arXiv AI

A Comparative Explainability Framework for DeBERTa-v3 in Zero-Shot Medical Abstract Classification

The paper introduces a comparative explainability framework for auditing DeBERTa‑v3 in zero‑shot medical abstract classification. It evaluates five explanation methods—SHAP, LIME, occlusion, Input × Gradient, and Attention × Gradient—using a natural language inference engine on a balanced corpus of 1,000 abstracts per diagnostic category. The study finds that explanatory stability aligns with predictive certainty, identifies three systemic failure mechanisms, and recommends combining multiple explanation methods and quantitative agreement metrics for transformer‑based medical text classifiers.

arXiv AI
Jul 28

Explaining BiomedCLIP with Weighted Banzhaf Interactions Supported by Tree-Gram Parsing

arXiv:2607. 23368v1 Announce Type: cross Abstract: Vision-Language Models (VLMs) are demonstrating significant capabilities in medical tasks like radiology analysis, yet providing faithful and interpretable explanations remains a key consideration for their responsible deployment in clinical settings.

By Jakub Rymarski (University of Warsaw, Poland), Adam Rempa{\l}a (University of Warsaw, Poland), Bart{\l}omiej Sobieski (University of Warsaw, Poland), Przemys{\l}aw Biecek (University of Warsaw, Poland)
arXiv Machine Learning
Sep 7

SMILE: Self-Explainable Multimodal Information Bottleneck for Medical Diagnosis

The paper introduces SMILE, a self‑explainable multimodal information bottleneck framework for medical diagnosis. It jointly optimizes predictive accuracy and modality‑specific explainability by selecting the most informative elements within each data modality. Experiments on diverse medical datasets show strong diagnostic performance, including a 9.1‑percentage‑point accuracy gain on the iCTCF dataset, and provide transparent, modality‑aware explanations that enhance both explainability and generalization.

By Yuqing Yang, Alexander Schmatz, Zhaozhao Ma, Changkyu Choi, Robert Jenssen, Shujian Yu
arXiv AI
Jul 21

Retrieval-Augmented Interpretable Learning: Towards Task-Specific Zero-Shot Models in Healthcare

arXiv:2607. 17508v1 Announce Type: cross Abstract: We introduce Retrieval-Augmented Interpretable Learning (RAIL), a probabilistic meta-learning framework for zero-shot generation of task-specific interpretable models that synthesizes coefficient-space structure from natural-language task descriptions and a memory of previously learned task-specific predictors.

By Sazan Mahbub, Caleb Ellington, Zhiyuan Li, Yixin Yang, Souvik Kundu, Ben Lengerich, Eric P. Xing
arXiv AI
Jun 29

From Black-Box to Clinical Insight: A Multi-Stage Explainable Framework for Speech-Based Cognitive Impairment Detection

arXiv:2606. 27973v1 Announce Type: cross Abstract: Speech-based cognitive impairment detection offers a noninvasive, accessible alternative to costly biomarker assays, yet transformer-based models remain clinically uninterpretable.

By Yasaman Haghbin, Sina Rashidi, Ali Zolnour, Fatemeh Taherinezhad, Ali Fartoot, Hossein Azadmaleki, James M Noble, Maryam Dadkhah, Maryam Zolnoori
arXiv AI
Aug 18

DiagnosisArena: Benchmarking Diagnostic Reasoning for Large Language Models

arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.

By Yakun Zhu, Zhongzhen Huang, Linjie Mu, Yutong Huang, Wei Nie, Jiaji Liu, Shaoting Zhang, Pengfei Liu, Xiaofan Zhang
arXiv AI
Jul 20

Perception-Aligned AI Outputs: End-to-End Visual Prediction for Uncertainty Communication in Clinical Decision-Making

arXiv:2205. 04599v2 Announce Type: replace-cross Abstract: Explainable Artificial Intelligence (XAI) is essential for trustworthy AI in healthcare, yet many existing methods rely on technical explanations that are difficult for clinicians and patients to interpret.

By Mohammad Eslami, Solale Tabarestani, Saber Kazeminasab, Ehsan Adeli, Glyn Elwyn, Tobias Elze, Mengyu Wang, Nazlee Zebardast, Lucia Sobrin, Nassir Navab, Daniel Shu Wei Ting, Malek Adjouadi