The paper introduces ANT, a test‑time adaptation framework that improves prostate cancer detection in micro‑ultrasound by performing a segmentation‑guided adaptation. ANT aligns a pretrained detection encoder to the target domain’s prostate anatomy using pseudo‑masks from a frozen segmentation network, thereby correcting domain‑specific feature drift while preserving cancer‑discriminative features. In a leave‑one‑center‑out evaluation, ANT raises mean AUC by 2.9% at the biopsy‑core level and 3.6% at the patient level compared to no adaptation, outperforming existing TTA baselines.
By Obed Korshie Dzikunu, Mohammad Mahdi Abootorabi, Mohamed Harmanani, Paul F. R. Wilson, Emma Willis, Ferdinand Luger, Adam Kinnaird, Brian Wodlinger, Parvin Mousavi, Purang Abolmaesumi
The paper introduces a Mixture of Multicenter Experts (MoME) framework that leverages diverse clinical strategies to reduce bias in medical AI without sharing data across institutions. MoME integrates specialized expertise from multiple centers, improving generalizability and adaptability of a multimodal target volume delineation model for prostate cancer radiotherapy. The model, trained with few-shot imaging and clinical notes, outperformed baselines, especially in high inter‑center variability or limited data scenarios, and allows local customization without cross‑institutional data exchange.
By Yujin Oh, Sangjoon Park, Xiang Li, Pengfei Jin, Yi Wang, Jonathan Paly, Jason Efstathiou, Annie Chan, Jun Won Kim, Hwa Kyung Byun, Ik Jae Lee, Jaeho Cho, Chan Woo Wee, Peng Shu, Peilong Wang, Caiwen Jiang, Nathan Yu, Jason Holmes, Jong Chul Ye, Quanzheng Li, Wei Liu, Woong Sub Koom, Jin Sung Kim, Kyungsang Kim
arXiv:2510. 17529v3 Announce Type: replace-cross Abstract: Active Surveillance (AS) is a treatment option for managing low and intermediate-risk prostate cancer (PCa), aiming to avoid overtreatment while monitoring disease progression through serial MRI and clinical follow-up.
By Yovin Yahathugoda, Davide Prezzi, Patricia A. Gutierrez, Piyalitt Ittichaiwong, Vicky Goh, Sebastien Ourselin, Michela Antonelli
Active surveillance (AS) is the preferred strategy for favorable-risk prostate cancer, yet current protocols rely on scheduled repeat biopsies, most of which reveal no progression and are unnecessary. Existing risk-stratification tools operate on single time-point imaging or depend on explicit lesion segmentation, limiting their ability to capture longitudinal change and excluding patients without an MRI-visible lesion.
arXiv:2606. 30951v1 Announce Type: cross Abstract: Micro-ultrasound ($\mu$US) is a new, emerging, and promising imaging modality for prostate cancer (PCa) detection, but accurate identification of suspicious tissue remains highly dependent on clinical experience, leading to substantial inter-observer variability.
By Mohammad Mahdi Abootorabi, Sina Namazi, Armin Saadat, Lyuyang Wang, Obed Dzikunu, Paul F. R. Wilson, Zhuoxin Guo, Brian Wodlinger, Parvin Mousavi, Purang Abolmaesumi
arXiv:2606. 19174v1 Announce Type: cross Abstract: Clinician-centered evaluation is critical for validating medical AI systems, especially in ultrasound imaging where quantitative metrics do not always capture clinical usability.
By Fangyijie Wang, Jianjun Yu, Wentao Shi, Haixia Huang, Ran Shi, Gu\'enol\'e Silvestre, Kathleen M. Curran
OncoVision is a privileged‑information training framework that learns from mammography images and clinical data during training but performs inference using only mammographic images. It employs an attention‑based encoder‑decoder to jointly segment masses, calcifications, axillary findings, and breast tissue, and predicts ten structured clinical features such as BI‑RADS. Two late‑fusion strategies (Independent and Dependent) integrate imaging, radiomic, and clinical information to improve diagnostic precision, and a retrospective multi‑reader study showed higher diagnostic confidence, reduced reading time, and segmentation accuracy comparable to or better than radiologists.
By Istiak Ahmed, Galib Ahmed, K. Shahriar Sanjid, Md. Tanzim Hossain, Md. Nishan Khan, Md. Misbah Khan, Md. Arifur Rahman, Sheikh Anisul Haque, Sharmin Akhtar Rupa, Mohammed Mejbahuddin Mia, Mahmud Hasan Mostofa Kamal, Md. Mostafa Kamal Sarker, M. Monir Uddin
arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.
By Maria Xenochristou, Ashutosh Joshi, Korosh Vatanparvar, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Anchal Nema, Nivedita Wadhwa, Prashams S Jain, Rebecca Abraham, Will Kimbrough, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
MultiViewDx is a physician‑validated multimodal instruction dataset that links medical imaging studies with patient context and normalizes heterogeneous reports into an evidence‑linked workflow (evidence → findings → differential discussion → diagnosis). The dataset covers a wide range of imaging modalities and uses a unified image‑text retriever to ensure that instruction synthesis is grounded in source‑supported evidence. Fine‑tuned models on MultiViewDx achieve the highest average accuracy on four MedVQA benchmarks and receive the strongest overall rating on JAMA Clinical Challenge cases, with ablations confirming the importance of case‑level multi‑view organization and evidence‑linked reasoning.
By Junda Wang, Zonghai Yao, Yujan Ting, Eric Z. Chen, Hieu Tran, Hong Yu, Weijing Huang, Terrence Chen
arXiv:2608. 14796v1 Announce Type: cross Abstract: Prostate cancer claims a life every 80 seconds.
By Ayusha Abbas, Saram Abbas, Kabita Adhikari
arXiv:2606. 28164v1 Announce Type: cross Abstract: Echocardiography is the most widely used non-invasive cardiac imaging modality, providing essential information for cardiovascular diagnosis.
By Darya Taratynova, Ahmed Aly, Numan Saeed, Mohammad Yaqub
arXiv:2608.21497v1 Announce Type: cross
Abstract: Biochemical recurrence (BCR), defined as any detectable prostate-specific antigen level after prostatectomy with confirmatory elevation, is widely us...
By Robert N. Spaans, Catherine Chia, Tongjie Wang, Adam Kowalewski, Parandzem Khachatryan, Domingos Oliveira, Khrystyna Faryna, Jean-Paul A. van Basten, Geert Litjens, Nadieh Khalili