arXiv Machine Learning

Nonlinear multi-study sparse factor analysis

arXiv:2601. 18128v2 Announce Type: replace-cross Abstract: High-dimensional data often exhibit variation that can be captured by lower-dimensional factors.

arXiv Machine Learning
Jun 11

Enhancing Spectral Embedding through Robust and Flexible Knowledge Transfer in Electronic Health Records

arXiv:2606. 11570v1 Announce Type: cross Abstract: We propose a spectral-based, unsupervised representation learning framework to derive low-dimensional embeddings for clinical concepts and patients in rare disease cohorts from electronic health records, where data are high-dimensional but sample sizes are limited.

By Feiqing Huang, Zongqi Xia, Rong Ma, Tianxi Cai
arXiv Machine Learning
Aug 31

EXPOSE: Explainable and Domain-Robust Embeddings from Pathology Vision Foundation Models using Sparse Autoencoders

EXPOSE is a framework that applies Sparse Autoencoders to Vision Foundation Model embeddings in computational pathology, aiming to separate biological signals from domain‑specific noise. By training a sparse representation of VFM features and using a linear classifier to flag domain‑specific latent dimensions, the method masks these components before downstream relapse prediction, avoiding the need to retrain the backbone model. Experiments on a large prostate cancer dataset demonstrate that removing domain‑specific features improves cross‑domain performance and raises the Domain Robustness Index (DoRI).

By Anja Witte, Maximilian Lennartz, Jan Baumbach, Guido Sauter, Stefan Bonn, Patrick Fuhlert, Marina Zimmermann
arXiv Machine Learning
Aug 3

Nonparametric Partial Disentanglement via Mechanism Sparsity: Sparse Actions, Interventions and Sparse Temporal Dependencies

arXiv:2401. 04890v2 Announce Type: replace-cross Abstract: This work introduces a novel principle for disentanglement we call mechanism sparsity regularization, which applies when the latent factors of interest depend sparsely on observed auxiliary variables and/or past latent factors.

By S\'ebastien Lachapelle, Pau Rodr\'iguez L\'opez, Yash Sharma, Katie Everett, R\'emi Le Priol, Alexandre Lacoste, Simon Lacoste-Julien
arXiv Statistics ML
Aug 25

Neuro-Causal Factor Analysis

Neuro-Causal Factor Analysis (NCFA) reimagines traditional factor analysis by integrating causal structure learning and deep generative modeling. The method learns a directed graph linking latent and observed variables, then trains a deep generative model that respects the graph’s Markov factorization. Experiments on synthetic and real datasets show NCFA achieves lower reconstruction error than standard FA and better latent distribution recovery than a variational autoencoder, while offering a sparser architecture, reduced complexity, and causal interpretability.

By Alex Markham, Mingyu Liu, Bryon Aragam, Liam Solus