arXiv AI By Marco Rothermel, Madleen Stenger, Soroush Daftarian, Svenja Jule Francke, Bita Shariatpanahi, Jos\'e C. Garc\'ia Alanis, Mohammad-Ali Nikouei Mahani, Stefan G. Hofmann, Tim Hahn, Hamidreza Jamalabadi

AI-Driven Neural Surrogates for In Silico Design of Cognitive-Affective Neuromodulation Targets

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arXiv AI
Sep 21

Rhamba: Region-Aware Hybrid Attention-Mamba Framework for Self-Supervised Learning in Resting-State fMRI

Rhamba is a region‑aware pretraining framework for resting‑state fMRI that combines anatomically guided masking with hybrid Attention‑Mamba architectures. The study pretrained models on the ABIDE dataset using three masking strategies (Any, Majority, Pure) and evaluated four architectural variants, finding that the Mamba‑Attention (MA) hybrid achieved the best average AUROC on downstream schizophrenia and ADHD classification tasks. Explainable AI via Integrated Gradients highlighted that performance depends on the interaction between masking strategy and architecture rather than a single dominant configuration.

By Pankaj Pandey, Ruthwik Reddy Doodipala, Pratheek Eranki, Carolina Torres-Rojas, Manob Jyoti Saikia, Ranganatha Sitaram