arXiv AI

PatientWM: Towards Generalizable Clinical World Models via Unified Patient States

arXiv AI
Sep 10

NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

NOAH is a generative transformer that learns the full multimodal patient journey by integrating bidirectional time and a variational latent space. Trained on over 559 million clinical events from 431,000 hospital visits, it processes medical images, time‑series, numeric signals, categorical events, and both structured and unstructured records. The model supports autoregressive forecasting, zero‑shot classification, and counterfactual intervention simulation, yielding strong performance on clinical outcomes, ICD chapters, comorbidities, and time‑to‑event prediction.

By Tobias Susetzky, Raphael Rehms, Dmitrii Seletkov, \"Ozg\"un Turgut, Michelle Espranita Liman, Lisa Steinhelfer, Rickmer Braren, Daniel Rueckert
Hugging Face Trending Papers
Sep 8

NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

NOAH is a generative transformer that models the entire multimodal patient journey by integrating bidirectional time and a variational latent space to capture continuous, stochastic clinical trajectories. Trained on over 559 million events from 431,000 hospital visits, it processes medical images, time‑series, numeric signals, categorical events, and both structured and unstructured records. The model supports autoregressive forecasting, zero‑shot classification, and counterfactual simulations, yielding strong predictive performance across 15 ICD chapters, 29 comorbidities, and time‑to‑event outcomes.

arXiv AI
Jul 22

Biological Amnesia in ICU Time-Series Prediction: A Drift-Adaptive Two-Stream Architecture with Temporal Retrieval

arXiv:2607. 19020v1 Announce Type: cross Abstract: Background: Clinical decision support systems degrade silently as treatment protocols evolve, yet standard adaptation methods treat models as monolithic blocks, unable to distinguish stable patient physiology from shifting institutional practice.

By Fatema Ferdous Tamanna, K. M. Merajul Arefin, Md. Abdul Masud
Hugging Face Trending Papers
Aug 13

Intervention-Aware Clinical World Model for Post-Op Outcome Forecasting in Cardiology

Many clinical prediction models treat post-intervention outcomes as a one-step mapping from baseline measurements to a future endpoint. However, recovery after a procedure often unfolds as an irregular trajectory: clinical observations, medication changes, repeat interventions, and physiological measurements are recorded asynchronously and can change risk assessment over time.

arXiv Machine Learning
Jul 20

LLM4EHR: Aligning Clinical Time Series with Medical Event Sequences via Large Language Models

arXiv:2607. 15447v1 Announce Type: new Abstract: Recent research in clinical machine learning, focusing on outcome predictions in intensive care unit (ICU), has shifted from bespoke supervised models to foundation models, utilising modern representation learning methods.

By Jingteng Li, Alexander Capstick, Louise Rigny, Iona Biggart, Neil J Sebire, Payam Barnaghi
arXiv Machine Learning
Aug 4

EHR2Path: Comprehensive Pathway-Level Modeling of Longitudinal Patient Trajectories from Multimodal Electronic Health Records

arXiv:2506. 04831v3 Announce Type: replace Abstract: Forecasting how a patient's condition is likely to evolve, including possible deterioration, recovery, treatment needs, and care transitions, could support more proactive and personalized care, but requires modeling heterogeneous and longitudinal electronic health record (EHR) data.

By Chantal Pellegrini, Ege \"Ozsoy, David Bani-Harouni, Matthias Keicher, Nassir Navab