arXiv AI

Subtraction-Based Tumor Segmentation and Lesion-Centered pCR Prediction for the MAMA-MIA Challenge

Team FME submitted a method for the MAMA-MIA Challenge that tackles primary tumor segmentation and pathological complete response (pCR) prediction using dynamic contrast‑enhanced breast MRI. For segmentation, they employed a five‑fold residual‑encoder nnU‑Net ensemble trained on the first post‑contrast minus pre‑contrast image, augmented with mirroring test‑time augmentation and largest‑connected‑component filtering, achieving a Dice score of 0.713 and a normalized Hausdorff distance of 0.099. For pCR prediction, they ensembled 25 pretrained 3D video classifiers on lesion‑centred crops from the pre‑contrast and first two post‑contrast volumes, reaching a balanced accuracy of 0.541 and an equalized‑odds disparity of 0.212, and ranked second in both tasks.

arXiv AI
Jun 19

The MAMA-MIA Challenge: Advancing Generalizability and Fairness in Breast MRI Tumor Segmentation and Treatment Response Prediction

arXiv:2603. 01250v2 Announce Type: replace-cross Abstract: Breast cancer is the most frequently diagnosed malignancy among women worldwide and a leading cause of cancer-related mortality.

By Lidia Garrucho, Smriti Joshi, Kaisar Kushibar, Richard Osuala, Maciej Bobowicz, Xavier Bargall\'o, Paulius Jaru\v{s}evi\v{c}ius, Kai Geissler, Raphael Sch\"afer, Muhammad Alberb, Tony Xu, Anne Martel, Daniel Sleiman, Navchetan Awasthi, Hadeel Awwad, Joan C. Vilanova, Robert Mart\'i, Daan Schouten, Jeong Hoon Lee, Mirabela Rusu, Eleonora Poeta, Luisa Vargas, Eliana Pastor, Maria A. Zuluaga, Jessica K\"achele, Dimitrios Bounias, Alexandra Ertl, Katarzyna Gwo\'zdziewicz, Maria-Laura Cosaka, Pasant M. Abo-Elhoda, Sara W. Tantawy, Shorouq S. Sakrana, Norhan O. Shawky-Abdelfatah, Amr Muhammad Abdo-Salem, Androniki Kozana, Eugen Divjak, Gordana Ivanac, Katerina Nikiforaki, Michail E. Klontzas, Rosa Garc\'ia-Dosd\'a, Meltem Gulsun-Akpinar, O\u{g}uz Lafc{\i}, Carlos Mart\'in-Isla, Oliver D\'iaz, Laura Igual, Karim Lekadir
Hugging Face Trending Papers
Jul 21

MIRAGE: Multi-scale Lesion-Informed Representation with Auxiliary Guidance for MRI Contrast Enhancement

Inferring contrast enhancement from one pre-contrast breast MRI slice is underdetermined: post-contrast appearance contains physiological information that is not uniquely encoded in baseline anatomy. Optimizing only paired pixel fidelity can suppress uncertain lesion enhancement, whereas adversarial or stochastic generative objectives can favor realistic post-contrast appearance without guaranteeing patient-specific lesion fidelity.

arXiv Computer Vision
Aug 27

MAMA-FLUX.2: Image-to-Image Synthesis of Post-Contrast Breast DCE-MRI for the MAMA-SYNTH Challenge

The paper introduces MAMA-FLUX.2, a conditional latent flow‑matching model built on FLUX.2-Klein-4B, designed to synthesize post‑contrast breast DCE‑MRI from pre‑contrast images for the MAMA‑SYNTH challenge. It encodes the pre‑contrast image as spatial conditioning and predicts the flow field for the post‑contrast latent, adapting the pretrained model with LoRA fine‑tuning and a regional training objective that combines global flow matching, tumor‑region supervision, and stable foreground regularization. Ablation studies show that moderate tumor and stable‑foreground weighting improves the balance between image fidelity and tumor‑region accuracy, with the best configuration achieving a strong trade‑off using LoRA rank 64/64, MHA_max 25, λ_tumor 0.25, and λ_stable 0.1.

By Kamil Kwarciak, Marek Wodzinski
arXiv Computer Vision
Aug 28

Parameter-Efficient pretrained-CT-to-MRI Transfer for Rectal Cancer Segmentation: Performance-Calibration Trade-offs

The paper introduces SWIFT, a Swin V2‑based model pretrained on 10,444 3D CT volumes and fine‑tuned for rectal cancer segmentation on T2‑weighted MRI. Four configurations—full fine‑tuning (SWIFT), decoder compression (SWIFTe), low‑rank adaptation (SWIFTe‑LoRA), and a LoRA‑decoder ensemble (SWIFTe‑LDE4)—were evaluated on 247 cases, showing that SWIFTe reduces parameters by 70.1% while improving tumor detection and radiomic agreement. The study also demonstrates a trade‑off between detection and boundary agreement, and highlights that SWIFTe‑LDE4 achieves the lowest calibration errors after temperature scaling.

By Aneesh Rangnekar, Jorge Tapias Gomez, Joseph O Deasy, Harini Veeraraghavan
arXiv Computer Vision
Sep 4

Solving the Needle-in-a-Haystack Problem in Mammography Vision-Language Model with Differentiable Subset Sampling

The paper introduces TopKSigLIP, a vision‑language model tailored for mammography that tackles two key challenges: high‑resolution imaging and homogeneous radiology reports. It replaces standard CLIP training with a TopK‑Patch module that selects sparse high‑resolution patches likely to contain lesions, and a Sup‑sigmoid loss that uses soft labels from structured data instead of contrastive loss. TopKSigLIP outperforms existing open‑source mammography and general medical VLMs on zero‑shot tasks such as density assessment, BI‑RADS classification, finding subtyping, and cancer prediction, while also providing better lesion localization than Grad‑CAM.

By Young Seok Jeon, Beatrice Brown-Mulry, Rohan Satya Isaac, Anjana Dissanayaka, Theo Dapamede, Mohammadreza Chavoshi, Judy Gichoya, Hari Trivedi
arXiv Computer Vision
Sep 2

CMRVision: A Foundation Model for Cardiac MR Image Analysis

CMRVision is a cardiac magnetic resonance (CMR) foundation model trained with DINOv3-style self‑supervised learning on 36 million multi‑center, multi‑sequence CMR images. It outperforms prior natural‑image, medical‑image, supervised, and CMR baselines on multi‑task segmentation (cine, LGE, mapping) and cine view classification, achieving Dice scores of 0.940–0.967 for LV and 0.855–0.905 for myocardium, and a zero‑shot Dice of 0.692 on unseen LGE long‑axis views. The model demonstrates robust cross‑view generalization and highest average accuracy (0.906) for cine view classification.

By Athira J. Jacob, Puneet Sharma, Daniel Rueckert
arXiv AI
Aug 18

DualMiT-Net: Local-Global Transformer-Convolutional Fusion for Breast Mass Segmentation in Mammographic Regions of Interest

arXiv:2608. 15019v1 Announce Type: cross Abstract: Breast mass segmentation is an important step in computer-aided mammography, but it remains difficult because masses can have low contrast, irregular shapes, and boundaries that blend with surrounding breast tissue.

By Alibek Kamiluly, Milana Muratova, Yash Patel, Fan Li
arXiv AI
Sep 10

Deep Learning-Based Segmentation of Peritoneal Cancer Index Regions from CT Imaging

arXiv:2604.27697v2 Announce Type: replace-cross Abstract: Peritoneal metastases (PM) are staged using the surgically determined Peritoneal Cancer Index (sPCI), which requires invasive laparoscopic as...

By Pieter C. Gort, Lotte J. S. Fleurkens-Ewals, Lenah D. Kampmeijer, Anna F. van Herwijnen, Marion W. Tops-Welten, Cris H. B. Claessens, Joost Nederend, Ignace H. J. T. De Hingh, Max J. Lahaye, Misha D. P. Luyer, Fons van der Sommen
arXiv Machine Learning
2d ago

NeuroTS-Net: Multi-Class Semantic Segmentation of Pediatric Brain Tumors in Multi-Modal MRI

NeuroTS-Net is a 3‑D encoder‑decoder CNN designed for multi‑class semantic segmentation of pediatric brain tumors in multi‑modal MRI. It uses a dual‑scale raw‑detail stream, adaptive low‑resolution context selection, and detail‑preserving multipath downsampling to maintain fine intensity and boundary information while modeling broader tumor context. Trained on the BraTS 2026 pediatric dataset, it outperformed nnU‑Net and MedNeXt, achieving Dice scores of 0.938/0.937 on internal validation and 0.927/0.926 on the official challenge set.

By Darius Peteleaza, Razvan-Gabriel Dumitru, Bogdan Neamtu, Arpad Gellert, Mariana Sandu, Claudiu Matei
arXiv AI
Aug 28

Pixel Wised Lesion Prediction on COVID-19 CT Imagery: A Comparative Analysis of Automated Image Segmentation Architectures

The study evaluates four deep‑learning segmentation architectures—Unet, PSPNet, Linknet, and FPN—paired with six pre‑trained encoders to predict COVID‑19 lesions in CT images. Experiments on three COVID‑19 CT datasets show high accuracy, achieving a maximum binary F1‑score of 98% and multi‑class F1‑scores of 75% and 77%. The work aims to provide a standardized performance benchmark for medical image segmentation and a reference for other imaging scenarios.

By Sarmad Khan, Basim Azam, Arslan Shaukat