arXiv Machine Learning

MiGHT-EHR: A Multi-task Graph Transformer for Heterogeneous Temporal Electronic Health Records

arXiv:2608. 06430v1 Announce Type: new Abstract: Learning from Electronic Health Records (EHRs) has gained significant attention due to its potential to improve clinical prediction.

arXiv Machine Learning
Aug 4

EHR2Path: Comprehensive Pathway-Level Modeling of Longitudinal Patient Trajectories from Multimodal Electronic Health Records

arXiv:2506. 04831v3 Announce Type: replace Abstract: Forecasting how a patient's condition is likely to evolve, including possible deterioration, recovery, treatment needs, and care transitions, could support more proactive and personalized care, but requires modeling heterogeneous and longitudinal electronic health record (EHR) data.

By Chantal Pellegrini, Ege \"Ozsoy, David Bani-Harouni, Matthias Keicher, Nassir Navab
arXiv Machine Learning
Jul 20

LLM4EHR: Aligning Clinical Time Series with Medical Event Sequences via Large Language Models

arXiv:2607. 15447v1 Announce Type: new Abstract: Recent research in clinical machine learning, focusing on outcome predictions in intensive care unit (ICU), has shifted from bespoke supervised models to foundation models, utilising modern representation learning methods.

By Jingteng Li, Alexander Capstick, Louise Rigny, Iona Biggart, Neil J Sebire, Payam Barnaghi
arXiv AI
Sep 7

REFINE: LLM Refinement over Budgeted Text-Attributed Graphs for Personalized Medical Concept Representation

REFINE is a framework that refines medical concept representations by creating patient‑specific temporal graphs from a global text‑attributed knowledge graph. It uses a reinforcement learning policy to allocate a personalized graph expansion budget for each observed code, then processes the resulting graph with a heterogeneous GNN and a frozen LLM that refines representations via graph‑aware soft prompts. Experiments on MIMIC‑III and MIMIC‑IV demonstrate that REFINE consistently improves various EHR prediction backbones, surpasses strong baselines, and shows robust gains across ablation studies, KG selection, and data insufficiency scenarios.

By Mohsen Nayebi Kerdabadi, Arya Hadizadeh Moghaddam, Dongjie Wang, Zijun Yao
arXiv AI
Jul 22

Trajectory-Aware Clinical Risk Prediction via Severity-Grounded Knowledge Graphs and Retrieval-Augmented Generation

arXiv:2607. 18270v1 Announce Type: new Abstract: While Electronic Health Records (EHRs) offer a wealth of clinical data, effectively augmenting a patient's records with heterogeneous external knowledge to predict the patient's clinical risk remains a significant challenge.

By Kyunghoon Jeon, Youmin Ko, Woohwan Jung, Hyunjoon Kim
Hugging Face Trending Papers
Sep 8

NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

NOAH is a generative transformer that models the entire multimodal patient journey by integrating bidirectional time and a variational latent space to capture continuous, stochastic clinical trajectories. Trained on over 559 million events from 431,000 hospital visits, it processes medical images, time‑series, numeric signals, categorical events, and both structured and unstructured records. The model supports autoregressive forecasting, zero‑shot classification, and counterfactual simulations, yielding strong predictive performance across 15 ICD chapters, 29 comorbidities, and time‑to‑event outcomes.

arXiv AI
Sep 10

NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

NOAH is a generative transformer that learns the full multimodal patient journey by integrating bidirectional time and a variational latent space. Trained on over 559 million clinical events from 431,000 hospital visits, it processes medical images, time‑series, numeric signals, categorical events, and both structured and unstructured records. The model supports autoregressive forecasting, zero‑shot classification, and counterfactual intervention simulation, yielding strong performance on clinical outcomes, ICD chapters, comorbidities, and time‑to‑event prediction.

By Tobias Susetzky, Raphael Rehms, Dmitrii Seletkov, \"Ozg\"un Turgut, Michelle Espranita Liman, Lisa Steinhelfer, Rickmer Braren, Daniel Rueckert
arXiv AI
Jun 3

ChatHealthAI: Aligning Electronic Health Record Representations with Large Language Models for Grounded Clinical Reasoning

arXiv:2606. 02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs).

By Bo-Hong Wang, Baicheng Peng, Ruilin Wang, Jun Bai, Ziyang Song, Yue Li