arXiv AI

Methodological and Conceptual Framework for 5D Multi-Table Analysis: A Unified Approach for Complex Data Reuse

The paper introduces the Relational Hypergraph Transformer (RHT), a unified architecture that models relational databases as hypergraphs and learns pentadimensional embeddings (PentE). RHT applies sparse relational attention whose complexity scales with the average relational degree, making it computationally efficient for large, high‑dimensional, and high‑cardinality datasets. Experiments on the Synthea synthetic electronic health record dataset show that RHT produces more semantically coherent embeddings than tabular, relational, and temporal graph baselines, while remaining scalable, and the authors provide an open‑source implementation and plan clinical validation on MIMIC‑IV.

arXiv AI
Jun 2

Retrieval-aligned Tabular Foundation Models Enable Robust Clinical Risk Prediction in Electronic Health Records Under Real-world Constraints

arXiv:2604. 01841v2 Announce Type: replace Abstract: Clinical prediction from structured electronic health records (EHRs) is challenging due to high dimensionality, heterogeneity, class imbalance, and distribution shift.

By Minh-Khoi Pham, Thang-Long Nguyen Ho, Thao Thi Phuong Dao, Tai Tan Mai, Minh-Triet Tran, Marie E. Ward, Una Geary, Rob Brennan, Nick McDonald, Martin Crane, Marija Bezbradica
arXiv AI
Jun 16

Hierarchical Modeling of ICD Codes in EHR Foundation Models

arXiv:2606. 15447v1 Announce Type: new Abstract: Electronic health record foundation models typically treat ICD diagnosis codes as flat tokens, overlooking the clinically meaningful hierarchical structure that captures disease families, subcategories, and fine-grained diagnostic detail.

By Megha Thukral, Dong Gyun Kang, Rudra Pratap Singh, Shruthi Kashinath Hiremath, Katrin H\"ansel, Thomas Pl\"otz
arXiv AI
Sep 7

REFINE: LLM Refinement over Budgeted Text-Attributed Graphs for Personalized Medical Concept Representation

REFINE is a framework that refines medical concept representations by creating patient‑specific temporal graphs from a global text‑attributed knowledge graph. It uses a reinforcement learning policy to allocate a personalized graph expansion budget for each observed code, then processes the resulting graph with a heterogeneous GNN and a frozen LLM that refines representations via graph‑aware soft prompts. Experiments on MIMIC‑III and MIMIC‑IV demonstrate that REFINE consistently improves various EHR prediction backbones, surpasses strong baselines, and shows robust gains across ablation studies, KG selection, and data insufficiency scenarios.

By Mohsen Nayebi Kerdabadi, Arya Hadizadeh Moghaddam, Dongjie Wang, Zijun Yao
arXiv AI
Jun 8

REMEDI: A Benchmark for Retention and Unlearning Evaluation in Multi-label Clinical Disease Inference

arXiv:2606. 07141v1 Announce Type: cross Abstract: Language models trained for clinical disease inference are trained on patient data, which may include sensitive and private information, and data owners may request the removal of their data from a trained model due to privacy or copyright concerns.

By Anurag Sharma, Sai Teja Chunchu, Prasenjit Mitra, Sandipan Sikdar, Koustav Rudra