arXiv AI

Learning a patient world model for health system simulation in intensive care

arXiv AI
Oct 28

Learning response-aware patient dynamics for respiratory support

The paper introduces a response‑aware patient dynamics model that explicitly captures how respiratory support alters a patient’s short‑term physiological trajectory. By decomposing predicted physiological change into baseline dynamics and support‑associated deviations anchored to room‑air reference, the model updates latent patient states across a forecast horizon. Experiments on ICU cohorts from two institutions show that the model matches baseline trajectory predictions overall and consistently improves performance when physiological states are changing.

By Xiaolei Lu, Shamim Nemati
arXiv Machine Learning
Jun 4

VentAgent: When LLMs Learn to Breathe -- Multi-Objective Arbitration for ARDS Ventilation

arXiv:2606. 04632v1 Announce Type: new Abstract: Mechanical ventilation for Acute Respiratory Distress Syndrome (ARDS) requires balancing competing physiological goals, including oxygenation, lung protection, and acid-base homeostasis.

By Teqi Hao, Yuxuan Fu, Xiaoyu Tan, Shaojie Shi, Bohao Lv, Yinghui Xu, Xihe Qiu
Hugging Face Trending Papers
Sep 8

NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

NOAH is a generative transformer that models the entire multimodal patient journey by integrating bidirectional time and a variational latent space to capture continuous, stochastic clinical trajectories. Trained on over 559 million events from 431,000 hospital visits, it processes medical images, time‑series, numeric signals, categorical events, and both structured and unstructured records. The model supports autoregressive forecasting, zero‑shot classification, and counterfactual simulations, yielding strong predictive performance across 15 ICD chapters, 29 comorbidities, and time‑to‑event outcomes.

arXiv Machine Learning
Aug 4

Inferring Relative Consequences of Mechanical Ventilation from Observational Data Using Game-Based Comparisons

arXiv:2510. 15127v3 Announce Type: replace-cross Abstract: Identifying the effects of mechanical ventilation (MV) protocols in critical care requires analyzing data from heterogeneous patient-ventilator systems in the clinical decision-making environment.

By David J. Albers, Tell D. Bennett, Jana de Wiljes, George Hripcsak, Bradford J. Smith, Peter D. Sottile, J. N. Stroh
arXiv AI
Sep 10

NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

NOAH is a generative transformer that learns the full multimodal patient journey by integrating bidirectional time and a variational latent space. Trained on over 559 million clinical events from 431,000 hospital visits, it processes medical images, time‑series, numeric signals, categorical events, and both structured and unstructured records. The model supports autoregressive forecasting, zero‑shot classification, and counterfactual intervention simulation, yielding strong performance on clinical outcomes, ICD chapters, comorbidities, and time‑to‑event prediction.

By Tobias Susetzky, Raphael Rehms, Dmitrii Seletkov, \"Ozg\"un Turgut, Michelle Espranita Liman, Lisa Steinhelfer, Rickmer Braren, Daniel Rueckert
arXiv AI
Sep 30

Physics-Informed Multi-Agent Coordination for Hospital Patient Flow Optimization

The paper introduces a Physics‑Informed Multi‑Agent Coordination framework that embeds calibrated BCMP queueing topologies into a decentralized multi‑agent reinforcement learning system for hospital patient flow. It formulates the problem as a Decentralized Partially Observable Markov Decision Process with coupled resource constraints, enabling departmental agents to negotiate patient routing and service scaling while exchanging localized action fingerprints to handle non‑stationarity. Empirical tests on MIMIC‑IV data show the approach reduces cumulative system delay compared to static Markovian models, heuristic dispatching, and independent multi‑agent baselines, all while preserving clinical safety constraints.

By Guoqing Zhang, Rafik Hadfi, Takayuki Ito