arXiv:2610.33691v1 Announce Type: cross
Abstract: Whole Slide Image (WSI) analysis serves as the fundamental method for the clinical diagnosis of cancer in digital histopathology. Recent advances in...
By Nadun Rajapaksha, Sandun Herath, Devnith Wijesinghe, Isiri Amani Withanawasam, Hasindri Watawana, Ranga Rodrigo
The paper introduces a model‑agnostic framework that lets frozen large language models (LLMs) and vision‑language models (VLMs) learn from deployment experience without retraining. It does so by adding three external expertise components—a Skill for guiding reasoning and tool use, a Knowledge Memory for storing reliable facts, and a Multimodal Knowledge Base for visual examples—and by using a validation strategy that updates only when new cases improve performance without harming past performance. Experiments on six benchmarks with both open‑weight and closed‑source models show up to a 34.2% performance gain on medical tasks, generalization to unseen cases, and transferability to other models and non‑medical domains.
By Yexiao He, Yucheng Tang, Pengfei Guo, Yufan He, Andriy Myronenko, Can Zhao, Ang Li, Daguang Xu, Dong Yang
The paper introduces ThoughtMed-1M, a large-scale medical visual question answering dataset built from de‑identified images and clinician‑generated commentaries, designed to capture structured clinical reasoning and image‑text alignment. Using this dataset, the authors train FOLTMed, a foundational large language model that achieves state‑of‑the‑art performance on 42 medical VQA benchmarks, with a macro accuracy of 85.4% and improved factuality and similarity metrics over existing models.
By Lingxuan Hou, Yuhua Xie, Yue Hu, Yan Zhuang, Junqi Li, Chengzhi Xia, Binh Phu Nguyen, Abubakar Siddique, Minh Nguyen, Yao Hou, Yanju Bao, Kexin Liu, Ke Chen, Jianjun Sun, Zeqi Li, Trung Nguyen, Jiangli Lin
arXiv:2609.06914v1 Announce Type: new
Abstract: Large language models (LLMs) have demonstrated strong capabilities across diverse domains, showing considerable potential in medicine. However, their a...
By Lingxuan Hou, Yuhua Xie, Yue Hu, Yan Zhuang, Junqi Li, Chengzhi Xia, Binh Phu Nguyen, Abubakar Siddique, Minh Nguyen, Yao Hou, Yanju Bao, Kexin Liu, Ke Chen, Jianjun Sun, Zeqi Li, Trung Nguyen, Jiangli Lin
LiteMedCoT-VL is a parameter‑efficient pipeline that transfers chain‑of‑thought reasoning from a 235B teacher model to a 2B student model using LoRA fine‑tuning on explanation‑enriched data. The approach enables a compact vision‑language model to perform medical visual question answering without relying on image captions, achieving 64.9% accuracy on the PMC‑VQA benchmark—an 11‑point improvement over the zero‑shot Qwen3‑VL‑4B baseline. Visual grounding analysis confirms that the model bases its predictions on image content rather than textual priors.
By Runze Ma, Shunbo Jia, Haonan Lyu, Guo Liu, Caizhi Liao
arXiv:2606. 17958v1 Announce Type: cross Abstract: Semi-supervised medical image segmentation has emerged as a dominant research problem in medical image analysis, mitigating annotation scarcity by leveraging consistency regularization on unlabeled data.
By Yuming Chen, Yuxin Xie, Tao Zhou, Yi Zhou
arXiv:2610.08528v1 Announce Type: cross
Abstract: Clinical diagnosis is inherently a structured reasoning process, yet existing deep learning models often bypass this structure by mapping image featu...
By Asim Khan, Samee Ullah Khan, Dwarikanath Mahapatra
arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.
By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
The paper reviews how Large Language Models (LLMs) are being adapted for medical reasoning, moving beyond single-step answers to systems that can systematically, transparently, and verifiably reason. It introduces a taxonomy of enhancement techniques, split into training-time methods such as supervised fine‑tuning and reinforcement learning, and test-time methods like prompt engineering and multi‑agent systems. The review examines their application across text, image, and code modalities in key clinical areas—diagnosis, education, and treatment planning—and tracks the shift in evaluation benchmarks from simple accuracy to more nuanced assessments of reasoning quality and visual interpretability.
By Zizhan Ma, Wenxuan Wang, Meidan Ding, Shiyi Zheng, Shengyuan Liu, Jie Liu, Jiaming Ji, Linlin Shen, Yixuan Yuan, Wenting Chen
arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.
By Maria Xenochristou, Ashutosh Joshi, Korosh Vatanparvar, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Anchal Nema, Nivedita Wadhwa, Prashams S Jain, Rebecca Abraham, Will Kimbrough, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
arXiv:2607. 07761v1 Announce Type: new Abstract: Large language models (LLMs) have emerged as important tools in healthcare, showing growing potential for clinical reasoning and patient care.
By Qi Peng, Jiatong Li, Sirui Huang, Yiyang Jiang, Kaisong Gong, Ronger Ding, Shijie Ye, Changmeng Zheng, Yi Cai, Xiaobo Yang, Jin Huang, Xiao-Yong Wei, Qing Li
arXiv:2605. 22547v3 Announce Type: replace-cross Abstract: Medical image diagnosis has achieved significant progress with deep learning, yet existing methods often rely on isolated visual evidence and lack the ability to effectively leverage similar cases and external knowledge.
By Yiming Xu, Yixuan Liu, Yuhang Zhang, Ling Zheng, Yihan Wang, Qi Song