arXiv:2607. 07761v1 Announce Type: new Abstract: Large language models (LLMs) have emerged as important tools in healthcare, showing growing potential for clinical reasoning and patient care.
By Qi Peng, Jiatong Li, Sirui Huang, Yiyang Jiang, Kaisong Gong, Ronger Ding, Shijie Ye, Changmeng Zheng, Yi Cai, Xiaobo Yang, Jin Huang, Xiao-Yong Wei, Qing Li
arXiv:2512. 01241v3 Announce Type: replace-cross Abstract: Large language models (LLMs) are routinely used by physicians and patients for medical advice, yet their clinical safety profiles remain poorly characterized.
By David Wu, Fateme Nateghi Haredasht, Saloni Kumar Maharaj, Priyank Jain, Jessica Tran, Matthew Gwiazdon, Arjun Rustagi, Jenelle Jindal, Jacob M. Koshy, Vinay Kadiyala, Anup Agarwal, Bassman Tappuni, Brianna French, Sirus Jesudasen, Christopher V. Cosgriff, Rebanta Chakraborty, Jillian Caldwell, Susan Ziolkowski, David J. Iberri, Robert Diep, Rahul S. Dalal, Kira L. Newman, Kristin Galetta, J. Carl Pallais, Nancy Wei, Kathleen M. Buchheit, David I. Hong, Vartan Pahalyants, Ernest Y. Lee, Allen Shih, Tamara B. Kaplan, Vishnu Ravi, Sarita Khemani, Thomas A. Buckley, April S. Liang, Daniel Shirvani, Advait Patil, Nicholas Marshall, Kanav Chopra, Joel Koh, Adi Badhwar, Anastasia Perez, Austin J. Schoeffler, Mahbuba Tusty, Chase M. Walton, Liam G. McCoy, David J. H. Wu, Yingjie Weng, Sumant Ranji, Kevin Schulman, Nigam H. Shah, Jason Hom, Arnold Milstein, Arjun K. Manrai, Adam Rodman, Jonathan H. Chen, Ethan Goh
arXiv:2609.14819v1 Announce Type: cross
Abstract: Large language models (LLMs) have a growing range of applications in medicine, and their evaluation is critical for ensuring they provide benefit and...
By Suzannah E McKinney, Phuc Vu, Samuel A Justice, Christopher Humphries, Alyssa Pradhan, Timothy J Keyes, Bernardo C Bizzo, Keith J Dreyer, Sarah F Mercaldo, James M Hillis
arXiv:2509. 21530v2 Announce Type: replace Abstract: Data augmentation is a widely used strategy to improve model robustness and generalization by enriching training datasets with synthetic examples.
By Dongkyu Cho, Miao Zhang, Rumi Chunara
Gaokerena is a family of compact Persian medical language models designed for consumer‑grade hardware. The first variant, Gaokerena‑V, was trained on a 90‑million‑token Persian medical corpus and 20,000 physician Q&A pairs, raising a translated medical MMLU benchmark score from 46.28% to 49.31%. A second variant, Gaokerena‑R, adds a Chain‑of‑Thought approach and two Reinforcement Learning with AI Feedback frameworks, achieving a higher benchmark score of 52.98% while also providing uncertainty estimates based on internal hidden states.
By Mehrdad Ghassabi, Hamidreza Baradaran Kashani, Pedram Rostami, Sadra Hakim, Zahra Kazemi, Amirhossein Poursina, Milad Tavakoli, Audrina Ebrahimi
arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.
By Yakun Zhu, Zhongzhen Huang, Linjie Mu, Yutong Huang, Wei Nie, Jiaji Liu, Shaoting Zhang, Pengfei Liu, Xiaofan Zhang
arXiv:2512.13742v3 Announce Type: replace-cross
Abstract: Medical image classifiers detect gastrointestinal diseases well, but they do not explain their decisions. Large language models can generate...
By Md. Najib Hasan (Wichita State University, USA), Imran Ahmad (Wichita State University, USA), Sourav Basak Shuvo (Khulna University of Engineering and Technology, Bangladesh), Md. Mahadi Hasan Ankon (Khulna University of Engineering and Technology, Bangladesh), Nazmul Siddique (Ulster University, UK), Hui Wang (Queen's University Belfast, UK)
arXiv:2605. 01189v2 Announce Type: replace Abstract: Clinical AI adoption is hindered by the black-box/grey-box nature of high-performing models, which lack the ontological grounding and narrative transparency required for professional-level explainability.
By Anuradha Chandrasekaran, Dimitrios Zikos, Mutlu Mete, Alan Pang, Brady D. Lund, Kewei Sha
arXiv:2608.23248v1 Announce Type: cross
Abstract: Traditional clinical prediction models rely on task-specific pipelines and curated, structured data, which scale poorly and underutilize unstructured...
By Siri Willems, James Butterworth, Lore Goetschalckx, Peter Vrancx, Philippe Modard, Elke Giets, Ludovic Denoyer
arXiv:2408. 02677v2 Announce Type: replace-cross Abstract: This study proposes a novel, integrative framework for patient-centered data science in the digital health era.
By Mohsen Amoei, Dan Poenaru
arXiv:2507. 02983v3 Announce Type: replace-cross Abstract: Large Language Models (LLMs) hold significant promise for transforming digital health by enabling automated medical question answering.
By Mohammad Anas Azeez, Rafiq Ali, Ebad Shabbir, Zohaib Hasan Siddiqui, Gautam Siddharth Kashyap, Jiechao Gao, Usman Naseem
arXiv:2606. 19183v1 Announce Type: cross Abstract: Large language models (LLMs) can make clinical decision support more accessible by interpreting free-text documentation, but their direct use as diagnostic engines is limited by sensitivity to prompts, information order, and plausible but incorrect outputs.
By Soheyl Bateni, Maryam Abdolali