arXiv AI
ProCARE: Real-World Study Automation via Profile-Grounded Evidence Contracts
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arXiv AI
Aug 11
CliniCARE-Bench: Clinical Calibrated Audit of Medical Reasoning in EHR
arXiv:2608. 07796v1 Announce Type: new Abstract: Large language models perform strongly on medical knowledge benchmarks, but reliable clinical deployment requires agents to conduct defensible investigations over heterogeneous, longitudinal records: determining what evidence is needed, retrieving and reconciling structured and free-text data, grounding conclusions in verifiable evidence, and deferring cases that cannot be resolved reliably.
arXiv AI
Aug 26
EviDx: Evidence-Aware Active Diagnosis with Scaffolded LLM Agents
EviDx is a new framework for evidence-aware active diagnosis that pairs patient-specific diagnostic environments with a clinical scaffold and an observer-guided runtime harness. The framework constructs interactive environments from raw clinical cases, organizes role-specialized agents and evidence tools, and regulates diagnostic termination by tracking uncertainty and evidence coverage. Experiments demonstrate that EviDx improves diagnostic performance and process stability while revealing model-dependent capability boundaries.
arXiv AI
Jun 6
PSEBench: A Controllable and Verifiable Benchmark for Evaluating LLMs in Patient Safety Event Triage
arXiv:2606. 05463v1 Announce Type: new Abstract: Patient safety event triage, determining whether a clinical event is reportable under jurisdiction-specific policy, is a high-stakes task typically performed manually by patient safety experts.
arXiv AI
Sep 2
AI Morbidity and Mortality: A Framework for Clinical AI Failure Review
AI Morbidity and Mortality (AI M&M) is a structured, blameless framework designed to review clinical AI failures. It combines standardized case intake, evidence preservation, investigator reconstruction, tool‑in‑loop attribution, and corrective‑action tracking, classifying each event across four linked dimensions: Trigger, Mechanism, Clinical Pathway, and Corrective Action. The authors demonstrate the framework with five outpatient medication and clinical decision‑support cases, achieving full agreement among reviewers on all classification axes.
arXiv AI
Jun 30
MedCase-Structured: A Text-to-FHIR Dataset for Benchmarking Diagnostic Reasoning in Clinically Realistic EHR Settings
arXiv:2605. 30295v2 Announce Type: replace-cross Abstract: Large language models (LLMs) show promise for clinical reasoning and decision support, but evaluation in realistic, electronic health record-congruent settings remains limited.
arXiv AI
Sep 7
A Semantic Model of Genetic Evidence: A Step Toward Bridging the Basic-Science-Clinic Gap
The article presents a new semantic model for representing scientific evidence, specifically tailored to genetics, that extends existing standards by adding fine‑grained, domain‑specific structure. It aligns with FHIR Evidence and SEPIO, incorporates a compact vocabulary validated by SHACL, and was tested in a human‑AI annotation pilot on six genetics papers, producing 28 evidence items and 95 source‑anchored assertions. The authors argue that this model advances trustworthy, AI‑ready infrastructure for variant interpretation by providing a reference data model and validation schema for genetic evidence.