The paper introduces FreNet, a feature reconfiguration framework that incorporates visual priors for medical lesion segmentation. FreNet performs pixel‑level reconfiguration before encoding using an Implicit Prior Neural Network (IPNN) that leverages SAM, and feature‑level reconfiguration during encoding via a Dual‑domain Feature Reconfiguration (DFR) module, which includes a Frequency Decoupling Module (FDM) and a Spatial Localization Module (SLM). Experiments on nine benchmarks across three imaging modalities show that FreNet outperforms state‑of‑the‑art methods, achieving a 5.0% Dice improvement over the best baseline on the ETIS dataset and a 7.2% improvement over SAM.
By Yinan Liu, Jiankang Hong, Zhen Gao, Ye Lu
The paper introduces Spatial‑FAD, a few‑shot medical anomaly detection framework that fuses Vision‑Language Model (CLIP) semantics with spatial priors from Vision Foundation Models (DINO). A VFM‑enhanced adapter injects structural affinity into CLIP features, while a sliding‑window aggregation produces high‑resolution embeddings for finer lesion localization. Prototype‑enhanced support memory further improves efficiency and performance, yielding significant gains on Liver CT, Retinal OCT, and Brain MRI datasets, notably an 11.4% Dice improvement in 4‑shot scenarios.
By Juzheng Miao, Yuchen Yuan, Cheng Chen, Pheng-Ann Heng
InstEditSeg is a generative framework that treats medical segmentation as an instruction-driven image editing task. Instead of producing binary masks, it renders a color-coded overlay on the original image guided by textual instructions, leveraging latent diffusion models to align with natural image distributions and reduce domain gaps. The method incorporates a DINOv3 visual encoder and a multi-scale feature pyramid fused into the diffusion U‑Net, and uses a dual‑branch classifier‑free guidance strategy to lower inference cost, achieving competitive accuracy on polyp and skin lesion datasets while improving cross‑domain generalization and multi‑lesion segmentation.
By Ziquan Liu, Zhewei Zhu, Xuyang Shi
Accurate medical image interpolation and anatomical structure segmentation are fundamental for computer-aided diagnosis and treatment planning. Anisotropic medical volumes with sparse through-plane sampling often suffer from structural discontinuity and boundary blur, hindering reliable clinical image analysis.
Medical image segmentation relies on the ability of encoder-decoder architectures to translate rich feature representations into accurate pixel-level predictions under challenging conditions such as low contrast, structural ambiguity, and scale variability. While recent advances in large-scale pretraining and transformer-based encoders have substantially improved feature extraction, segmentation accuracy remains constrained by decoder design, particularly in terms of cross-scale alignment, contextual integration, and boundary preservation.
arXiv:2608. 20229v1 Announce Type: cross Abstract: Anatomically plausible segmentation remains challenging because of low contrast, ambiguous boundaries, and modality-specific artifacts.
By Mosharof Hossain, Md Rabiul Islam, Limon Halder, Erchin Serpedin, Md Kamrul Hasan