arXiv AI

A Knowledge-Injection Framework for Zero-Shot Adaptation of LLMs to Delirium Prediction

arXiv:2607. 20453v1 Announce Type: cross Abstract: Large language models show promise for clinical prediction, but zero-shot performance on specialized tasks is limited by incomplete domain knowledge, especially for smaller locally deployable models.

arXiv AI

Jul 21

Retrieval-Augmented Interpretable Learning: Towards Task-Specific Zero-Shot Models in Healthcare

arXiv:2607. 17508v1 Announce Type: cross Abstract: We introduce Retrieval-Augmented Interpretable Learning (RAIL), a probabilistic meta-learning framework for zero-shot generation of task-specific interpretable models that synthesizes coefficient-space structure from natural-language task descriptions and a memory of previously learned task-specific predictors.

By Sazan Mahbub, Caleb Ellington, Zhiyuan Li, Yixin Yang, Souvik Kundu, Ben Lengerich, Eric P. Xing

rag safety

arXiv AI

Aug 3

EarlyDx: An Admission-Anchored Benchmark for Open-Ended Generation of Evidence-Supported ED-Encounter Diagnoses

arXiv:2607. 28788v1 Announce Type: new Abstract: Clinical diagnosis at hospital admission must be made rapidly from limited, incomplete evidence.

By Jiahui Li, Ruili Fang, Zishuai Liu, Yutong Guo, Nan Yang, Wenzhan Song, Jin Lu, Fei Dou

llms benchmarks

arXiv Machine Learning

Jul 9

Counterfactual Modeling with Fine-Tuned LLMs for Health Intervention Design and Sensor Data Augmentation

arXiv:2601. 14590v3 Announce Type: replace Abstract: Counterfactual explanations (CFEs) provide human-centric interpretability by identifying the minimal, actionable changes required to alter a machine learning model's prediction.

By Shovito Barua Soumma, Asiful Arefeen, Stephanie M. Carpenter, Melanie Hingle, Hassan Ghasemzadeh

llms fine-tuning multimodal safety

arXiv Computation and Language

3d ago

MedKIT: Evaluating Knowledge Integration and Generalization in Large Language Models

arXiv:2609.38543v1 Announce Type: new Abstract: Constantly evolving real-world knowledge necessitates models to be updated continuously. Especially in medicine, as clinical evidence changes over time...

By Lukas Thede, Yash Kumar Atri, David Chen, Danielle Bitterman, Matthias Bethge, Tom Hartvigsen, Zeynep Akata

llms benchmarks safety

arXiv Machine Learning

2d ago

Learning to Select Source-Traceable Evidence for Language-Model Prediction from Irregular Clinical Time Series

arXiv:2605.20292v2 Announce Type: replace Abstract: Numerical time-series models effectively process irregular electronic health record (EHR) trajectories, but do not expose which temporal patterns s...

By Kwanhyung Lee, Juhwan Choi, Jongheon Kim, Joohyung Lee, Hyeongwon Jang, Jeonguk Lee, Jisoo Jung, Eunho Yang

llms benchmarks

arXiv AI

Jun 8

REMEDI: A Benchmark for Retention and Unlearning Evaluation in Multi-label Clinical Disease Inference

arXiv:2606. 07141v1 Announce Type: cross Abstract: Language models trained for clinical disease inference are trained on patient data, which may include sensitive and private information, and data owners may request the removal of their data from a trained model due to privacy or copyright concerns.

By Anurag Sharma, Sai Teja Chunchu, Prasenjit Mitra, Sandipan Sikdar, Koustav Rudra

llms benchmarks safety

arXiv Machine Learning

Sep 22

Didactic knowledge or Clinical Cases? How Data Types Shape Medical Large Language Models

arXiv:2609.22161v1 Announce Type: cross Abstract: Medical large language models are commonly trained on mixtures of didactic data (e.g., textbooks) and clinical data (e.g., patient records), yet how...

By Yuzheng Fan, Haochun Wang, Sendong Zhao, Xiao Han, Ming Ma, Bing Qin

llms

arXiv AI

Jun 30

Primary ICD Category Prediction using LLM-based Probing

arXiv:2606. 28798v1 Announce Type: new Abstract: Objective: ICD codes are central to reimbursement, research, and population health surveillance, yet automated coding systems often struggle to integrate diagnostic signals from both clinical narratives and structured electronic health record (EHR) variables.

By Chengyuan Liu, Xinyue Zhang, Yao Li, Guanting Chen

llms rag multimodal

arXiv Machine Learning

Aug 14

CoMedBench: A Multi-Source Benchmark of Synthetic Medical Data Fidelity and Downstream Utility

arXiv:2608. 12805v1 Announce Type: new Abstract: Access to clinical data is essential for developing reliable healthcare machine learning systems, but direct use of electronic health records is constrained by privacy regulation, institutional review, data-use agreements, and the risk of re-identification.

By Akanta Das, Al Amin Farhad, Mrinmoy Sarkar Anto, David Rehkopf, Ayin Vala, Tanmoy Sarkar Pias

benchmarks safety

arXiv Computation and Language

Sep 22

Knowledge-Graph Grounding Helps LLMs Only for Out-of-Training Knowledge: A Controlled Study on Clinical Question Answering

arXiv:2606.22419v3 Announce Type: replace Abstract: A recent Nature Medicine study reports that general-purpose frontier LLMs outperform specialized retrieval-augmented clinical tools on medical benc...

By Madhulatha Mandarapu, Sandeep Kunkunuru

llms rag agents nlp benchmarks

arXiv Machine Learning

Jun 18

Zero-Shot Active Feature Acquisition via LLM-Elicitation

arXiv:2606. 18933v1 Announce Type: new Abstract: Active feature acquisition (AFA) sequentially selects which features to observe to reach a classification or ranking decision.

By Binyamin Perets, Natalie Mendelson, Shiran Vainberg, Yehuda Chowers, Shai Shen-Orr, Shie Mannor

llms

arXiv Machine Learning

Jun 24

PORTER: Language-Grounded Event Representations for Portable Structured EHR Foundation Models

arXiv:2606. 24102v1 Announce Type: cross Abstract: Most electronic health record (EHR) foundation models encode clinical events as discrete event tokens from a fixed vocabulary and therefore cannot directly represent events containing unseen concepts or new combinations of concepts and attributes such as numeric values.

By Lin Lawrence Guo, Adam Paul Yan, Emily Vettese, Lillian Sung

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