arXiv:2606. 09030v1 Announce Type: cross Abstract: Clinical early warning systems built on electronic health records, in which clinical observations are recorded as irregularly sampled medical time series (ISMTS), must deliver both calibrated risk scores for patient triage and interpretable rationales that clinicians can verify.
By Hyeongwon Jang, Gyouk Chu, Changhun Kim, Joonhyung Park, Hangyul Yoon, Eunho Yang
arXiv:2608. 12779v1 Announce Type: cross Abstract: Understanding the temporal progression of symptoms in clinical narratives is critical for disease monitoring, safety surveillance, and causality assessment.
By Chengyang He, Tahreem Arif, Marko Zivkovic, Lijing Wang, Yue Ning, Ping Wang
arXiv:2607. 08038v1 Announce Type: new Abstract: Diagnostic error is a major threat to patient safety, yet current large language model (LLM) systems often treat diagnosis as a one-shot prediction task, lacking safeguards against missed high-risk alternatives or rigorous verification of their reasoning.
By Fan Ma, Mauro Giuffr\`e, Donald Wright, Kent McCann, Mark Iscoe, Lingfei Qian, Mingyang Jiang, Chi Wing Ng, Na Hong, Huan He, Cathy Shyr, Qingyu Chen, Lee Schwamm, Lucila Ohno-Machado, Hua Xu
Understanding the temporal progression of symptoms in clinical narratives is critical for disease monitoring, safety surveillance, and causality assessment. Clinical narratives, however, rarely provide explicit temporal anchors.
arXiv:2602. 18446v2 Announce Type: replace-cross Abstract: Users increasingly rely on Large Language Models (LLMs) for Deep Research, using them to synthesize diverse sources into structured reports that support understanding and action.
By Jujia Zhao, Zhaoxin Huan, Zihan Wang, Xiaolu Zhang, Jun Zhou, Suzan Verberne, Zhaochun Ren
arXiv:2608. 07796v1 Announce Type: new Abstract: Large language models perform strongly on medical knowledge benchmarks, but reliable clinical deployment requires agents to conduct defensible investigations over heterogeneous, longitudinal records: determining what evidence is needed, retrieving and reconciling structured and free-text data, grounding conclusions in verifiable evidence, and deferring cases that cannot be resolved reliably.
By Veronica Chatrath, Bryan Zhu, George Pu, Jingxuan Fan, Apaar Shanker, Varun Ursekar, Anahita Sharma, Jason Qin, Keqi Han, Soham Dinesh Tiwari, Soham Dan, Vijay Kalmath, Yuan Li, Daniel Yue Zhang, Chenguang Wang, Zainab Doctor, Zhijun Yin, Nigam H. Shah, Yuan Xue
arXiv:2607. 04907v1 Announce Type: new Abstract: Deploying Large Language Models (LLMs) in high-stakes clinical settings remains limited by structural hallucinations, weak deterministic reasoning over tabular patient data, and omissions in vector retrieval.
By Mohammed Saim Ahmed Quadri, Yunzhe Xue, Justin W. Ady, Usman Roshan
arXiv:2409. 07314v3 Announce Type: replace-cross Abstract: While Large Language Models (LLMs) achieve superhuman performance on standardized medical licensing exams, these static benchmarks have become saturated and increasingly disconnected from the functional requirements of clinical workflows.
By Praveenkumar Kanithi, Cl\'ement Christophe, Marco AF Pimentel, Tathagata Raha, Prateek Munjal, Nada Saadi, Hamza A Javed, Svetlana Maslenkova, Nasir Hayat, Ronnie Rajan, Shadab Khan
arXiv:2607. 28677v1 Announce Type: new Abstract: LLM now pass medical licensing examinations and, in curated cases, can rival physicians at diagnostic reasoning.
By Shayndhan Sivanathan, Shravan Nageswaran, Mehdi Zadem, Ryaan Sultan, Nicolas von Mallinckrodt, Max Solovyev, Alexey Matyushkin, Sumon Sadhu, Gabriele C DeLuca, Sanjeeva Jeyaretna, James Hillis, Manoj Ramachandran, Prakash Jayakumar
arXiv:2607. 21307v1 Announce Type: cross Abstract: The reliance on unstructured free text for documenting clinical trial protocols creates a significant barrier to automated reasoning, cohort discovery, and trial simulation.
By Yan Huang, Xubing Hao, Xiaojin Li, Rashmie Abeysinghe, Xiaoqian Jiang, Licong Cui, Guo-Qiang Zhang
arXiv:2606. 19183v1 Announce Type: cross Abstract: Large language models (LLMs) can make clinical decision support more accessible by interpreting free-text documentation, but their direct use as diagnostic engines is limited by sensitivity to prompts, information order, and plausible but incorrect outputs.
By Soheyl Bateni, Maryam Abdolali
arXiv:2607. 28788v1 Announce Type: new Abstract: Clinical diagnosis at hospital admission must be made rapidly from limited, incomplete evidence.
By Jiahui Li, Ruili Fang, Zishuai Liu, Yutong Guo, Nan Yang, Wenzhan Song, Jin Lu, Fei Dou