Future Querying: Can LLMs Serve as Implicit Medical World Models?
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arXiv:2606. 26879v1 Announce Type: new Abstract: Synthetic data is increasingly used to enable the development and evaluation of AI systems in domains where access to real-world data is restricted.
arXiv:2610.08093v1 Announce Type: cross Abstract: Developing reliable models for clinical tasks, such as Medical Question Answering (QA), is severely constrained by the limited availability of high-q...
Synthetic data is increasingly used to enable the development and evaluation of AI systems in domains where access to real-world data is restricted. In healthcare, clinical documentation presents particular challenges due to its sensitivity.
The paper introduces BRIE, a scalable framework that automatically creates question–answer pairs from longitudinal electronic health record notes, validated by nineteen clinicians. It offers a continuously maintainable benchmark for evaluating large language models in clinical settings, addressing limitations of manual, costly, and quickly outdated existing benchmarks. Experiments across nine LLMs and five inference strategies reveal that even state‑of‑the‑art systems often miss clinically important information, especially for synthesis‑heavy queries.
The paper introduces BRIE, a continuously maintainable benchmark for evaluating large language models (LLMs) in electronic health record (EHR) information retrieval. It presents a scalable framework that automatically generates question–answer pairs from longitudinal EHR notes, validated by nineteen clinicians. The benchmark allows assessment of multiple inference strategies and highlights that state‑of‑the‑art LLMs often miss clinically important information, especially when synthesis across documents is required.
The paper introduces a clinically grounded privacy evaluation framework for medical language models, assessing leakage across a spectrum of adversarial access levels—from publicly inferable demographics to leaked note fragments. Using this framework on an LM pretrained on 378,000 clinical notes, the authors find that routine encounter metadata leads to high verbatim memorization and significant recovery of sensitive diagnoses (e.g., AUROC 0.91 for abortion, 0.82 for HIV). They also note that exact-match memorization can overstate disclosure, with 36% of memorized tokens being templated documentation, underscoring the risks of training on longitudinal clinical data and offering a reusable evaluation tool.