arXiv:2608.23248v1 Announce Type: cross
Abstract: Traditional clinical prediction models rely on task-specific pipelines and curated, structured data, which scale poorly and underutilize unstructured...
By Siri Willems, James Butterworth, Lore Goetschalckx, Peter Vrancx, Philippe Modard, Elke Giets, Ludovic Denoyer
The paper introduces BRIE, a scalable framework that automatically creates question–answer pairs from longitudinal electronic health record notes, validated by nineteen clinicians. It offers a continuously maintainable benchmark for evaluating large language models in clinical settings, addressing limitations of manual, costly, and quickly outdated existing benchmarks. Experiments across nine LLMs and five inference strategies reveal that even state‑of‑the‑art systems often miss clinically important information, especially for synthesis‑heavy queries.
The paper introduces BRIE, a continuously maintainable benchmark for evaluating large language models (LLMs) in electronic health record (EHR) information retrieval. It presents a scalable framework that automatically generates question–answer pairs from longitudinal EHR notes, validated by nineteen clinicians. The benchmark allows assessment of multiple inference strategies and highlights that state‑of‑the‑art LLMs often miss clinically important information, especially when synthesis across documents is required.
By Jordan L. Cahoon, Chloe O. Stanwyck, Sulaiman Somani, Philip Chung, Kevin R Keet, Kameron C. Black, Andrea T. Fisher, Sarita Khemani, Jerry Liu, Stephen Ma, Saloni K. Maharaj, Rita M. Pandya, Eduardo Perez-Guerrero, Priyanka Pillai, Lisa Shieh, David J. H. Wu, James Xie, James C. McAvoy, Teresa Nguyen, Jessica Tran, Lucy Yin, Bridget Lin, Alison Callahan, Jason A. Fries, Nigam H. Shah, Emily Alsentzer
arXiv:2607. 12310v1 Announce Type: cross Abstract: While modern question answering (QA) systems excel on clean, schema-aligned corpora, real-world knowledge is rarely so neatly packaged.
By Michael Solodko, Steven Gong, Guangwei Yu, Satya Krishna Gorti, Jesse C. Cresswell, Victor Zhong
arXiv:2610.08327v1 Announce Type: new
Abstract: Large language models (LLMs) have shown promise in medical question answering and clinical reasoning, yet their improvement remains constrained by stat...
By Xilin Dang, Weilin Ruan, Xue Yang, Jinghao Wang, Xiaowei Hu, Jinpeng Li, Pheng-Ann Heng
arXiv:2605. 30295v2 Announce Type: replace-cross Abstract: Large language models (LLMs) show promise for clinical reasoning and decision support, but evaluation in realistic, electronic health record-congruent settings remains limited.
By Valentina Bui Muti, Eug\'enie Dulout, Ziquan Fu
The paper introduces a method for generating multilingual reasoning traces for medical question answering using large language models. It creates 500,000 reasoning traces in English, Italian, and Spanish by retrieving medical information from Wikipedia and applies them to MedQA and MedMCQA datasets extended into Italian and Spanish. The approach improves performance in both few‑shot in‑context learning and supervised fine‑tuning, achieving state‑of‑the‑art results for 8B‑parameter LLMs and releasing all resources for further research.
By Pietro Ferrazzi, Aitor Soroa, Rodrigo Agerri
arXiv:2603.00842v2 Announce Type: replace
Abstract: Biomedical multimodal assistants have the potential to unify radiology, pathology, and clinical-text reasoning, yet a critical deployment gap remai...
By Kai Zhang, Zhengqing Yuan, Cheng Peng, Songlin Zhao, Mengxian Lyu, Ziyi Chen, Yanfang Ye, Wei Liu, Ying Zhang, Kaleb E Smith, Lifang He, Lichao Sun, Yonghui Wu
arXiv:2601. 05451v2 Announce Type: replace Abstract: Recent advances in text-to-SQL have been driven by larger models, better datasets, and new training methods like RLVR.
By Marko Sterbentz, Kevin Cushing, Cameron Barrie, Kristian J. Hammond
Synthetic data is increasingly used to enable the development and evaluation of AI systems in domains where access to real-world data is restricted. In healthcare, clinical documentation presents particular challenges due to its sensitivity.
arXiv:2607. 06452v1 Announce Type: cross Abstract: Biomedical question answering requires not only accurate extraction of information from scientific literature but also reliable integration of evidence across multiple documents.
By Taeyun Roh, Eunha Lee, Wonjune Jang, Sohyun Chung, Junha Jung, Jaewoo Kang
arXiv:2608. 05375v1 Announce Type: new Abstract: Clinical machine learning (ML) has the potential to support high-stakes medical decision-making, but reliable deployment is often constrained by scarce, heterogeneous, and temporal complexity.
By Ruilin Wang, Bo-Hong Wang, Elizabeth Kourbatski, Jun Bai, Hegang Chen, Ziyang Song, Gilles Boire, Marie Hudson, Yue Li