VGG16-MCA UNet is a hybrid neural network that combines an ImageNet‑pretrained VGG16 encoder with a decoder enhanced by a Multi‑Channel Attention module, trained using Focal Tversky loss to address class imbalance. The model was evaluated as a 2‑D, FLAIR‑only whole‑tumor segmenter on BraTS 2020 and LGG datasets, achieving a pixel‑level Dice of 95.10 % on BraTS and 88.32 % on LGG in a 5‑fold cross‑validation setting. Inference time is 66.32 ms per 256×256 slice on a single RTX 2060, only slightly slower than a VGG16‑UNet without attention.
whyItMatters":"The study provides a reproducible 2‑D FLAIR baseline for whole‑tumor segmentation, demonstrating high Dice scores and detailed reporting of training and evaluation protocols."
By Shubham Gajjar, Deep Joshi, Avi Poptani, Vishal Barot
arXiv:2603. 01250v2 Announce Type: replace-cross Abstract: Breast cancer is the most frequently diagnosed malignancy among women worldwide and a leading cause of cancer-related mortality.
By Lidia Garrucho, Smriti Joshi, Kaisar Kushibar, Richard Osuala, Maciej Bobowicz, Xavier Bargall\'o, Paulius Jaru\v{s}evi\v{c}ius, Kai Geissler, Raphael Sch\"afer, Muhammad Alberb, Tony Xu, Anne Martel, Daniel Sleiman, Navchetan Awasthi, Hadeel Awwad, Joan C. Vilanova, Robert Mart\'i, Daan Schouten, Jeong Hoon Lee, Mirabela Rusu, Eleonora Poeta, Luisa Vargas, Eliana Pastor, Maria A. Zuluaga, Jessica K\"achele, Dimitrios Bounias, Alexandra Ertl, Katarzyna Gwo\'zdziewicz, Maria-Laura Cosaka, Pasant M. Abo-Elhoda, Sara W. Tantawy, Shorouq S. Sakrana, Norhan O. Shawky-Abdelfatah, Amr Muhammad Abdo-Salem, Androniki Kozana, Eugen Divjak, Gordana Ivanac, Katerina Nikiforaki, Michail E. Klontzas, Rosa Garc\'ia-Dosd\'a, Meltem Gulsun-Akpinar, O\u{g}uz Lafc{\i}, Carlos Mart\'in-Isla, Oliver D\'iaz, Laura Igual, Karim Lekadir
arXiv:2607. 19137v1 Announce Type: cross Abstract: Inferring contrast enhancement from one pre-contrast breast MRI slice is underdetermined: post-contrast appearance contains physiological information that is not uniquely encoded in baseline anatomy.
By Andrea Borghesi, Xin Wang, Jonas Teuwen, George Yiasemis
The paper reports the submissions of team nucli to the HECKTOR 2026 challenge, which evaluates machine learning methods for head‑and‑neck cancer imaging. The team used self‑supervised pre‑trained encoders, training a 2D DINOv2 encoder on PET scans and combining a DynUNet with a SwinUNETR for segmentation, achieving a mean Dice of 0.5409. For TN staging, they fused geometric features from segmentation masks with PET‑DINOv2‑MIPs deep features via logistic regression, obtaining balanced accuracies of 0.3962 (T‑stage) and 0.6432 (N‑stage). For recurrence‑free survival prognosis, they fine‑tuned the PET‑DINOv2‑MIPs ViT‑S encoder with an MLP head under a CoxPH loss, achieving a Harrell's C‑index of 0.6577 and a weighted challenge score of 0.5802.
arXiv:2610.09784v1 Announce Type: new
Abstract: Reliable liver segmentation in contrast-enhanced MRI is essential for quantitative hepatic assessment, treatment planning, and longitudinal disease mon...
By Ruoshi Xu, Mingqi Gao, Shengda Luo, Jingkun Chen
Inferring contrast enhancement from one pre-contrast breast MRI slice is underdetermined: post-contrast appearance contains physiological information that is not uniquely encoded in baseline anatomy. Optimizing only paired pixel fidelity can suppress uncertain lesion enhancement, whereas adversarial or stochastic generative objectives can favor realistic post-contrast appearance without guaranteeing patient-specific lesion fidelity.
arXiv:2511. 15968v2 Announce Type: replace-cross Abstract: External validation of breast ultrasound segmentation models remains limited because internal train--test splits do not capture domain shifts across imaging systems, acquisition protocols, and patient populations.
By Jingru Zhang, Saed Moradi, Ashirbani Saha
The paper introduces MAMA-FLUX.2, a conditional latent flow‑matching model built on FLUX.2-Klein-4B, designed to synthesize post‑contrast breast DCE‑MRI from pre‑contrast images for the MAMA‑SYNTH challenge. It encodes the pre‑contrast image as spatial conditioning and predicts the flow field for the post‑contrast latent, adapting the pretrained model with LoRA fine‑tuning and a regional training objective that combines global flow matching, tumor‑region supervision, and stable foreground regularization. Ablation studies show that moderate tumor and stable‑foreground weighting improves the balance between image fidelity and tumor‑region accuracy, with the best configuration achieving a strong trade‑off using LoRA rank 64/64, MHA_max 25, λ_tumor 0.25, and λ_stable 0.1.
By Kamil Kwarciak, Marek Wodzinski
The paper introduces SWIFT, a Swin V2‑based model pretrained on 10,444 3D CT volumes and fine‑tuned for rectal cancer segmentation on T2‑weighted MRI. Four configurations—full fine‑tuning (SWIFT), decoder compression (SWIFTe), low‑rank adaptation (SWIFTe‑LoRA), and a LoRA‑decoder ensemble (SWIFTe‑LDE4)—were evaluated on 247 cases, showing that SWIFTe reduces parameters by 70.1% while improving tumor detection and radiomic agreement. The study also demonstrates a trade‑off between detection and boundary agreement, and highlights that SWIFTe‑LDE4 achieves the lowest calibration errors after temperature scaling.
By Aneesh Rangnekar, Jorge Tapias Gomez, Joseph O Deasy, Harini Veeraraghavan
The paper introduces TopKSigLIP, a vision‑language model tailored for mammography that tackles two key challenges: high‑resolution imaging and homogeneous radiology reports. It replaces standard CLIP training with a TopK‑Patch module that selects sparse high‑resolution patches likely to contain lesions, and a Sup‑sigmoid loss that uses soft labels from structured data instead of contrastive loss. TopKSigLIP outperforms existing open‑source mammography and general medical VLMs on zero‑shot tasks such as density assessment, BI‑RADS classification, finding subtyping, and cancer prediction, while also providing better lesion localization than Grad‑CAM.
By Young Seok Jeon, Beatrice Brown-Mulry, Rohan Satya Isaac, Anjana Dissanayaka, Theo Dapamede, Mohammadreza Chavoshi, Judy Gichoya, Hari Trivedi
The study examines how LoRA adaptation of four Vision Foundation Models—DINOv3, SigLIP2, MerMED-FM, and BiomedCLIP—affects brain MRI tasks. Despite achieving similar segmentation accuracy (mean Dice 78‑81%), the models exhibit distinct internal dynamics, with early‑to‑mid layers being most crucial for segmentation. Restricting LoRA to these layers yields comparable performance while mitigating negative impacts on Alzheimer’s disease classification.
By Cecilia Diana-Albelda, Fiona Kekwick, Raghav Mehta, Aleksandra Kulbaka, Paul M. Matthews, Jesus Bescos, \'Alvaro Garc\'ia-Mart\'in, Wenjia Bai, Bernhard Kainz
CMRVision is a cardiac magnetic resonance (CMR) foundation model trained with DINOv3-style self‑supervised learning on 36 million multi‑center, multi‑sequence CMR images. It outperforms prior natural‑image, medical‑image, supervised, and CMR baselines on multi‑task segmentation (cine, LGE, mapping) and cine view classification, achieving Dice scores of 0.940–0.967 for LV and 0.855–0.905 for myocardium, and a zero‑shot Dice of 0.692 on unseen LGE long‑axis views. The model demonstrates robust cross‑view generalization and highest average accuracy (0.906) for cine view classification.
By Athira J. Jacob, Puneet Sharma, Daniel Rueckert