arXiv:2606. 28798v1 Announce Type: new Abstract: Objective: ICD codes are central to reimbursement, research, and population health surveillance, yet automated coding systems often struggle to integrate diagnostic signals from both clinical narratives and structured electronic health record (EHR) variables.
By Chengyuan Liu, Xinyue Zhang, Yao Li, Guanting Chen
arXiv:2605.20292v2 Announce Type: replace
Abstract: Numerical time-series models effectively process irregular electronic health record (EHR) trajectories, but do not expose which temporal patterns s...
By Kwanhyung Lee, Juhwan Choi, Jongheon Kim, Joohyung Lee, Hyeongwon Jang, Jeonguk Lee, Jisoo Jung, Eunho Yang
arXiv:2607. 15447v1 Announce Type: new Abstract: Recent research in clinical machine learning, focusing on outcome predictions in intensive care unit (ICU), has shifted from bespoke supervised models to foundation models, utilising modern representation learning methods.
By Jingteng Li, Alexander Capstick, Louise Rigny, Iona Biggart, Neil J Sebire, Payam Barnaghi
arXiv:2607. 15380v1 Announce Type: cross Abstract: Electronic health records combine free-text clinical narratives with structured measurements such as vital signs, laboratory values, and comorbidities.
By Ajay Madhavan Ravichandran, Bilgin Osmandoja, Klemens Budde, Klaus Netter, Tobias Strapatsas, Aljoscha Burchardt, Sebastian M\"oller, Roland Roller
arXiv:2606.28798v2 Announce Type: replace
Abstract: The main objective of this paper is to propose a general framework for prediction based on different sources of multimodal data in the healthcare d...
By Chengyuan Liu, Xinyue Zhang, Yao Li, Guanting Chen
arXiv:2608.29582v1 Announce Type: cross
Abstract: Current evaluations of large language models (LLMs) primarily focus on factual knowledge retrieval, overlooking the fundamental challenge of navigati...
By Yi Yu, Bo Wang, Chong Feng, Ge Shi, Xia Liu, Ziyi Yang, Xuewen Shi
arXiv:2509.19375v2 Announce Type: replace-cross
Abstract: Large language models are increasingly used for clinical text classification, where overconfident misclassifications can directly affect pati...
By Mridul Sharma, Adeetya Patel, Zaneta D' Souza, Samira Abbasgholizadeh Rahimi, Siva Reddy, Sreenath Madathil
The paper introduces a unified pre‑training framework for medical representations that incorporates hierarchical sub‑token aggregation, partial masking, and cross‑reference mechanisms to better capture the structure of medical codes. The resulting model outperforms existing BERT‑based approaches on pre‑training tasks and downstream clinical predictions, such as dementia onset and hospitalization. An in‑silico drug repositioning study for Alzheimer’s disease demonstrates the framework’s ability to rediscover known drugs and prioritize new hypotheses without external literature, establishing a workflow for hypothesis generation and prioritization based on observational data.
By Yuhei Fujioka, Daitaro Misawa, Shingo Fukuma
arXiv:2608.28624v1 Announce Type: cross
Abstract: Accurate interpretation of single-visit and longitudinal clinical assessments for Parkinson's disease is time-consuming and often depends on speciali...
By Sana Alamgeera, Denise Goberta, Muhammad Irshad, Anne H. H. Ngu
arXiv:2606. 08945v1 Announce Type: new Abstract: We investigate whether information about time-to-event risk estimated by a Cox proportional hazards model can be transferred into a generative large language model.
By Nicholas I-Hsien Kuo, Blanca Gallego, Louisa Jorm
We investigate whether information about time-to-event risk estimated by a Cox proportional hazards model can be transferred into a generative large language model. We propose a text-based survival modelling pipeline in which structured clinical covariates are converted into text prompts and a Qwen-based large language model is fine-tuned to generate patient-specific survival risk using Cox model predictions as a training target.
arXiv:2604. 06684v2 Announce Type: replace Abstract: Clinical reasoning over electronic health records (EHRs) is a fundamental yet challenging task in modern healthcare.
By Yue Fang, Weibin Liao, Yuxin Guo, Jiaran Gao, Hongxin Ding, Jinyang Zhang, Xinke Jiang, Zhibang Yang, Junfeng Zhao, Yasha Wang, Liantao Ma