arXiv Machine Learning

Literature-Guided Minimax Optimization of Virtual Epilepsy Neurostimulation

arXiv:2606. 04339v1 Announce Type: new Abstract: Computational models of epilepsy promise patient-specific treatment design, but most optimization workflows still search for parameters that perform well on average.

arXiv Machine Learning
Aug 28

Robust Neural Stimulation Response Modeling Through Meta-Learning and Pretraining

The study introduces a meta-learning and pretraining approach to improve neural stimulation response modeling. By extending temporal basis function models with a MAML-based architecture, the authors demonstrate a significant reduction in catastrophic forecast failures and narrower prediction intervals across 40 optogenetic stimulation sessions in non-human primates. The method also cuts calibration requirements by 50–90%, making closed‑loop stimulation more feasible within clinical time constraints.

By Matthew J Bryan, Daniel C Muir, Felix Schwock, Azadeh Yazdan-Shahmorad, Rajesh P N Rao
arXiv AI
4d ago

PHASE: A Physiology-Guided Hierarchical Foundation Model for Intracranial EEG

arXiv:2609.36087v1 Announce Type: cross Abstract: Clinicians and neuroscientists have long analyzed intracranial electroencephalography (iEEG) through directly measurable physiological characteristic...

By Yipeng Zhang, Chenda Duan, Yuanyi Ding, Tianyi Wang, Atsuro Daida, Masaki Izumi, Yuta Tanoue, Naoto Kuroda, Shaun A. Hussain, Nishant Sinha, Eishi Asano. Hiroki Nariai, Vwani Roychowdhury
arXiv AI
Jun 2

CLSP-REQA: A Real-Time Quality-Aware Closed-Loop Seizure Prediction Framework with Mamba-BiLSTM and Confidence-Gated Intervention

arXiv:2606. 00074v1 Announce Type: cross Abstract: Reliable seizure prediction is a prerequisite for closed-loop neurostimulation therapy, yet existing methods rarely account for the variability in EEG signal quality encountered in real-world deployment, and the overwhelming majority adopt non-strict evaluation protocols that overestimate generalisation performance.

By Mufeng Chen, Qi Wu, Bingchao Huang, Xiwen Lai, Zekai Chen, Xinge Ouyang, Quansheng Ren
arXiv AI
Sep 24

AI-Driven Neural Surrogates for In Silico Design of Cognitive-Affective Neuromodulation Targets

arXiv:2609.27729v1 Announce Type: cross Abstract: In neuropsychiatry, the primary goal is often not only to decode brain activity but to change it, for example to lessen a negative affective bias or...

By Marco Rothermel, Madleen Stenger, Soroush Daftarian, Svenja Jule Francke, Bita Shariatpanahi, Jos\'e C. Garc\'ia Alanis, Mohammad-Ali Nikouei Mahani, Stefan G. Hofmann, Tim Hahn, Hamidreza Jamalabadi
Hugging Face Trending Papers
Aug 27

Robust Neural Stimulation Response Modeling Through Meta-Learning and Pretraining

The paper demonstrates that meta‑learning and pretraining can improve neural stimulation response models, reducing catastrophic forecast failures and narrowing prediction intervals. Using temporal basis function models with a MAML‑based architecture, the authors evaluated 40 optogenetic stimulation sessions in non‑human primates and found that a 1,000‑sample calibration set reduced poor‑performance sessions from 16 to 1. Calibration needs were cut by 50–90%, making closed‑loop stimulation feasible within clinical time limits.

arXiv AI
Jul 14

DiffEEG: A Self-Supervised Denoising Diffusion Model for Learning EEG Generic Representations

arXiv:2607. 11578v1 Announce Type: cross Abstract: Deep learning for EEG-based seizure detection faces critical challenges: severe annotation scarcity and extreme class imbalance, where ictal events comprise less than 10\% of clinical recordings.

By Abdulkader Helwan, Lina Abou-Abbas, Hussein El Amouri, Belkacem Chikhaoui, Khadidja Henni
arXiv Computer Vision
Aug 28

Virtual iEEG from Scalp EEG: Charting the Landscape of Source Imaging, Intracranial Inference and Reconstruction

The article reviews the emerging field of virtual intracranial EEG (iEEG) derived from scalp EEG recordings. It introduces a target‑centred framework that separates event inference, feature translation, and waveform reconstruction, and it evaluates evidence based on cohort independence, coverage, and validation rigor. Current research shows limited success in inferring specific intracranial events and low‑frequency activity, but it has not yet achieved reliable reconstruction of arbitrary contact‑level signals.

By Dongyi He, Xiangkai Wang, Hongjie Yan, Luping Song, Wai Ting Siok, Nizhuan Wang