arXiv AI

The MAMA-MIA Challenge: Advancing Generalizability and Fairness in Breast MRI Tumor Segmentation and Treatment Response Prediction

arXiv:2603. 01250v2 Announce Type: replace-cross Abstract: Breast cancer is the most frequently diagnosed malignancy among women worldwide and a leading cause of cancer-related mortality.

arXiv AI
Sep 1

Subtraction-Based Tumor Segmentation and Lesion-Centered pCR Prediction for the MAMA-MIA Challenge

Team FME submitted a method for the MAMA-MIA Challenge that tackles primary tumor segmentation and pathological complete response (pCR) prediction using dynamic contrast‑enhanced breast MRI. For segmentation, they employed a five‑fold residual‑encoder nnU‑Net ensemble trained on the first post‑contrast minus pre‑contrast image, augmented with mirroring test‑time augmentation and largest‑connected‑component filtering, achieving a Dice score of 0.713 and a normalized Hausdorff distance of 0.099. For pCR prediction, they ensembled 25 pretrained 3D video classifiers on lesion‑centred crops from the pre‑contrast and first two post‑contrast volumes, reaching a balanced accuracy of 0.541 and an equalized‑odds disparity of 0.212, and ranked second in both tasks.

By Kai Geissler, Raphael Sch\"afer
arXiv Computer Vision
Sep 23

Neoadjuvant chemotherapy response prediction using pretreatment diffusion and contrast-enhanced magnetic resonance imaging with clinical variables

arXiv:2609.26105v1 Announce Type: cross Abstract: Prediction of pathological complete response before neoadjuvant chemotherapy may facilitate more tailored therapeutic planning for breast cancer pati...

By Pablo Garc\'ia Marcos, Paula Puerta Gonz\'alez, Guillermo Lorenzo, H\'ector G\'omez, Covadonga del Camino, Ad\'an Rodr\'iguez, Ignacio Pel\'aez, Angel Rio-Alvarez, V\'ictor M. Gonz\'alez
Hugging Face Trending Papers
Jul 21

MIRAGE: Multi-scale Lesion-Informed Representation with Auxiliary Guidance for MRI Contrast Enhancement

Inferring contrast enhancement from one pre-contrast breast MRI slice is underdetermined: post-contrast appearance contains physiological information that is not uniquely encoded in baseline anatomy. Optimizing only paired pixel fidelity can suppress uncertain lesion enhancement, whereas adversarial or stochastic generative objectives can favor realistic post-contrast appearance without guaranteeing patient-specific lesion fidelity.

arXiv AI
Aug 5

CorePath: A Breast-Specialized Pathology Foundation Model for Core Needle Biopsy Diagnosis and Risk-Controlled Report Generation

arXiv:2608. 03079v1 Announce Type: cross Abstract: Breast core needle biopsy (CNB) is central to breast cancer diagnosis yet remains challenging because limited tissue sampling, lesion heterogeneity, and subtle morphologic overlap can obscure subtype distinctions.

By Ting Yin, Danning Li, Chen Shu, Xiaoxia Yao, Boyu Fu, Yujing Chang, Tianyu Shi, Mengna Feng, Jie Chen, Jing Fu, Xiuli Xiao, Tianlin Li, Mumin Shao, Jiaxin Bi, Wenchuan Zhang, Xiaoyan Wu, Xiao Han, Zhang Zhang, Yuhao Yi, Hong Bu
arXiv Machine Learning
Aug 12

BreastMammo and DenseMammo: Benchmarks for Mammography Domain Generalization

arXiv:2608. 10271v1 Announce Type: cross Abstract: Breast density classification is a critical component of breast cancer risk assessment, yet AI models often struggle to generalize across clinical sites due to vendor-specific acquisition styles.

By Hongyi Pan, Gorkem Durak, Halil Ertugrul Aktas, Andrea Mia Bejar, Mustafa Ege Seker, Nebile Alibeyoglu, Rumeysa Guclu, Rana Gunoz Comert Bozkurt, Sibel Ozkan Gurdal, Neslihan Cabioglu, Beyza Ozcinar, Ravza Yilmaz, Vahit Ozmen, Erkin Aribal, Sukru Mehmet Erturk, Yalda Zafari, Mohamed Mabrok, Kayhan Batmanghelich, Mohammad Yaqub, Ziyue Xu, Ulas Bagci
Hugging Face Trending Papers
Jul 29

PRISM-Net: Patient-specific reference-guided inter-breast symmetry matching for three-class breast DCE-MRI classification

Breast DCE-MRI AI is increasingly being explored for breast-level classification of no-lesion, benign, and malignant findings, beyond conventional lesion-centered diagnosis. Within this broader diagnostic scope, however, patient-specific background variability remains a major source of imaging confounding across classification tasks.

arXiv Computer Vision
Aug 27

MAMA-FLUX.2: Image-to-Image Synthesis of Post-Contrast Breast DCE-MRI for the MAMA-SYNTH Challenge

The paper introduces MAMA-FLUX.2, a conditional latent flow‑matching model built on FLUX.2-Klein-4B, designed to synthesize post‑contrast breast DCE‑MRI from pre‑contrast images for the MAMA‑SYNTH challenge. It encodes the pre‑contrast image as spatial conditioning and predicts the flow field for the post‑contrast latent, adapting the pretrained model with LoRA fine‑tuning and a regional training objective that combines global flow matching, tumor‑region supervision, and stable foreground regularization. Ablation studies show that moderate tumor and stable‑foreground weighting improves the balance between image fidelity and tumor‑region accuracy, with the best configuration achieving a strong trade‑off using LoRA rank 64/64, MHA_max 25, λ_tumor 0.25, and λ_stable 0.1.

By Kamil Kwarciak, Marek Wodzinski