arXiv Computer Vision By Shuangping Huang, Hao Liang, Qingfeng Wang, Chulong Zhong, Zijian Zhou, Miaojing Shi

SEG-SAM: Semantic-Guided SAM for Unified Medical Image Segmentation

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SEG-SAM is a unified medical image segmentation model that builds on the Segment Anything Model (SAM) by integrating semantic medical knowledge. It introduces a semantic‑aware decoder separate from SAM’s original decoder to handle both semantic segmentation of prompted objects and classification of unprompted objects. The model also incorporates key medical category characteristics from large language models via a text‑to‑vision semantic module and uses a cross‑mask spatial alignment strategy to improve overlap between predictions, achieving superior performance over existing SAM‑based and task‑specific methods.

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