arXiv:2608.22062v1 Announce Type: new
Abstract: Longitudinal clinical event-relation verification determines whether a patient record supports a specified relation among two or more clinical events....
By Xingtao Lin, Yubo Feng, Weixin Liu, Hangqi Ren, Junchao Zhou, Caiwan Sun, You Chen
CliniCIRCA is a modular large‑language‑model framework that reconstructs longitudinal mental‑health patient journeys from raw electronic health record narratives. It temporally classifies clinical events in unstructured discharge summaries without explicit timestamps, producing 15,891 tagged events from 52 summaries and correcting 629 errors to create verified gold‑standard timelines. The framework then generates temporally grounded summaries, compressing each source by 1.52×, and scales to produce 1,000 silver‑standard timelines for training, showing that instruction tuning improves event extraction, temporal tagging, and summarization across models.
By Aiwei Ivy Zhang, Nimra Ishfaq, Mohit Chandra, Santiago Alvarez Lesmes, Adam Coscia, Khatiya Chelidze Moon, Xiaohan Ding, Munmun De Choudhury
arXiv:2606. 05463v1 Announce Type: new Abstract: Patient safety event triage, determining whether a clinical event is reportable under jurisdiction-specific policy, is a high-stakes task typically performed manually by patient safety experts.
By Keqi Han, Ryan Young, Annabel Strauss, Lindsey Hughes, Katharine M. Nesbitt, Nicole Schueler, Che Ngufor, Carl Yang, Yuan Xue, Zhijun Yin
arXiv:2601.16753v2 Announce Type: replace-cross
Abstract: Longitudinal information in radiology reports refers to the sequential tracking of findings across multiple examinations over time, which is...
By Xinyi Wang, Grazziela Figueredo, Ruizhe Li, Xin Chen
arXiv:2608.28974v1 Announce Type: new
Abstract: Clinically relevant oncology information is distributed across heterogeneous, longitudinal documentation, creating substantial abstraction burden and r...
By Daniel Kang, Michelle Hu, Soorya Ram Shimgekar, Shayan Vassef, Yufan Wang, Anit Kumar Sahu, Munmun De Choudhury, Vedant Das Swain, Christian Poellabauer, Li Yan Khor, Koustuv Saha, Robert Wojciechowski, Elliot Kidd, Piyum Zonooz, Navin Kumar
The study evaluates large language models (LLMs) on unprocessed electronic medical record data for clinical registry abstraction, focusing on the American College of Cardiology National Cardiovascular Data Registry. In a pilot at one academic center, the LLM identified candidate data sources for each registry question, which abstractors used to define question‑specific document sets. In a subsequent validation at a second center, the LLM answered 157 registry questions with an overall mean accuracy of 91.5%, but accuracy dropped from 96% for simple medication or event flag questions to 62% for event timing questions, reflecting increasing ambiguity and required clinical reasoning.
By James Matheson, Betsy Castillo, Andrew Y. Shin, David Scheinker
Many operational cases are documented more than once, at different workflow stages and for different purposes, yet model evaluations normally select one of these records before model comparison begins...
arXiv:2608. 12779v1 Announce Type: cross Abstract: Understanding the temporal progression of symptoms in clinical narratives is critical for disease monitoring, safety surveillance, and causality assessment.
By Chengyang He, Tahreem Arif, Marko Zivkovic, Lijing Wang, Yue Ning, Ping Wang
arXiv:2609.16267v1 Announce Type: new
Abstract: Many operational cases are documented more than once, at different workflow stages and for different purposes, yet model evaluations normally select on...
By Hisham Ihshaish, Peter Mayhew, Tasnim M. A. Zayet, Ana Del Amo
Understanding the temporal progression of symptoms in clinical narratives is critical for disease monitoring, safety surveillance, and causality assessment. Clinical narratives, however, rarely provide explicit temporal anchors.
The paper introduces VERGE, a verification-enhanced refinement workflow that extracts six red‑flag symptoms and family‑history risk status for early‑onset colorectal cancer from free‑text clinical notes. VERGE uses retrieval‑augmented generation followed by a bounded verification‑refinement cycle that checks textual grounding and clinical validity, correcting claims until resolved or escalating to human review. In evaluation on 4,033 clinician‑labeled note‑finding pairs, VERGE improved precision from 0.764 to 0.849 and MCC from 0.681 to 0.730 compared to a single‑agent baseline, while requiring human review for only 1.5 % of claims.
By Nikkie Hooman, Monarch Nigam, Amy E. Hughes, Rasmi G. Nair, Mehak Gupta
The paper introduces Clinical Intent Extraction (CIE), a task that transforms fragmented clinical action annotations into complete structured records called Clinical Intent Representation (CIR). CIR decomposes each action into verb, type, coded target, timing, condition, request‑intent (aligned to HL7 FHIR) and modality, adding dimensions absent in prior datasets. By re‑expressing five heterogeneous corpora into CIR, the authors create CIRCA, a benchmark of 10,011 harmonized intents with human‑validated subsets, crosswalks, and a deterministic FHIR R4 mapper, and demonstrate that existing models perform poorly on the full task, highlighting the need for targeted development.
By Alexander Apartsin, Yehudit Aperstein