arXiv AI

SCOPE-AD: Sequential cost-aware ordinal-belief planning with energy-based models for diagnostic agents

arXiv:2610. 01278v1 Announce Type: new Abstract: Alzheimer's disease (AD) diagnosis requires sequential evidence acquisition under heterogeneous test costs and patient burden.

arXiv Machine Learning
4d ago

NeuronSifter: Intervention Planning in CNS Microenvironments

NeuronSifter is a framework for planning interventions in central nervous system microenvironments by converting treatment regimens into state‑conditional target‑occupancy fields and propagating them through microenvironment dynamics. It selects measurements based on their expected reduction in intervention loss, integrating typed outcomes into a unified posterior. In synthetic Alzheimer’s disease scenarios, occupancy conditioning improves trajectory probability scores and intervention ordering accuracy, and decision‑directed acquisition reduces terminal risk compared to a Bayesian experimental design planner.

By Haowei Xu, Wanyi Fu, Hongbin Han, Zhaoheng Xie
arXiv Machine Learning
Jul 14

Imputation-free transformer learning enables robust Alzheimer's disease prediction and calibrated uncertainty quantification across heterogeneous clinical cohorts

arXiv:2607. 11656v1 Announce Type: cross Abstract: Accurate diagnostic classification and disease-severity prediction for Alzheimer's disease are hampered by the incompleteness and heterogeneity of real-world clinical data.

By Christelle Schneuwly Diaz, Narmina Baghirova, Duy-Thanh Vu, Duy-Cat Can, Gilles Allali, Philippe Ryvlin, Oliver Y. Ch\'en
Hugging Face Trending Papers
Jun 23

Uncertainty-Aware Longitudinal Forecasting of Alzheimer's Disease Progression Using Deep Learning

Longitudinal modelling of Alzheimer's disease progression is clinically useful only if it can describe not just the most likely next diagnosis, but how a patient may evolve over time and how reliable that forecast is. Most deep learning approaches reduce this problem to single-step classification, treating cognitively normal, mild cognitive impairment, and dementia as flat categories while providing limited insight into how uncertainty accumulates across future visits.