The paper introduces FreNet, a feature reconfiguration framework that incorporates visual priors for medical lesion segmentation. FreNet performs pixel‑level reconfiguration before encoding using an Implicit Prior Neural Network (IPNN) that leverages SAM, and feature‑level reconfiguration during encoding via a Dual‑domain Feature Reconfiguration (DFR) module, which includes a Frequency Decoupling Module (FDM) and a Spatial Localization Module (SLM). Experiments on nine benchmarks across three imaging modalities show that FreNet outperforms state‑of‑the‑art methods, achieving a 5.0% Dice improvement over the best baseline on the ETIS dataset and a 7.2% improvement over SAM.
By Yinan Liu, Jiankang Hong, Zhen Gao, Ye Lu
The paper introduces Spatial‑FAD, a few‑shot medical anomaly detection framework that fuses Vision‑Language Model (CLIP) semantics with spatial priors from Vision Foundation Models (DINO). A VFM‑enhanced adapter injects structural affinity into CLIP features, while a sliding‑window aggregation produces high‑resolution embeddings for finer lesion localization. Prototype‑enhanced support memory further improves efficiency and performance, yielding significant gains on Liver CT, Retinal OCT, and Brain MRI datasets, notably an 11.4% Dice improvement in 4‑shot scenarios.
By Juzheng Miao, Yuchen Yuan, Cheng Chen, Pheng-Ann Heng
InstEditSeg is a generative framework that treats medical segmentation as an instruction-driven image editing task. Instead of producing binary masks, it renders a color-coded overlay on the original image guided by textual instructions, leveraging latent diffusion models to align with natural image distributions and reduce domain gaps. The method incorporates a DINOv3 visual encoder and a multi-scale feature pyramid fused into the diffusion U‑Net, and uses a dual‑branch classifier‑free guidance strategy to lower inference cost, achieving competitive accuracy on polyp and skin lesion datasets while improving cross‑domain generalization and multi‑lesion segmentation.
By Ziquan Liu, Zhewei Zhu, Xuyang Shi
arXiv:2610.00279v1 Announce Type: new
Abstract: The segmentation of anatomical structures in medical images and particularly in MRI scans, is essential for clinical diagnosis and monitoring disease p...
By Eirini Cholopoulou, Dimitrios E. Diamantis, Dimitris K. Iakovidis
SAM-DCE is a framework that adapts the Segment Anything Model (SAM) for fully automatic, prompt‑free medical image segmentation. It introduces Spatial Representation Compensation (SRC) to recover fine anatomical details from intermediate Vision Transformer features and Semantic Token Calibration (STC) to enhance the consistency of foreground mask tokens. By refining spatial and semantic representations before using SAM’s original token‑to‑mask mechanism, SAM‑DCE achieves superior performance on the Synapse multi‑organ CT segmentation dataset, with a mean Dice score of 83.86% and an HD95 of 16.04 mm, outperforming several CNN, Transformer, and SAM baselines.
By Yingzhen Hu, Yiheng Zhong, Aijing Yang, Georges El Fakhri, Xiaofeng Liu
Accurate medical image interpolation and anatomical structure segmentation are fundamental for computer-aided diagnosis and treatment planning. Anisotropic medical volumes with sparse through-plane sampling often suffer from structural discontinuity and boundary blur, hindering reliable clinical image analysis.
Abdominal organ segmentation is essential in modern medical applications. While existing deep learning approaches demonstrate promising performance, their heavy reliance on large-scale image data rais...
The paper introduces DPIF, a plug‑and‑play dual‑path interaction framework that can be integrated with any encoder‑decoder segmentation network. DPIF aligns cross‑view distributions using Sinkhorn optimal transport, decouples features via conditional mutual information to transfer knowledge within shared semantic spaces, and applies persistent homology‑based topological regularization to encode anatomical invariants. Experiments on a private echocardiography dataset and two public datasets show that DPIF‑enhanced models outperform single‑view baselines and achieve comparable performance to full‑data single‑view models while using only 40–60% of the data.
By Shuhuan Wang, Yuanyuan Cui, Pengju Wang, Huimin Guo, Ling Yue, Yin Gu, Yanchao Zhang, Wei Feng, Yunhe Liu, Wei Qian, Mingjun Xu, Shuang Liu, He Ma
Medical image segmentation relies on the ability of encoder-decoder architectures to translate rich feature representations into accurate pixel-level predictions under challenging conditions such as low contrast, structural ambiguity, and scale variability. While recent advances in large-scale pretraining and transformer-based encoders have substantially improved feature extraction, segmentation accuracy remains constrained by decoder design, particularly in terms of cross-scale alignment, contextual integration, and boundary preservation.
arXiv:2608. 20229v1 Announce Type: cross Abstract: Anatomically plausible segmentation remains challenging because of low contrast, ambiguous boundaries, and modality-specific artifacts.
By Mosharof Hossain, Md Rabiul Islam, Limon Halder, Erchin Serpedin, Md Kamrul Hasan
The paper introduces SSS, a semi‑supervised framework that builds on the Vision Foundation Model SAM‑2 to improve medical image segmentation. It combines a weak‑to‑strong consistency regularization with a Discriminative Feature Enhancement mechanism and a prompt generator that uses Physical Constraints with a Sliding Window to supply prompts for unlabeled data. Experiments on the ACDC and BHSD datasets show that SSS outperforms prior methods, achieving a 53.15 Dice score on BHSD, a +3.65 improvement over the state of the art.
By Hongjie Zhu, Xiwei Liu, Rundong Xue, Zeyu Zhang, Yong Xu, Daji Ergu, Ying Cai, Yang Zhao
The study evaluates four deep‑learning segmentation architectures—Unet, PSPNet, Linknet, and FPN—paired with six pre‑trained encoders to predict COVID‑19 lesions in CT images. Experiments on three COVID‑19 CT datasets show high accuracy, achieving a maximum binary F1‑score of 98% and multi‑class F1‑scores of 75% and 77%. The work aims to provide a standardized performance benchmark for medical image segmentation and a reference for other imaging scenarios.
By Sarmad Khan, Basim Azam, Arslan Shaukat