SEG-SAM is a unified medical image segmentation model that builds on the Segment Anything Model (SAM) by integrating semantic medical knowledge. It introduces a semantic‑aware decoder separate from SAM’s original decoder to handle both semantic segmentation of prompted objects and classification of unprompted objects. The model also incorporates key medical category characteristics from large language models via a text‑to‑vision semantic module and uses a cross‑mask spatial alignment strategy to improve overlap between predictions, achieving superior performance over existing SAM‑based and task‑specific methods.
By Shuangping Huang, Hao Liang, Qingfeng Wang, Chulong Zhong, Zijian Zhou, Miaojing Shi
arXiv:2608. 20229v1 Announce Type: cross Abstract: Anatomically plausible segmentation remains challenging because of low contrast, ambiguous boundaries, and modality-specific artifacts.
By Mosharof Hossain, Md Rabiul Islam, Limon Halder, Erchin Serpedin, Md Kamrul Hasan
arXiv:2505.03380v2 Announce Type: replace
Abstract: Accurate delineation of tumors and surrounding organs-at-risk is essential for radiotherapy, surgery and treatment response assessment, yet remains...
By Haonan Wang, Jiaji Mao, Lehan Wang, Qixiang Zhang, Marawan Elbatel, Yi Qin, Huijun Hu, Baoxun Li, Wenhui Deng, Weifeng Qin, Hongrui Li, Jialin Liang, Jun Shen, Xiaomeng Li
arXiv:2608.23745v1 Announce Type: cross
Abstract: Accurate brain tumor segmentation from magnetic resonance imaging (MRI) is essential for diagnosis, treatment planning, surgical guidance, and diseas...
By Mohammad Mahdi Danesh Pajouh, Sara Saeedi
arXiv:2609.37283v1 Announce Type: new
Abstract: Medical multimodal large language models (MLLMs) are increasingly expected not only to answer clinical questions, but also to localize the visual evide...
By Xuyang Cao, Enyou Liu, Jun Zhao, Zhuoyun Liu, Jintao Fei, Leo
The paper introduces FreNet, a feature reconfiguration framework that incorporates visual priors for medical lesion segmentation. FreNet performs pixel‑level reconfiguration before encoding using an Implicit Prior Neural Network (IPNN) that leverages SAM, and feature‑level reconfiguration during encoding via a Dual‑domain Feature Reconfiguration (DFR) module, which includes a Frequency Decoupling Module (FDM) and a Spatial Localization Module (SLM). Experiments on nine benchmarks across three imaging modalities show that FreNet outperforms state‑of‑the‑art methods, achieving a 5.0% Dice improvement over the best baseline on the ETIS dataset and a 7.2% improvement over SAM.
By Yinan Liu, Jiankang Hong, Zhen Gao, Ye Lu
arXiv:2607. 14328v1 Announce Type: cross Abstract: In proton therapy planning, respiratory-gated non-contrast CT (NCCT) is commonly used for lesion segmentation; however, accurate delineation remains challenging due to low lesion-to-background contrast.
By San Lee, Nalee Kim, Jeong Il Yu, Hee Chul Park, Boah Kim
Abdominal organ segmentation is essential in modern medical applications. While existing deep learning approaches demonstrate promising performance, their heavy reliance on large-scale image data rais...
Feature Reconfiguration With Visual Prior for Medical Lesion Segmentation proposes FreNet, a framework that reconfigures images and features before and during encoding to improve lesion segmentation. It introduces an Implicit Prior Neural Network that uses a visual prior from SAM to suppress background responses, and a Dual-domain Feature Reconfiguration module that decouples features in frequency and spatial domains to better handle diverse lesion morphology. Experiments on nine benchmarks across three imaging modalities show FreNet outperforms state‑of‑the‑art methods, achieving a 5.0% Dice improvement over the best prior method on the ETIS dataset.
arXiv:2610.29090v1 Announce Type: new
Abstract: Abdominal organ segmentation is essential in modern medical applications. While existing deep learning approaches demonstrate promising performance, th...
By Derong Yu, Guoyan Zheng
The paper introduces MSM‑Seg, a dual‑memory segmentation framework for 3D multi‑modal brain tumor segmentation. It combines a modality‑and‑slice memory attention module to capture cross‑modal and spatial‑slice dependencies, a multi‑scale category‑agnostic prompt encoder for whole‑tumor guidance, and a modality‑adaptive fusion decoder to integrate complementary decoding information. Experiments on various MRI datasets show that MSM‑Seg surpasses state‑of‑the‑art methods for metastases and glioma tumor segmentation.
By Yuxiang Luo, Qing Xu, Hai Huang, Yuqi Ouyang, Xiangjian He, Zhen Chen, Wenting Duan, Jiebo Luo
arXiv:2606. 04705v1 Announce Type: cross Abstract: Semantic segmentation in medical imaging is a critical yet challenging task due to data scarcity and high variability across modalities.
By Amirhossein Movahedisefat, Amirreza Fateh, Mohammad Reza Mohammadi