The CXR‑LT 2026 Challenge introduces a multi‑center, long‑tailed chest X‑ray classification benchmark with over 145,000 radiologist‑annotated images from PadChest and NIH datasets. It defines two core tasks: robust multi‑label classification on 30 known classes and open‑world generalization to 6 unseen rare disease classes. The paper outlines data collection, annotation, solution strategies, and evaluates performance across head‑vs‑tail, calibration, and cross‑center gaps, noting that vision‑language models improve in‑distribution and zero‑shot performance but rare‑finding detection under multi‑center shift remains difficult.
By Hexin Dong, Yi Lin, Pengyu Zhou, Fengnian Zhao, Alan Clint Legasto, Juno Cho, Dohui Kim, Justin Namuk Kim, Mingeon Kim, Sunwoo Kwak, Gabriel Moy\`a-Alcover, Ky Trung Nguyen, Thanh-Huy Nguyen, Ha-Hieu Pham, Huy-Hieu Pham, Huy Le Pham, Nikhileswara Rao Sulake, Aina Tur-Serrano, Ruichi Zhang, Ang Zu, Adam E. Flanders, Zhiyong Lu, Ronald M. Summers, Mingquan Lin, Hao Chen, Yuzhe Yang, George Shih, Yifan Peng
arXiv:2608. 00442v2 Announce Type: replace-cross Abstract: Medical anomaly detection identifies abnormal images and localizes lesions under scarce supervision while generalizing across organs and modalities.
By Yibo Wan, Jinyu Cai, See-kiong Ng
AlphaRAD introduces a grounded zero‑shot classification framework for chest radiology that leverages structured medical concepts extracted from reports and a novel α‑Corrected Binary Cross‑Entropy loss to reduce in‑batch noise. It also presents FLaS, a lightweight cross‑modal fusion module that factorizes VLPM representations into independent subspaces, improving spatial grounding without adding parameters. The method achieves state‑of‑the‑art performance on 16 classification benchmarks and sets new records on several grounding, phrase‑grounding, and segmentation datasets.
By Jianzhong You, Yuan Gao, Chris McIntosh
Vision-language pre-training (VLP) holds great promise for general-purpose medical AI by leveraging radiology reports as rich textual supervision, yet existing methods struggle with 3D CT imaging due to inefficient visual backbones and coarse semantic alignment. To address these issues, we propose a tailored VLP framework featuring three key components: (1) a CNN-ViT hybrid encoder that replaces ViT's patch embedding with a 3D CNN backbone to efficiently capture local anatomical details while preserving global attention and compatibility with pre-trained cross-modal priors; (2) a disease-level contrastive learning mechanism using learnable query tokens to dynamically extract disease-specific semantics from full reports and align them with corresponding visual features, thereby disentangling distinct diseases within the same anatomical region; and (3) a diagnosis-aware prompt strategy that employs real clinical phrases and aggregated disease prototypes to bridge the pre-training-inference gap and enhance zero-shot diagnostic reliability.
arXiv:2510. 15042v3 Announce Type: replace-cross Abstract: In the 3D medical image domain, vision-language pre-training is used to create vision-language encoders (VLEs) that can support radiologists by retrieving patients with similar abnormalities, predicting likelihoods of abnormality, or, with downstream adaptation, generating radiological reports.
By Tassilo Wald, Ibrahim Ethem Hamamci, Yuan Gao, Sam Bond-Taylor, Harshita Sharma, Maximilian Ilse, Cynthia Lo, Olesya Melnichenko, Anton Schwaighofer, Noel C. F. Codella, Maria Teodora Wetscherek, Klaus H. Maier-Hein, Panagiotis Korfiatis, Valentina Salvatelli, Javier Alvarez-Valle, Fernando P\'erez-Garc\'ia
arXiv:2609.39266v1 Announce Type: new
Abstract: Fine-grained vision-language alignment in chest radiography enables zero-shot classification, grounding, and segmentation without task-specific annotat...
By Qixing Zhao, Jinpeng Li
AdaptiveCDM is a modular framework for source‑free few‑shot domain adaptation in cell detection, enabling a pretrained model to adapt to new imaging domains using only a handful of labeled target images and no source data. It combines Resolution‑Aware Augmentation (RAug) to balance scarce, class‑imbalanced samples while preserving cellular morphology, and Category‑Aware Representation Learning (CARL) to strengthen class‑consistent proposals for better localization and classification. Experiments on M5 and Raabin‑WBC datasets show that AdaptiveCDM achieves competitive or superior mAP scores compared to state‑of‑the‑art methods under their respective supervision settings.
By Nimra Dilawar, Sara Nadeem, Javed Iqbal, Waqas Sultani, Mohsen Ali
arXiv:2506.10633v2 Announce Type: replace
Abstract: Latent Diffusion Models have shown remarkable results in text-guided image synthesis in recent years. In the domain of natural (RGB) images, recent...
By Konstantinos Vilouras, Ilias Stogiannidis, Junyu Yan, Alison Q. O'Neil, Sotirios A. Tsaftaris
arXiv:2608.28455v1 Announce Type: new
Abstract: Contrastive vision-language learning uses paired chest CT volumes and radiology reports to learn abnormality classifiers without manually annotated lab...
By Huseyin Umut Isik, Mehmet Alp Ozaydin, Sila Kurugol, \c{S}eyda Ertekin
arXiv:2606. 03180v1 Announce Type: cross Abstract: Vision-language models (VLMs) for radiology have emerged as a scalable paradigm by leveraging image-report pairs naturally produced in clinical workflows.
By Jonggwon Park, Seongeun Lee, Junhyun Park, Hannah Yun, Hyunwoong Kim, Sohyun Jeong, Hyewon Kang, Byungmu Yoon, Kyoyun Choi
Instance-Guided Report Anchoring (IGRA) is a model-agnostic module that links each abnormality instance in a chest CT to the corresponding finding in a radiology report during training, while discarding text components at inference. By reformulating free-text grounding as multi-label volumetric segmentation, IGRA allows all abnormality categories to be predicted in a single image-only forward pass. The method improves Dice scores by 22.5% over the strongest image-only baseline and matches state‑of‑the‑art performance on single-finding subsets, with consistent gains across multiple 3D segmentation backbones and datasets.
By Zhenyu Bu, Haoyan Ding, Chushu Shen, Xinyuan Zheng, Peiyu Duan, Xueqi Guo, Sepehr Farhand, Yoshihisa Shinagawa, Gerardo Hermosillo, Chaowei Wu
arXiv:2607. 09562v1 Announce Type: cross Abstract: Medical Vision-Language Models (VLMs) exhibit strong zero-shot performance, yet their effectiveness still declines on out-of-distribution (OOD) data due to domain shifts and class bias inherited from large-scale pretraining.
By Tianyou Jiang, Ziyu Zhou