arXiv:2605. 28910v2 Announce Type: replace-cross Abstract: Large language models (LLMs) have shown promise on summarization tasks, but they often produce hallucinations, which are unsupported or incorrect statements that limit their reliability in specialized healthcare applications.
By Shamanth Kuthpadi Seethakantha, Dung Ngoc Thai, Vara Prasad Gudi, Simran Tiwari, Rami Matar, Avijit Mitra, Wenlong Zhao, Andrew McCallum, Wael Salloum
arXiv:2607. 15380v1 Announce Type: cross Abstract: Electronic health records combine free-text clinical narratives with structured measurements such as vital signs, laboratory values, and comorbidities.
By Ajay Madhavan Ravichandran, Bilgin Osmandoja, Klemens Budde, Klaus Netter, Tobias Strapatsas, Aljoscha Burchardt, Sebastian M\"oller, Roland Roller
arXiv:2607. 20453v1 Announce Type: cross Abstract: Large language models show promise for clinical prediction, but zero-shot performance on specialized tasks is limited by incomplete domain knowledge, especially for smaller locally deployable models.
By Jessica Sena, Shesadree Priyadarshani, Miguel Contreras, Bharat Gandhi, Scott Siegel, Subhash Nerella, Parisa Rashidi
arXiv:2605. 01189v2 Announce Type: replace Abstract: Clinical AI adoption is hindered by the black-box/grey-box nature of high-performing models, which lack the ontological grounding and narrative transparency required for professional-level explainability.
By Anuradha Chandrasekaran, Dimitrios Zikos, Mutlu Mete, Alan Pang, Brady D. Lund, Kewei Sha
arXiv:2607. 14116v1 Announce Type: cross Abstract: Free-form radiology reports contain rich clinical descriptions, yet converting them for reliable segmentation remains challenging due to the inherent variability of natural language.
By Anghong Du, Theodoros N. Arvanitis, Colin Watts, Alejandro F. Frangi, Le Zhang
arXiv:2606. 02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs).
By Bo-Hong Wang, Baicheng Peng, Ruilin Wang, Jun Bai, Ziyang Song, Yue Li
arXiv:2607. 20462v1 Announce Type: new Abstract: Large language models (LLMs) are increasingly integrated into clinical workflows, stressing the need for reliable traceability of model-generated output with watermarking.
By Melanie Rieff, Robin Staab, Thibaud Gloaguen, Stefan Hegselmann, Martin Vechev
arXiv:2601. 06300v2 Announce Type: replace-cross Abstract: Clinical trial amendments frequently introduce delays, increased costs, and administrative burden, with eligibility criteria being the most commonly amended component.
By Trisha Das, Mandis Beigi, Jacob Aptekar, Jimeng Sun
arXiv:2608. 05375v1 Announce Type: new Abstract: Clinical machine learning (ML) has the potential to support high-stakes medical decision-making, but reliable deployment is often constrained by scarce, heterogeneous, and temporal complexity.
By Ruilin Wang, Bo-Hong Wang, Elizabeth Kourbatski, Jun Bai, Hegang Chen, Ziyang Song, Gilles Boire, Marie Hudson, Yue Li
arXiv:2605. 30295v2 Announce Type: replace-cross Abstract: Large language models (LLMs) show promise for clinical reasoning and decision support, but evaluation in realistic, electronic health record-congruent settings remains limited.
By Valentina Bui Muti, Eug\'enie Dulout, Ziquan Fu
arXiv:2607. 00147v1 Announce Type: new Abstract: Rare disease differential diagnosis is a critical yet arduous clinical task, requiring physicians to identify precise phenotypes from complex, unstructured patient symptoms and execute intricate reasoning within a vast search space.
By Deyang Jiang, Haoran Wu, Ziyi Wang, Yiming Rong, Yunlong Zhao, Ye Jin, Bo Xu
arXiv:2603. 22213v2 Announce Type: replace-cross Abstract: While large language models (LLMs) are pretrained on massive amounts of data, their knowledge coverage remains incomplete in specialized, data-scarce domains, motivating extensive efforts to study synthetic data generation for knowledge injection.
By Kexian Tang, Jiani Wang, Shaowen Wang, Kaifeng Lyu