arXiv Machine Learning

Confidence-Gated Cloud-Edge Cascade Triage via Variational Risk Minimization for Medical Imaging

The paper introduces Variational Risk Minimization (VRM), a distillation framework that treats large vision‑language model (LVLM) report variants as Monte Carlo samples of latent clinical interpretations. VRM learns from a variationally marginalized teacher distribution, providing uncertainty‑aware supervision even when modalities are missing, and outperforms fine‑tuning baselines while improving calibration. In a compact edge‑student setup, a confidence‑gated cascade achieves an AUC of 0.941 at 103 ms latency with only 20.3 % cloud escalation, offering a clear reliability‑latency trade‑off for cloud‑edge medical imaging workflows.

arXiv Machine Learning
Aug 18

Beyond Boundary Noise: Aggregated Aleatoric Uncertainty Fails to Capture Presence Ambiguity in 3D Lung Nodule Segmentation

arXiv:2608. 14766v1 Announce Type: cross Abstract: Uncertainty estimation is critical for the safe clinical deployment of deep learning in medical image segmentation, with aleatoric uncertainty theoretically designed to capture irreducible data ambiguity.

By Simon Baur, Arne Schernich, Ekin B\"oke, Wojciech Samek, Jackie Ma
arXiv AI
Jul 7

CONFLUX: A Latent Diusion Model for 3D Chest-CT Synthesis with RL Post-Training

arXiv:2607. 02998v1 Announce Type: cross Abstract: Controllable generative models of 3D medical images can synthesize volumes with specified clinical attributes, but this demands samples that are simultaneously high-fidelity, natively 3D, and faithful to the requested conditioning.

By Max Van Puyvelde, Halil Ibrahim Gulluk, Wim Van Criekinge, Olivier Gevaert
arXiv AI
Jul 8

CONFLUX: A Latent Diffusion Model for 3D Chest-CT Synthesis with RL Post-Training

arXiv:2607. 02998v2 Announce Type: replace-cross Abstract: Controllable generative models of 3D medical images can synthesize volumes with specified clinical attributes, but this demands samples that are simultaneously high-fidelity, natively 3D, and faithful to the requested conditioning.

By Max Van Puyvelde, Halil Ibrahim Gulluk, Wim Van Criekinge, Olivier Gevaert
arXiv Computer Vision
Aug 21

CalcSeg: Confidence-aware 3D Latent Context Curriculum Learning For Myocardial Scar Segmentation From Single-Stack LGE-CMRs

arXiv:2608. 20305v1 Announce Type: new Abstract: Myocardial scar segmentation from single-stack late gadolinium-enhanced cardiac magnetic resonance (LGE-CMR) imaging has been a longstanding and clinically important challenge, particularly in the presence of low tissue contrast, diffuse, and small scar regions.

By Nivetha Jayakumar, Hannah Kim, Amit R. Patel, Miaomiao Zhang
arXiv Machine Learning
5d ago

Data-Driven Priors for Uncertainty-Aware Risk Prediction of Clinical Deterioration using Multimodal Data

The paper introduces MedCertAIn, a framework that uses data‑driven priors to enhance uncertainty estimation in multimodal clinical models. By integrating cross‑modal similarity and modality‑specific corruptions into neural network priors, the authors improve predictive performance and selective prediction for in‑hospital mortality risk using MIMIC‑IV and MIMIC‑CXR data. The results demonstrate competitive accuracy and notable gains over deterministic and stochastic baselines, underscoring the potential of such priors for reliable, uncertainty‑aware clinical decision support.

By L. Juli\'an Lechuga L\'opez, Tim G. J. Rudner, Farah E. Shamout
arXiv Computer Vision
Sep 7

Compositional Reward Models for Conditional Medical Image Generation

The paper introduces PRISM, a Compositional Reward Model framework that decomposes image quality into multiple verifier‑grounded stages for conditional medical image generation. By assigning distinct rewards for fine‑to‑coarse properties—such as intensity, texture, structural alignment, and semantic fidelity—and combining them via a Hierarchical Constrained Propagation mechanism, PRISM addresses shortcomings of single‑scalar reward approaches. Experiments on PanNuke, CeDeM, and ISIC datasets show that data generated with PRISM improves downstream model performance, achieving higher mDice, lower MRE, and increased F1 scores compared to baseline methods.

By Aayush Kumar Tyagi, Prathosh A. P., Mausam