arXiv:2607. 17782v1 Announce Type: cross Abstract: Foundation models pretrained using self-supervised learning have transformed computer vision by learning transferable representations from large-scale unlabeled data.
The paper introduces SYMBA, a self‑supervised pretraining framework tailored for structural T1‑weighted brain MRI. SYMBA uses anatomically constrained masking, a multi‑scale structural similarity reconstruction loss, and a progressive curriculum to capture distributed morphometric patterns. Evaluated on nine heterogeneous cohorts and two unseen datasets, SYMBA outperforms existing neuroimaging foundation models, achieving high AUROC scores for Alzheimer’s disease classification, mild cognitive impairment conversion, and amyloid status prediction, and shows strong sample efficiency in low‑label settings.
arXiv:2608.28787v1 Announce Type: new Abstract: Joint-embedding predictive architectures (JEPAs) have primarily been developed for self-supervised representation learning. Denoising JEPA (D-JEPA) rec...
The paper investigates combining a domain‑specific self‑supervised task—voxel‑level brain age prediction—with a general task—image inpainting—to pretrain models for brain MRI segmentation. A multitask pretraining framework jointly optimizes both objectives, yielding representations that outperform single‑task pretraining and training from scratch on three segmentation benchmarks (multiple sclerosis lesions, ischemic stroke lesions, and cortical structures). The study demonstrates that integrating domain‑specific and general self‑supervised tasks benefits the development of generalizable neuroimaging foundation models.
arXiv:2604. 27277v3 Announce Type: replace-cross Abstract: Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data.
Rhamba is a region‑aware pretraining framework for resting‑state fMRI that combines anatomically guided masking with hybrid Attention‑Mamba architectures. The study pretrained models on the ABIDE dataset using three masking strategies (Any, Majority, Pure) and evaluated four architectural variants, finding that the Mamba‑Attention (MA) hybrid achieved the best average AUROC on downstream schizophrenia and ADHD classification tasks. Explainable AI via Integrated Gradients highlighted that performance depends on the interaction between masking strategy and architecture rather than a single dominant configuration.
arXiv:2607. 11962v1 Announce Type: cross Abstract: Self-supervised learning offers a compelling approach for medical imaging, where labeled data are scarce and acquisition costs are high.
The study investigates whether self‑supervised learning can produce useful representations from fMRI data alone. Using a joint embedding predictive architecture, participant‑specific encoders are trained without access to stimulus images or derived representations. The resulting embeddings perform competitively on brain captioning, image reconstruction, and cross‑participant generalization, and can be aligned unsupervised across participants, enabling a decoding head trained on one subject to work on another with minimal loss of performance.
arXiv:2606. 19651v1 Announce Type: new Abstract: Three-dimensional (3D) brain MRI is central to clinical neurology and neuro-oncology, where generative models could augment under-represented cohorts, simulate disease trajectories, and support privacy-preserving data sharing.
arXiv:2605. 23995v4 Announce Type: replace-cross Abstract: Self-supervised learning (SSL) is increasingly used in medical image analysis to reduce dependence on costly expert annotations by learning transferable representations from unlabeled data.
arXiv:2610.28411v1 Announce Type: cross Abstract: Deep learning models have become essential tools in medical imaging, yet training them end-to-end for diverse tasks remains challenging due to limite...
arXiv:2605.05522v3 Announce Type: replace-cross Abstract: Although self-supervised pretraining is expected to learn broadly transferable representations, its effectiveness across imaging modalities s...