arXiv Computer Vision

SEG-SAM: Semantic-Guided SAM for Unified Medical Image Segmentation

SEG-SAM is a unified medical image segmentation model that builds on the Segment Anything Model (SAM) by integrating semantic medical knowledge. It introduces a semantic‑aware decoder separate from SAM’s original decoder to handle both semantic segmentation of prompted objects and classification of unprompted objects. The model also incorporates key medical category characteristics from large language models via a text‑to‑vision semantic module and uses a cross‑mask spatial alignment strategy to improve overlap between predictions, achieving superior performance over existing SAM‑based and task‑specific methods.

arXiv Computer Vision
Sep 10

Synergistic Vision-Language Reinforcement Enables Scalable On-Demand Analysis across Diverse Clinical Tasks

arXiv:2505.03380v2 Announce Type: replace Abstract: Accurate delineation of tumors and surrounding organs-at-risk is essential for radiotherapy, surgery and treatment response assessment, yet remains...

By Haonan Wang, Jiaji Mao, Lehan Wang, Qixiang Zhang, Marawan Elbatel, Yi Qin, Huijun Hu, Baoxun Li, Wenhui Deng, Weifeng Qin, Hongrui Li, Jialin Liang, Jun Shen, Xiaomeng Li
arXiv Computer Vision
Aug 25

Localization-Infused Vision-Language Semantic Fusion for Text-Guided Medical Image Segmentation

The paper introduces LoG, a localization‑infused vision‑language fusion framework for text‑guided medical image segmentation. LoG jointly performs multi‑scale target localization to explicitly capture target‑oriented semantics and employs three levels of localization‑infused fusion—feature, attention, and loss—to integrate spatial information into segmentation. Experiments on three benchmark datasets across three imaging modalities show that LoG consistently outperforms state‑of‑the‑art methods.

By Songyue Han, Mingye Zou, Shuchang Ye, Lei Bi, Mingyuan Meng
arXiv Machine Learning
Aug 18

Comprehensive language-image pre-training for 3D medical image understanding

arXiv:2510. 15042v3 Announce Type: replace-cross Abstract: In the 3D medical image domain, vision-language pre-training is used to create vision-language encoders (VLEs) that can support radiologists by retrieving patients with similar abnormalities, predicting likelihoods of abnormality, or, with downstream adaptation, generating radiological reports.

By Tassilo Wald, Ibrahim Ethem Hamamci, Yuan Gao, Sam Bond-Taylor, Harshita Sharma, Maximilian Ilse, Cynthia Lo, Olesya Melnichenko, Anton Schwaighofer, Noel C. F. Codella, Maria Teodora Wetscherek, Klaus H. Maier-Hein, Panagiotis Korfiatis, Valentina Salvatelli, Javier Alvarez-Valle, Fernando P\'erez-Garc\'ia
arXiv AI
Aug 28

From Reasoning to Pixels: Grounded Medical Multimodal LLMs for VQA and Segmentation

The paper introduces MedREAL, a unified framework that aligns linguistic reasoning with spatial grounding for medical visual question answering and segmentation. MedREAL employs Seg Anchored Reasoning Pooling (SARP) to extract semantic evidence from segmentation tokens and a Reasoning-to-Visual (R2V) fusion mechanism to integrate these features into a segmentation pipeline. Using the newly created MedRAVS-13K dataset, MedREAL achieves superior performance, reporting 68.49% gIoU and 70.47% cIoU, and generates evidence masks that consistently match textual diagnoses.

By Haowen Gu, Gensheng Pei, Junzhu Mao, Qiong Wang, Mingwu Ren, Yazhou Yao
arXiv AI
Sep 15

MedSAM3: Delving into Segment Anything with Medical Concepts

MedSAM-3 is a text‑promptable medical segmentation model that builds on the Segment Anything Model (SAM) by fine‑tuning it with medical images and semantic concept labels. It enables precise anatomical segmentation through open‑vocabulary text descriptions, moving beyond purely geometric prompts. The accompanying MedSAM-3 Agent incorporates multimodal large language models to perform complex reasoning and iterative refinement, and experiments across X‑ray, MRI, ultrasound, CT, and video modalities show it outperforms existing specialist and foundation models.

By Anglin Liu, Xu R. Cao, Yifan Shen, Yi Lu, Xiang Li, Qianqian Chen, Jintai Chen