across four single‑cell acquisition domains, finding that while in‑domain accuracy is near‑saturated (macro‑F1 0.98–0.997), cross‑dataset performance drops dramatically (34–72%) and model rankings shift. Probe‑dependent rank transfer is observed, with 1‑NN retrieval more stable than linear heads, yet neither reliably predicts target robustness. Calibration deteriorates off‑domain (ECE rises from 0.004 to 0.35), and exposure to internal cohorts confounds shift analysis; a training‑free pseudo‑label‑balanced feature normalization (CBR) modestly improves target‑prior robustness and calibration. whyItMatters":"The findings highlight that frozen hematology foundation models, though accurate in‑domain, may fail under realistic scanner, site, and class‑prior shifts, underscoring the need for comprehensive audits of accuracy, calibration, exposure, and robustness before clinical deployment."
arXiv AI
Aug 25
CRS-Bench: A Reference-Relative Reliability Benchmark for Medical Image Encoders
arXiv:2608.22059v1 Announce Type: cross Abstract: Pretrained image encoders are central to medical image classification, where expert annotation is costly and task-specific cohorts are often limited....
arXiv Computer Vision
Sep 30
HERO: Histology Encoder for Robust Representation in Oncology
HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.
arXiv Computer Vision
Sep 17
Lumen: Parameter-Efficient Alignment of Pretrained Vision and Language Encoders for Zero-Shot Computational Pathology
Lumen is a pathology vision‑language model that aligns frozen unimodal foundation models (Virchow2 and BioMedBERT) using rank‑4 adapters and projection heads, training only 0.40% of the total parameters on the QUILT‑1M corpus. It achieves the highest mean chance‑corrected balanced accuracy (0.546) across nine zero‑shot patch benchmarks and demonstrates strong performance on lymph‑node metastasis detection, with AUROC scores of 0.964 internally and 0.955 externally. While it ranks third in cross‑modal retrieval, Lumen’s low‑parameter training yields competitive results at both patch and slide levels.
arXiv Machine Learning
Aug 12
Retrieval-Augmented Vision Foundation Models for Robust Leukemia Cell Classification across Multiple Microscopy Datasets
arXiv:2608. 10657v1 Announce Type: cross Abstract: Leukemia cell image classification is challenged by real-world domain shifts from acquisition, staining, illumination, and site protocols, causing single-dataset models to generalize poorly in real clinical scenarios.
Hugging Face Trending Papers
Sep 30
Comparison of techniques for fine-tuning open-weight models for entity extraction from radiology reports
Converting free-text radiology reports into structured labels supports cohort building, quality assurance, and monitoring of clinical imaging models, but the strongest label extractors are hosted prop...