arXiv Machine Learning

Zero-Shot Active Feature Acquisition via LLM-Elicitation

arXiv:2606. 18933v1 Announce Type: new Abstract: Active feature acquisition (AFA) sequentially selects which features to observe to reach a classification or ranking decision.

arXiv AI
Jul 21

Retrieval-Augmented Interpretable Learning: Towards Task-Specific Zero-Shot Models in Healthcare

arXiv:2607. 17508v1 Announce Type: cross Abstract: We introduce Retrieval-Augmented Interpretable Learning (RAIL), a probabilistic meta-learning framework for zero-shot generation of task-specific interpretable models that synthesizes coefficient-space structure from natural-language task descriptions and a memory of previously learned task-specific predictors.

By Sazan Mahbub, Caleb Ellington, Zhiyuan Li, Yixin Yang, Souvik Kundu, Ben Lengerich, Eric P. Xing
arXiv AI
Jul 24

A Knowledge-Injection Framework for Zero-Shot Adaptation of LLMs to Delirium Prediction

arXiv:2607. 20453v1 Announce Type: cross Abstract: Large language models show promise for clinical prediction, but zero-shot performance on specialized tasks is limited by incomplete domain knowledge, especially for smaller locally deployable models.

By Jessica Sena, Shesadree Priyadarshani, Miguel Contreras, Bharat Gandhi, Scott Siegel, Subhash Nerella, Parisa Rashidi
arXiv Computation and Language
3d ago

Large Language Models are Approximate Survival Estimators

arXiv:2609.38181v1 Announce Type: new Abstract: Survival analysis estimates time-to-event outcomes from patient covariates and is widely used for medical risk assessment. Patients seeking prognostic...

By Juan M Zambrano Chaves, Peniel Argaw, Risa Ueno, Carlo Bifulco, Kristina Young, Rom Leidner, Tristan Naumann, Hoifung Poon
arXiv AI
Aug 13

Teaching agentic AI to learn expert reasoning for rare disease diagnosis

arXiv:2606. 16149v3 Announce Type: replace Abstract: Rare disease diagnosis depends on expert reasoning that is scarce and difficult to transfer; off-the-shelf large language models (LLMs) rank the correct disease first in only 35.

By Minh-Ha Nguyen, Erica Gray, Bryce A. Schuler, Kevin W. Byram, Chih-Ting Yang, Fan Ma, Hua Xu, Wu-Chen Su, Chao Yan, Wei-Qi Wei, Adam Wright, Lisa Bastarache, Josh Peterson, Lingyao Li, Siyuan Ma, Undiagnosed Diseases Network, Rizwan Hamid, Thomas A. Cassini, Cathy Shyr
arXiv Computation and Language
Sep 23

Learning Diagnostic Reasoning for Decision Support in Toxicology

The paper introduces DeToxR, a reinforcement‑learning‑enhanced large language model designed to support decision making in acute toxicology cases. It fuses unstructured narratives from paramedics and patients with structured vital‑sign data to predict co‑ingested substances across 14 classes. In preliminary validation, DeToxR outperforms baseline models, achieving higher micro‑F1 and recall scores for poison identification.

By Nico Oberl\"ander, David Bani-Harouni, Tobias Zellner, Nassir Navab, Florian Eyer, Matthias Keicher
arXiv AI
Sep 4

LLM4CKD: Large Language Models for Early Stage Chronic Kidney Disease Screening

The paper introduces LLM4CKD, a framework that uses large language models (LLMs) for early chronic kidney disease (CKD) screening without task‑specific training. By employing clinically selected tabular features and structured prompt templates, the authors evaluate LLMs in zero‑shot and few‑shot settings against traditional machine learning, deep learning, and tabular foundation models. Results show that LLMs can match or outperform conventional methods in low‑data scenarios, though their performance varies with model choice and input complexity, highlighting a trade‑off between data efficiency and stability.

By Muhammad Ashad Kabir, Sirajam Munira
arXiv AI
Jun 8

REMEDI: A Benchmark for Retention and Unlearning Evaluation in Multi-label Clinical Disease Inference

arXiv:2606. 07141v1 Announce Type: cross Abstract: Language models trained for clinical disease inference are trained on patient data, which may include sensitive and private information, and data owners may request the removal of their data from a trained model due to privacy or copyright concerns.

By Anurag Sharma, Sai Teja Chunchu, Prasenjit Mitra, Sandipan Sikdar, Koustav Rudra
arXiv Machine Learning
Jul 15

From Many to Meaningful: Feature-Guided Zero-Shot Chronic Kidney Disease Screening Using Large Language Models

arXiv:2607. 12260v1 Announce Type: new Abstract: Early screening of chronic kidney disease (CKD) is essential for preventing irreversible progression; however, many machine learning (ML)-based screening methods remain difficult to deploy in community and resource-limited screening settings due to their reliance on large labeled datasets, resource-intensive pathology tests, or high-dimensional clinical features, and limited robustness to population and distributional shifts.

By Muhammad Ashad Kabir, Sirajam Munira
arXiv Machine Learning
Aug 19

Pathology Transport: Optimal-Transport Explanations for Clinical Data, and When Their Heatmaps (Fail to) Localize Disease

The paper presents an optimal‑transport based generative model that learns the distributional differences between healthy and diseased patients, producing per‑patient counterfactuals and label‑free attribution heatmaps. On tabular breast cancer data the model achieves high malignancy scoring (AUROC ≈ 0.91) and its attributions correlate moderately with a supervised classifier, yet it does not surpass logistic regression. In chest X‑ray experiments the transport heatmaps capture population‑level signals but fail to localize real lesions, revealing a synthetic‑to‑real gap that challenges the reliability of label‑free explanations.

By Lalit Kumar
arXiv AI
Jun 24

SURGELLM: Rethinking Multi-Task Evaluation through Task-Aware Feature Gating with Class-Balanced Normalization

arXiv:2606. 24259v1 Announce Type: cross Abstract: Fine-tuned encoders deployed across heterogeneous NLP tasks face three compounding problems: mismatched inductive biases, class-imbalance corruption of feature statistics, and no mechanism to condition attention on external lexical knowledge.

By Noor Islam S. Mohammad, Ulug Bayazit