arXiv:2606. 11570v1 Announce Type: cross Abstract: We propose a spectral-based, unsupervised representation learning framework to derive low-dimensional embeddings for clinical concepts and patients in rare disease cohorts from electronic health records, where data are high-dimensional but sample sizes are limited.
arXiv:2608. 06430v1 Announce Type: new Abstract: Learning from Electronic Health Records (EHRs) has gained significant attention due to its potential to improve clinical prediction.
arXiv:2608. 14657v1 Announce Type: new Abstract: Early identification of lung cancer risk is critical for timely intervention, yet existing prediction models are limited by their reliance on single data modalities and their inability to leverage structured clinical knowledge.
arXiv:2604. 01841v2 Announce Type: replace Abstract: Clinical prediction from structured electronic health records (EHRs) is challenging due to high dimensionality, heterogeneity, class imbalance, and distribution shift.
The paper introduces the Relational Hypergraph Transformer (RHT), a unified architecture that models relational databases as hypergraphs and learns pentadimensional embeddings (PentE). RHT applies sparse relational attention whose complexity scales with the average relational degree, making it computationally efficient for large, high‑dimensional, and high‑cardinality datasets. Experiments on the Synthea synthetic electronic health record dataset show that RHT produces more semantically coherent embeddings than tabular, relational, and temporal graph baselines, while remaining scalable, and the authors provide an open‑source implementation and plan clinical validation on MIMIC‑IV.
arXiv:2601. 18128v2 Announce Type: replace-cross Abstract: High-dimensional data often exhibit variation that can be captured by lower-dimensional factors.
arXiv:2606. 12362v1 Announce Type: cross Abstract: We study multimodal learning under missing modalities, with particular motivation from bioscience applications in which heterogeneous modalities are often only partially available when decisions need to be made.
arXiv:2608. 16507v1 Announce Type: new Abstract: Due to the limited amount of information, modeling longitudinal rare-disease data can benefit from integrating clinical knowledge.
The paper investigates Partial Least Squares (PLS) in high-dimensional settings, focusing on a model where two data matrices share a low-rank latent structure plus individual-specific components. By analyzing the singular vectors of the cross‑covariance matrix with random matrix theory, the authors derive asymptotic characterizations of how well the estimated latent directions align with the true ones. They show that the PLS variant based on Singular Value Decomposition (PLS‑SVD) outperforms separate principal component analysis in detecting the common latent subspace, while also identifying regimes where PLS‑SVD behaves counter‑intuitively or reaches fundamental limits.
arXiv:2602. 12542v2 Announce Type: replace-cross Abstract: Deep learning models for clinical event prediction on electronic health records (EHR) often suffer performance degradation when deployed under different data distributions.
arXiv:2403. 14926v3 Announce Type: replace-cross Abstract: Electronic health record (EHR) systems capture a wealth of multimodal clinical data, encompassing both structured clinical codes and unstructured clinical notes.
arXiv:2407. 01718v2 Announce Type: replace-cross Abstract: Embedding high-dimensional data into a low-dimensional space is an indispensable component of data analysis.
arXiv:2608. 00935v1 Announce Type: new Abstract: Electronic Health Records (EHRs) are widely used for clinical risk prediction using machine learning.