arXiv Computation and Language

Knowledge Graph-Augmented Ambient AI for Clinical Note Generation

arXiv AI
Oct 7

Symphony for Text Generation: Benchmarking Clinical Note Generation

arXiv:2610.08161v1 Announce Type: cross Abstract: Ambient documentation systems are rapidly gaining adoption, yet their impact on clinical note quality remains poorly characterized. We introduce MedC...

By Daniel Varab, Victor Petr\'en Bach Hansen, Asbj{\o}rn W. Helge, Kevin Pelgrims, Mathias Baltzersen, Adrian Young-San Roessler, Vanessa Klungtvedt, Maximilian Brand, Lasse Krogsb{\o}ll, Henrik Cullen, Lars Maal{\o}e
arXiv AI
Jul 22

Trajectory-Aware Clinical Risk Prediction via Severity-Grounded Knowledge Graphs and Retrieval-Augmented Generation

arXiv:2607. 18270v1 Announce Type: new Abstract: While Electronic Health Records (EHRs) offer a wealth of clinical data, effectively augmenting a patient's records with heterogeneous external knowledge to predict the patient's clinical risk remains a significant challenge.

By Kyunghoon Jeon, Youmin Ko, Woohwan Jung, Hyunjoon Kim
arXiv AI
Jul 13

Evaluating Retrieval-Augmented Generation vs. Long-Context Input for Clinical Reasoning over EHRs

arXiv:2508. 14817v2 Announce Type: replace-cross Abstract: Objective: To evaluate whether retrieval-augmented generation (RAG) can serve as an efficient alternative to long-context prompting for clinical reasoning over electronic health records (EHRs).

By Skatje Myers, Dmitriy Dligach, Timothy A. Miller, Samantha Barr, James Landefeld, Yanjun Gao, Matthew Churpek, Anoop Mayampurath, Majid Afshar
arXiv AI
Aug 25

Clinical Graph-JEPA: Predictive Patient-State Knowledge Graphs for Cognitive Decision Support

The paper introduces Clinical Graph-JEPA, a framework for building and refining predictive patient-state knowledge graphs from clinical records. It combines multi-agent relation proposal, ontology-aware normalization, deterministic evidence scoring, and JEPA-based latent refinement to construct evidence-scored graphs from MIMIC-IV data and recover missing clinical relations. Experiments show that injecting discharge-note representations into note-grounded entities boosts leave-one-out MRR by 31% relative improvement.

By Kushagra Yadav, Nalin Prabhath, Amit Lamba, Goeun Han, Yining Mao
arXiv AI
Jun 16

MedSynth: Realistic, Synthetic Medical Dialogue-Note Pairs

arXiv:2508. 01401v2 Announce Type: replace-cross Abstract: Physicians spend significant time documenting clinical encounters, a burden that contributes to professional burnout.

By Ahmad Rezaie Mianroodi, Amirali Rezaie, Niko Grisel Todorov, Nadine A. Friedrich, Maria P Mogollon, Alexander Hernandez-Tirado, Guillermo Lopez Garcia, Cyril Rakovski, Frank Rudzicz
Hugging Face Trending Papers
Sep 24

A Living Benchmark for Information Retrieval from Electronic Health Records

The paper introduces BRIE, a scalable framework that automatically creates question–answer pairs from longitudinal electronic health record notes, validated by nineteen clinicians. It offers a continuously maintainable benchmark for evaluating large language models in clinical settings, addressing limitations of manual, costly, and quickly outdated existing benchmarks. Experiments across nine LLMs and five inference strategies reveal that even state‑of‑the‑art systems often miss clinically important information, especially for synthesis‑heavy queries.

arXiv Machine Learning
Sep 21

HERMES: Contrast-Aware Knowledge Graph Reasoning from Clinical Notes for Patient Outcome Prediction

HERMES is a graph-based framework that uses only clinical text to predict patient outcomes. It builds personalized Knowledge Graphs from clinical notes via Large‑Language‑Model‑guided extraction and Contrastive Logic Modeling, capturing temporal dynamics and treatment changes. A Graph Attention Network then synthesizes patient representations, and experiments on MIMIC‑III and MIMIC‑IV show HERMES outperforms text‑only baselines for in‑hospital mortality and 30‑day readmission prediction.

By Gia-Bach Nguyen, Hoang-Ha Nguyen, Tuan-Cuong Vuong, Trang Mai Xuan, Duy Quoc Ngo, Tien-Cuong Nguyen, Huan Vu, Thien Van Luong
arXiv AI
Oct 2

Clinical Note Bloat Reduction for Efficient LLM Use

The paper introduces TRACE, a method that removes duplicated text—known as note bloat—from clinical notes by leveraging EHR metadata and frequency-based de‑duplication. Across 5.3 million notes from diverse patient cohorts, TRACE eliminated 47.3 % of chart text while preserving information extraction and prediction performance, with only 0.3–6.6 % of removed content being author‑generated. The authors project that applying TRACE could yield net savings of $1.00 M to $13.58 M over three years at a large academic center, depending on model pricing schemes.

By Jordan L. Cahoon, Chloe Stanwyck, Asad Aali, Rachel Madding, Sulaiman S. Somani, Emma Sun, Yixing Jiang, Renumathy Dhanasekaran, Emily Alsentzer