The paper introduces MedREAL, a unified framework that aligns linguistic reasoning with spatial grounding for medical visual question answering and segmentation. MedREAL employs Seg Anchored Reasoning Pooling (SARP) to extract semantic evidence from segmentation tokens and a Reasoning-to-Visual (R2V) fusion mechanism to integrate these features into a segmentation pipeline. Using the newly created MedRAVS-13K dataset, MedREAL achieves superior performance, reporting 68.49% gIoU and 70.47% cIoU, and generates evidence masks that consistently match textual diagnoses.
By Haowen Gu, Gensheng Pei, Junzhu Mao, Qiong Wang, Mingwu Ren, Yazhou Yao
arXiv:2608. 09818v1 Announce Type: cross Abstract: Reliable medical image understanding requires models to connect clinical language and visual reasoning with pixel-level grounding.
By Haoyu Yang, Meixing Shi, Zengjie Chen, Haoran Sun, Haitao Leng, Xiaoming Shi, Yuxiang Cai, Yankai Jiang
arXiv:2608. 10635v1 Announce Type: cross Abstract: Medical Vision-Language Models (Med-VLMs) excel at verbalizing visual content, yet precise visual perception, segmentation, and grounding remain challenging.
By Yuan Wang, Hualiang Wang, Yixin Chen, Songtao Jiang, Shujian Gao, Jiaming Lin, Siming Fu, Jian Wu, Zuozhu Liu
arXiv:2607. 04344v1 Announce Type: cross Abstract: While Large Vision-Language Models (VLMs) demonstrate remarkable generic capabilities, their clinical reasoning in specialized domains like ocular surface diseases (OSDs) is severely hindered by a paucity of high-fidelity, multimodal instruction-tuning data.
By Hao Wei, Wenjin Qi, Dasen Dai, Minqing Zhang, Wu Yuan
SEG-SAM is a unified medical image segmentation model that builds on the Segment Anything Model (SAM) by integrating semantic medical knowledge. It introduces a semantic‑aware decoder separate from SAM’s original decoder to handle both semantic segmentation of prompted objects and classification of unprompted objects. The model also incorporates key medical category characteristics from large language models via a text‑to‑vision semantic module and uses a cross‑mask spatial alignment strategy to improve overlap between predictions, achieving superior performance over existing SAM‑based and task‑specific methods.
By Shuangping Huang, Hao Liang, Qingfeng Wang, Chulong Zhong, Zijian Zhou, Miaojing Shi
arXiv:2509.22404v2 Announce Type: replace
Abstract: Anatomical understanding, which is the ability to identify, localize, or segment anatomical structures, is critical in medical image analysis; howe...
By Yiwei Li, Yikang Liu, Jiaqi Guo, Lin Zhao, Zheyuan Zhang, Xiao Chen, Boris Mailhe, Ankush Mukherjee, Terrence Chen, Shanhui Sun
arXiv:2505.03380v2 Announce Type: replace
Abstract: Accurate delineation of tumors and surrounding organs-at-risk is essential for radiotherapy, surgery and treatment response assessment, yet remains...
By Haonan Wang, Jiaji Mao, Lehan Wang, Qixiang Zhang, Marawan Elbatel, Yi Qin, Huijun Hu, Baoxun Li, Wenhui Deng, Weifeng Qin, Hongrui Li, Jialin Liang, Jun Shen, Xiaomeng Li
arXiv:2607.12896v3 Announce Type: replace
Abstract: Medical image segmentation foundation models are expected to generalize across diverse clinical scenarios, yet existing universal methods remain fr...
By Yunzhou Li, Jiesi Hu, Yanwu Yang, Hanyang Peng, Chenfei Ye, Jianfeng Cao, Yixuan Yuan, Ting Ma
arXiv:2511. 12110v5 Announce Type: replace-cross Abstract: Despite notable progress in text-guided medical image segmentation nowadays, these methods are limited to single-round dialogues and fail to support multi-round reasoning, which is important for medical education scenarios.
By Qinyue Tong, Ziqian Lu, Jun Liu, Rui Zuo, Zheming Lu, Yueming Jin
arXiv:2606. 17958v1 Announce Type: cross Abstract: Semi-supervised medical image segmentation has emerged as a dominant research problem in medical image analysis, mitigating annotation scarcity by leveraging consistency regularization on unlabeled data.
By Yuming Chen, Yuxin Xie, Tao Zhou, Yi Zhou
The paper introduces LIRSeg, a method that replaces explicit Chain-of-Thought reasoning in multimodal large language models with a compact set of learnable latent tokens for reasoning segmentation. LIRSeg is trained in two stages—spatial alignment and GRPO—while employing extreme-advantage sampling, decoupled exploration-stability updates, and latent diversity amplification to enhance token informativeness. Experiments show that LIRSeg improves segmentation accuracy and reasoning efficiency, achieving significant gIoU gains over the VisionReasoner baseline and reducing reasoning tokens by about 16×.
By Tianhang Guo, Yulin He, Wei Chen, Wenjuan Zhou, Yuhang Li, Xinbiao Gan
arXiv:2607. 23794v1 Announce Type: cross Abstract: Pathological diagnosis is inherently multi-scale, requiring the integration of global tissue architecture at low magnification with cellular morphology at higher magnification.
By Chi Phan, Tianyi Zhang, Yufeng Wu, Qiaochu Xue, Jiajie Zhang, Linghan Cai, Zeyu Liu, Sudong Wang, Yueming Jin, Dan Hu