CRS-Bench: A Reference-Relative Reliability Benchmark for Medical Image Encoders
Read the original on arXiv AI →The Flow has not summarised this story yet — read it at arXiv AI.
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arXiv:2607. 26333v1 Announce Type: cross Abstract: Chest X-ray (CXR) machine learning relies heavily on automated evaluation using reference standards that aim to approximate clinical judgment.
MVC-Bench is a new benchmark designed to evaluate the calibration of vision‑language models (VLMs) and medical VLMs (Medical‑VLMs) for medical image classification. It tests calibration across robustness to modality, backbone, and domain shift; effectiveness of calibration strategies and prompt‑tuning methods; and stability under prompt‑template and random‑seed variations. The benchmark includes eight backbones, three medical modalities (fundus imaging, histopathology, chest X‑ray), and compares post‑hoc, train‑time, and zero‑shot calibration approaches, reporting accuracy, Expected Calibration Error (ECE), Maximum Calibration Error (MCE), and Adaptive Calibration Error (ACE) over 1,638 experiments, while also proposing a Multi‑Class Margin (MCM) regularization technique that improves ECE in most settings.
arXiv:2607. 20274v1 Announce Type: cross Abstract: Medical image encoders from different groups are increasingly treated as interchangeable, on the assumption that scale and clinical supervision concentrate their representations onto a shared structure.
The study evaluates 15 frozen hematology foundation-model embeddings across four single‑cell acquisition domains, finding that while in‑domain accuracy is near‑saturated (macro‑F1 0.98–0.997), cross‑dataset performance drops dramatically (34–72%) and model rankings shift. Probe‑dependent rank transfer is observed, with 1‑NN retrieval more stable than linear heads, yet neither reliably predicts target robustness. Calibration deteriorates off‑domain (ECE rises from 0.004 to 0.35), and exposure to internal cohorts confounds shift analysis; a training‑free pseudo‑label‑balanced feature normalization (CBR) modestly improves target‑prior robustness and calibration. whyItMatters":"The findings highlight that frozen hematology foundation models, though accurate in‑domain, may fail under realistic scanner, site, and class‑prior shifts, underscoring the need for comprehensive audits of accuracy, calibration, exposure, and robustness before clinical deployment."
The paper introduces a label‑free method called AURCC for selecting the best foundational model for medical image classification when the target domain lacks labels. AURCC uses a pseudo‑label discrepancy computed by the SUDO framework to score models without fine‑tuning. Experiments on chest X‑ray data across three inter‑hospital shifts show that AURCC closely matches the true model ranking, outperforming simple source‑accuracy baselines especially when source data are limited.
arXiv:2606. 15910v2 Announce Type: replace Abstract: A vision-language model can answer a question about a chest radiograph or a pathology slide fluently and confidently while barely using the image, relying instead on language priors.