arXiv:2608.23936v1 Announce Type: new
Abstract: We present a dynamical-systems based model for resting-state functional magnetic resonance imaging (rs-fMRI), trained on a dataset of roughly 40K rs-fM...
By Sourav Pal, Viet Luong, Hoseok Lee, Tingting Dan, Guorong Wu, Richard Davidson, Won Hwa Kim, Vikas Singh
arXiv:2604. 27277v3 Announce Type: replace-cross Abstract: Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data.
By Yizhou Wu, Shansong Wang, Yuheng Li, Mojtaba Safari, Mingzhe Hu, Chih-Wei Chang, Harini Veeraraghavan, Xiaofeng Yang
arXiv:2607. 26746v1 Announce Type: cross Abstract: Accurate identification of Alzheimers disease (AD) using resting-state functional magnetic resonance imaging (rs-fMRI) remains challenging due to the high dimensionality, noise, and complex inter-regional dependencies inherent in functional brain connectivity, which limit the effectiveness of traditional approaches based on handcrafted connectivity features or conventional machine learning models.
By Harshiddhi Pathak, Gowtham Reddy N, Mrinal Acharya, Manjunatha Mahadevappa
The paper introduces Latent Drift, a generative forecasting framework that predicts slow-evolving neurodegenerative disease progression by learning changes in a compressed semantic representation rather than full-resolution anatomy. It addresses two failure modes—identity collapse and continuous interpolation trap—by removing pixel-level identity from the prediction target and applying Finite Scalar Quantization to suppress high-frequency nuisance fluctuations. Experiments on longitudinal 3D brain MRI demonstrate that Latent Drift outperforms diffusion and autoregressive transformer baselines in both generative fidelity and clinically relevant metrics.
By Yuxiang Feng, Juncheng Wang, Chao Xu, Wenlong Hou, Huihan Wang, Yijie Qian, Yang Liu, Baigui Sun, Yong Liu, Shujun Wang
arXiv:2606. 15278v1 Announce Type: cross Abstract: Affective and cognitive disorders manifest as distributed, time-varying brain network dynamics across regions, channels, and time, challenging robust representation learning from EEG/sEEG for clinical diagnosis.
By Jinhan Liu, Mahsa Shoaran
arXiv:2602. 18195v2 Announce Type: replace-cross Abstract: Alzheimer's disease (AD) alters brain electrophysiology and disrupts multichannel EEG dynamics, making accurate and clinically useful EEG-based diagnosis increasingly important for screening and disease monitoring.
By Yicheng Feng, Hairong Chen, Ziyu Jia, Samir Bhatt, Hengguan Huang
arXiv:2603. 20452v2 Announce Type: replace Abstract: Longitudinal neuroimaging is essential for modeling disease progression in Alzheimer's disease (AD), yet irregular sampling and missing visits pose substantial challenges for learning reliable temporal representations.
By Ruiying Chen, Yutong Wang, Houliang Zhou, Wei Liang, Yong Chen, Lifang He
arXiv:2607. 17782v1 Announce Type: cross Abstract: Foundation models pretrained using self-supervised learning have transformed computer vision by learning transferable representations from large-scale unlabeled data.
By Moona Mazher, Abdul Qayyum, Steven A. Niederer, Daniel C. Alexander
The paper introduces a reverse spatio‑temporal disease progression model that reconstructs unobserved healthier anatomy from later diseased scans. It employs a two‑stage architecture: a frozen 3D vector‑quantised autoencoder creates a discrete latent space, and a Neural ODE learns continuous‑time dynamics, with a recurrent encoder initializing the latent state from reverse‑ordered observations. Experiments on a synthetic Morpho‑MNIST benchmark and longitudinal Alzheimer’s MRIs show the model can recover unseen prior states and outperform baseline methods in predicting healthy trajectories.
By Ulugbek Shernazarov, Moucheng Xu, Inomjon Ramatov
arXiv:2606. 10530v1 Announce Type: cross Abstract: Recent developments in brain recording are driving a demand for machine learning tools capable of decoding the latent structure of large populations of neurons.
By Shufeng Kong, Fumei Deng, Xinyi Dong, Caihua Liu, Weiwei Chen, Yingheng Wang, Daniel Cao, Azahara Oliva, Antonio Fernandez-Ruiz, Carla Gomes
EEGDM introduces a self‑supervised framework that uses latent diffusion models to generate EEG signals, moving beyond traditional masked reconstruction. The method employs an EEG encoder to produce a compact representation that conditions the diffusion denoising process, allowing joint optimization of encoder and generator. Experiments demonstrate that EEGDM can reconstruct high‑quality EEG, learn robust representations, and perform competitively on various downstream tasks.
By Shaocong Wang, Tong Liu, Yihan Li, Ming Li, Kairui Wen, Pei Yang, Wenqi Ji, Minjing Yu, Yong-Jin Liu
arXiv:2607. 06132v1 Announce Type: cross Abstract: Multi-Pool Chemical Exchange Saturation Transfer (CEST) MRI provides valuable metabolic information but is clinically limited by long acquisition times.
By Dexuan Li, Yupeng Wu, Chenglong Wang, Hanlin Liu, Hui Zhen, Jianqi Li, Guang Yang