arXiv AI
2d ago

Diagnostic-Guided Longitudinal Modeling for Forecasting Retinal Atrophy Progression

The study proposes a diagnostic-guided approach to choose between stochastic and deterministic longitudinal imaging models based on whether inter-visit changes are driven by disease progression or acquisition variability. Applied to a large, heterogeneous Optos fundus autofluorescence archive, the diagnostic revealed weak time-dependent changes and limited benefit from stochastic models, leading to the development of the deterministic Temporal Retinal U‑Net (TRU). TRU outperformed other classical and deep‑learning comparators on image‑level and eye‑specific progression metrics across held‑out and independent zero‑shot transfer cohorts, though with slightly lower precision in a smaller cross‑vendor cohort.

By Liyin Chen, Souvick Mukherjee, Ines Maria De Carvalho Lains, Nazlee Zebardast, Mengyu Wang, Tobias Elze, Jason I. Comander
Hugging Face Trending Papers
Aug 27

Domain-Specific Self-Supervised Representation Learning for Retinal Fundus Classification

The paper explores contrastive self‑supervised learning (SSL) for retinal fundus image classification, comparing SimSiam and SimCLR under limited data and computational resources. It investigates how retinal‑specific augmentation strategies and training parameters affect representation quality, evaluated through linear probing and fine‑tuning on multi‑disease classification and diabetic retinopathy grading tasks. The results demonstrate that tailored augmentations enable lightweight SSL models to learn transferable representations, reducing reliance on large annotated datasets while achieving competitive performance.

arXiv AI
Jul 23

Self-supervision drives representational convergence in medical foundation models more than clinical supervision

arXiv:2607. 20274v1 Announce Type: cross Abstract: Medical image encoders from different groups are increasingly treated as interchangeable, on the assumption that scale and clinical supervision concentrate their representations onto a shared structure.

By Soroosh Tayebi Arasteh, Sebastian Ziegelmayer, Mahshad Lotfinia, Lisa Adams, Sven Nebelung, Jakob Nikolas Kather, Daniel Truhn