Active surveillance (AS) is the preferred strategy for favorable-risk prostate cancer, yet current protocols rely on scheduled repeat biopsies, most of which reveal no progression and are unnecessary. Existing risk-stratification tools operate on single time-point imaging or depend on explicit lesion segmentation, limiting their ability to capture longitudinal change and excluding patients without an MRI-visible lesion.
The paper introduces ANT, a test‑time adaptation framework that improves prostate cancer detection in micro‑ultrasound by performing a segmentation‑guided adaptation. ANT aligns a pretrained detection encoder to the target domain’s prostate anatomy using pseudo‑masks from a frozen segmentation network, thereby correcting domain‑specific feature drift while preserving cancer‑discriminative features. In a leave‑one‑center‑out evaluation, ANT raises mean AUC by 2.9% at the biopsy‑core level and 3.6% at the patient level compared to no adaptation, outperforming existing TTA baselines.
By Obed Korshie Dzikunu, Mohammad Mahdi Abootorabi, Mohamed Harmanani, Paul F. R. Wilson, Emma Willis, Ferdinand Luger, Adam Kinnaird, Brian Wodlinger, Parvin Mousavi, Purang Abolmaesumi
arXiv:2605. 23995v4 Announce Type: replace-cross Abstract: Self-supervised learning (SSL) is increasingly used in medical image analysis to reduce dependence on costly expert annotations by learning transferable representations from unlabeled data.
By Chathura Wimalasiri, Kishor Nandakishor, Marimuthu Palaniswami
arXiv:2510.14383v4 Announce Type: replace
Abstract: Accurate brain tumor segmentation is significant for clinical diagnosis and treatment but remains challenging due to tumor heterogeneity. Mamba-bas...
By Danish Ali, Ajmal Mian, Naveed Akhtar, Ghulam Mubashar Hassan
The paper investigates combining a domain‑specific self‑supervised task—voxel‑level brain age prediction—with a general task—image inpainting—to pretrain models for brain MRI segmentation. A multitask pretraining framework jointly optimizes both objectives, yielding representations that outperform single‑task pretraining and training from scratch on three segmentation benchmarks (multiple sclerosis lesions, ischemic stroke lesions, and cortical structures). The study demonstrates that integrating domain‑specific and general self‑supervised tasks benefits the development of generalizable neuroimaging foundation models.
By Tasneem Nasser, Susanne Schmid, Roberto Souza, Naser El-Sheimy
arXiv:2608. 19666v1 Announce Type: new Abstract: Deep learning-based whole-body PET-CT lesion segmentation can support cancer staging, treatment planning, and response assessment, but generalization is limited by scarce annotations and domain shifts.
By Bashirul Azam Biswas, Amartya Bhattacharya, Biratal Raj Wagle, Matthew E. Maeder, James B. Yu, Indrani Bhattacharya
The paper introduces MSM‑Seg, a dual‑memory segmentation framework for 3D multi‑modal brain tumor segmentation. It combines a modality‑and‑slice memory attention module to capture cross‑modal and spatial‑slice dependencies, a multi‑scale category‑agnostic prompt encoder for whole‑tumor guidance, and a modality‑adaptive fusion decoder to integrate complementary decoding information. Experiments on various MRI datasets show that MSM‑Seg surpasses state‑of‑the‑art methods for metastases and glioma tumor segmentation.
By Yuxiang Luo, Qing Xu, Hai Huang, Yuqi Ouyang, Xiangjian He, Zhen Chen, Wenting Duan, Jiebo Luo
arXiv:2607.12896v3 Announce Type: replace
Abstract: Medical image segmentation foundation models are expected to generalize across diverse clinical scenarios, yet existing universal methods remain fr...
By Yunzhou Li, Jiesi Hu, Yanwu Yang, Hanyang Peng, Chenfei Ye, Jianfeng Cao, Yixuan Yuan, Ting Ma
BrainIAC is a unified framework for 3D brain lesion segmentation that handles heterogeneous MRI modalities and adapts online during interactive segmentation. It combines a multi‑modal backbone trained with zero‑filling and random modality dropping, 3D interactive prompts that default to fully automatic predictions, and a two‑stage online adaptation guided by pseudo‑labels and a Click‑Centered Gaussian loss. Experiments on seven MRI datasets show that the components work synergistically, outperforming existing methods and generalizing to unseen modalities and pathologies.
By Wentian Xu, Anthony P Addison, Ziyun Liang, Harry Anthony, Guang Yang, Konstantinos Kamnitsas
arXiv:2607. 17782v1 Announce Type: cross Abstract: Foundation models pretrained using self-supervised learning have transformed computer vision by learning transferable representations from large-scale unlabeled data.
By Moona Mazher, Abdul Qayyum, Steven A. Niederer, Daniel C. Alexander
arXiv:2609.25850v1 Announce Type: new
Abstract: Deep learning performance generally improves with increasing training data, yet this scaling is fundamentally constrained by annotation cost in large-s...
By Xiaofei Du, Lei Zhang, Shuyu Yan, Manning Wang, Zhijian Song
arXiv:2610.00279v1 Announce Type: new
Abstract: The segmentation of anatomical structures in medical images and particularly in MRI scans, is essential for clinical diagnosis and monitoring disease p...
By Eirini Cholopoulou, Dimitrios E. Diamantis, Dimitris K. Iakovidis