arXiv Machine Learning

Explainability in mulimodal deep transformation models for stroke outcome prediction

arXiv:2504. 06299v2 Announce Type: replace-cross Abstract: Multimodal prediction models based on imaging and clinical data are increasingly used for clinical decision support, yet their interpretability remains limited.

arXiv Machine Learning
Jun 30

TRACE: A Concept Bottleneck Model for Longitudinal 3D Glioblastoma Response Assessment

arXiv:2606. 30313v1 Announce Type: cross Abstract: Longitudinal glioblastoma response assessment requires comparing subtle tumor changes across MRI time points using structured clinical criteria such as RANO.

By Alia Tarek, Hamsa Saberr, Hamza Elghonemy, Youssef Afify, Tamer Basha, Omair Shahzad Bhatti, Abdulrahman M. Selim, Hasan Md Tusfiqur Alam Daniel Sonntag
arXiv AI
Jun 17

Probing, Fusion, and Trustworthiness: A Systematic Evaluation of Foundation Model Representations for Multimodal Cancer Analysis

arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.

By Jingyu Hu, Giuseppe Tripodi, Reed Naidoo, Sarah F. McGough, Tapabrata Chakraborti
arXiv AI
Jun 12

BrainDINO: A Brain MRI Foundation Model for Generalizable Clinical Representation Learning

arXiv:2604. 27277v3 Announce Type: replace-cross Abstract: Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data.

By Yizhou Wu, Shansong Wang, Yuheng Li, Mojtaba Safari, Mingzhe Hu, Chih-Wei Chang, Harini Veeraraghavan, Xiaofeng Yang
arXiv AI
Jun 2

A Monosemantic Attribution Framework for Stable Interpretability in Clinical Neuroscience Transformer-Based Language Models

arXiv:2601. 17952v2 Announce Type: replace-cross Abstract: Interpretability remains a key challenge for deploying language models (LM) in clinical settings such as progression diagnosis of Alzheimer disease, where early and trustworthy predictions are essential.

By Michail Mamalakis, Tiago Azevedo, Cristian Cosentino, Chiara D'Ercoli, Subati Abulikemu, Zhongtian Sun, Richard Bethlehem, Pietro Lio
arXiv Machine Learning
Aug 10

Recovering Lesion Parameters from Aphasic Picture Naming Error Profiles in Large Language Models

arXiv:2608. 06429v1 Announce Type: cross Abstract: Interpretability methods for large language models (LLMs) describe internal state but do not directly test whether that state is causally sufficient to produce the observed behavior.

By Yong Yang, Roger Newman-Norlund, Xiang Guan, Saeed Ahmadi, Regan Willis, Nadra Salman, Kalil Warren, Sophie Arheix-Parras, Srihari Nelakuditi, Leonardo Bonilha, Christopher Rorden, Rutvik H. Desai, Julius Fridriksson
arXiv AI
Jun 9

Comparative evaluation of training strategies using partially labelled datasets for segmentation of white matter hyperintensities and stroke lesions in FLAIR MRI

arXiv:2601. 20503v2 Announce Type: replace-cross Abstract: White matter hyperintensities (WMH) and ischaemic stroke lesions (ISL) are key imaging biomarkers of cerebral small vessel disease (SVD) detectable on magnetic resonance imaging (MRI).

By Jesse Phitidis, Alison Q. Smithard, William N. Whiteley, Joanna M. Wardlaw, Miguel O. Bernabeu, Maria Vald\'es Hern\'andez
arXiv Machine Learning
Jul 22

Local Label-Informed Feature Transfer for Generating Ground-Truth Medical Images: A Comparison of GAN- and Diffusion-Based Approaches

arXiv:2607. 18882v1 Announce Type: cross Abstract: Validating Explainable Artificial Intelligence (XAI) methods in medical imaging requires ground-truth data with known locations of informative features.

By Rick Wilming, Irem Ozseker, Luca Matteo Cornils, Ahc\`ene Boubekki, Benedict Clark, Danny Panknin, Stefan Haufe
arXiv AI
5d ago

Mr3D-VL: A generalist vision language foundation model for Multiparametric 3D Magnetic Resonance Imaging

arXiv:2608. 12689v1 Announce Type: cross Abstract: Multi-parametric magnetic resonance imaging (mpMRI) is a cornerstone for brain tumor diagnosis and treatment, yet current AI models face critical limitations: their lack of natural language interaction and interpretability impedes spatial information integration and cross-modal reasoning required clinically.

By Zhi Qiao, Xintong Wu, Yichu He, Feng Shi