arXiv AI

Patient-centered data science: an integrative framework for evaluating and predicting clinical outcomes in the digital health era

arXiv:2408. 02677v2 Announce Type: replace-cross Abstract: This study proposes a novel, integrative framework for patient-centered data science in the digital health era.

arXiv AI
Jul 20

Cura 1T: Specialized Model for Agentic Healthcare

arXiv:2607. 15314v1 Announce Type: new Abstract: Healthcare spans high-stakes communication, expert reasoning, and workflow execution, yet specialized LLMs that cover these use cases together remain limited.

By actAVA AI, :, Haolin Chen, Leon Qi, Steve Brown, Deon Metelski, Tao Xia, Joonyul Lee, Qixuan Wang, Kevin Riley, Frank Wang, Weiran Yao
arXiv AI
Aug 25

MACD: Multi-Agent Clinical Diagnosis with Self-Learned Knowledge for LLM

The paper introduces MACD, a Multi-Agent Clinical Diagnosis framework that enables large language models to self‑learn clinical knowledge through a multi‑agent pipeline of summarization, refinement, and application. MACD is extended into a human‑AI collaborative workflow where multiple diagnostician agents consult iteratively, guided by a judge agent and human oversight. Evaluation on the MIMIC‑MACD cohort shows significant gains in diagnostic accuracy—an average 11.6 percentage‑point improvement over authoritative knowledge for open‑weight LLMs and an 18.3‑percentage‑point boost over physician‑only diagnosis in text‑only vignettes.

By Wenliang Li, Rui Yan, Xu Zhang, Li Chen, Hongji Zhu, Jing Zhao, Junjun Li, Mengru Li, Wei Cao, Zihang Jiang, Wei Wei, Kun Zhang, Shaohua Kevin Zhou
arXiv AI
Sep 15

LongAgent: History-Guided Agentic Search for Longitudinal Outcome Prediction

LongAgent is an agent-based method designed to extract predictive representations from heterogeneous longitudinal medical data. It autonomously searches over variable sets, temporal windows, and aggregation functions, using a history memory to guide exploration. On synthetic data, it achieves a mean prediction RMSE of 1.7376, outperforming the best non-agent baseline by 0.0151, and performs comparably to the best baseline on a real clinical dataset.

By Siyao Wang, Florian Guitton, Shuojie Fu, Guanyu Tao, Kai Sun, Wenjia Bai
arXiv AI
Jun 2

OpenHospital: A Thing-in-itself Arena for Evolving and Benchmarking LLM-based Collective Intelligence

arXiv:2603. 14771v3 Announce Type: replace Abstract: Large Language Model (LLM)-based Collective Intelligence (CI) presents a promising approach to overcoming the data wall and continuously boosting the capabilities of LLM agents.

By Peigen Liu, Rui Ding, Yuren Mao, Ziyan Jiang, Yuxiang Ye, Yunjun Gao, Ying Zhang, Renjie Sun, Longbin Lai, Zhengping Qian
arXiv AI
Jun 3

ChatHealthAI: Aligning Electronic Health Record Representations with Large Language Models for Grounded Clinical Reasoning

arXiv:2606. 02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs).

By Bo-Hong Wang, Baicheng Peng, Ruilin Wang, Jun Bai, Ziyang Song, Yue Li