arXiv Machine Learning

Learning Prostate Anatomy at Test Time for Cancer Detection in Micro-Ultrasound

The paper introduces ANT, a test‑time adaptation framework that improves prostate cancer detection in micro‑ultrasound by performing a segmentation‑guided adaptation. ANT aligns a pretrained detection encoder to the target domain’s prostate anatomy using pseudo‑masks from a frozen segmentation network, thereby correcting domain‑specific feature drift while preserving cancer‑discriminative features. In a leave‑one‑center‑out evaluation, ANT raises mean AUC by 2.9% at the biopsy‑core level and 3.6% at the patient level compared to no adaptation, outperforming existing TTA baselines.

arXiv AI
Jul 1

Learning Where to Look: A Reinforcement Learning Framework for Robust Micro-Ultrasound Prostate Cancer Detection

arXiv:2606. 30951v1 Announce Type: cross Abstract: Micro-ultrasound ($\mu$US) is a new, emerging, and promising imaging modality for prostate cancer (PCa) detection, but accurate identification of suspicious tissue remains highly dependent on clinical experience, leading to substantial inter-observer variability.

By Mohammad Mahdi Abootorabi, Sina Namazi, Armin Saadat, Lyuyang Wang, Obed Dzikunu, Paul F. R. Wilson, Zhuoxin Guo, Brian Wodlinger, Parvin Mousavi, Purang Abolmaesumi
arXiv AI
Aug 21

MambaX-Net: Dual-Input Mamba-Enhanced Cross-Attention Network for Longitudinal Prostate MRI Segmentation

arXiv:2510. 17529v3 Announce Type: replace-cross Abstract: Active Surveillance (AS) is a treatment option for managing low and intermediate-risk prostate cancer (PCa), aiming to avoid overtreatment while monitoring disease progression through serial MRI and clinical follow-up.

By Yovin Yahathugoda, Davide Prezzi, Patricia A. Gutierrez, Piyalitt Ittichaiwong, Vicky Goh, Sebastien Ourselin, Michela Antonelli
arXiv AI
Aug 25

SAS: Segment Anything Small for Ultrasound -- A Non-Generative Data Augmentation Technique for Robust Deep Learning in Ultrasound Imaging

The paper introduces Segment Anything Small (SAS), a data‑augmentation method that improves deep‑learning segmentation of small anatomical structures in ultrasound images. SAS uses two transformations: resizing and embedding organ thumbnails into a black background to vary organ scale, and adding noise to regions of interest to mimic tissue texture variability. Experiments on one internal and five external datasets show Dice score gains up to 0.35, with an average improvement of 0.16, and demonstrate that SAS enhances model robustness and generalizability without adding hallucinations or artifacts.

By Danielle L. Ferreira, Ahana Gangopadhyay, Hsi-Ming Chang, Ravi Soni, Gopal Avinash
arXiv Machine Learning
Jul 9

Compass: Prostate Cancer Detection Needs Multi-View Context

arXiv:2607. 06919v1 Announce Type: cross Abstract: Artificial intelligence (AI) analysis of micro-ultrasound ($\mu$US) has shown promise for prostate cancer (PCa) detection.

By Paul F. R. Wilson, Mohamed Harmanani, Zhuoxin Guo, Obed K. Dzikunu, Hannes Cash, Adam Kinnaird, Brian Wodlinger, Purang Abolmaesumi, Parvin Mousavi
arXiv Computer Vision
Sep 15

Weakly Supervised Spatial Grounding for Discriminative Attention-Based Ultrasound-Histopathology Alignment in Prostate Cancer Grading

arXiv:2609.15150v1 Announce Type: new Abstract: Unpaired cross-modal distillation transfers grade structure from histopathology into a micro-ultrasound (micro-US) encoder by aligning a pooled needle-...

By Obed Korshie Dzikunu, Emma Willis, Mohammad Mahdi Abootorabi, Mohamed Harmanani, Zhuoxin Guo, Ferdinand Luger, Adam Kinnaird, Brian Wodlinger, Parvin Mousavi, Purang Abolmaesumi
arXiv AI
Jun 3

Anatomy-Anchored Self-Supervision: Distilling Vision Foundation Models for Invariant Ultrasound Representation

arXiv:2605. 25402v2 Announce Type: replace-cross Abstract: Self-supervised pre-training paradigm has gained increasing prominence for learning transferable representations in medical imaging, yet existing methods for ultrasound (US) images operate at the image or frame level, overlooking the anatomical context for clinical-aligned representation learning.

By Chunzheng Zhu, Yijun Wang, Jianxin Lin, Feng Wang, Hongwei Wang, Lei Zhao, Shengli Li, Kenli Li
Hugging Face Trending Papers
Jul 9

ProsMAE: Multi-Source MAE Pretraining for ISUP Grade Classification

Whole slide images (WSIs) provide rich diagnostic information for computational pathology, but their gigapixel scale, stain variation, scanner differences, tissue artifacts, and limited expert annotation make robust model training challenging. This paper presents a multi-source Masked Autoencoder (MAE) framework, named ProsMAE, for histopathology representation learning.

arXiv Computer Vision
Sep 30

PCaPaint: Prostate Cancer Inpainting by Mitigating Shortcut Learning

PCaPaint is a prostate cancer inpainting method that uses latent diffusion models (LDMs) and introduces a conditioning strategy where the condition image is filled with Gaussian noise to mitigate shortcut learning. It also proposes a new training objective that focuses on errors within the lesion region and a multi‑sequence latent design that separately compresses T2w and DWI&ADC scans to preserve their distinct frequency characteristics. Experiments show that the synthetic data generated by PCaPaint improves downstream tasks such as prostate lesion segmentation, patient‑level classification, and lesion‑level detection, outperforming recent state‑of‑the‑art LDM‑based tumor inpainting methods in both performance and image quality.

By Levente Lippenszky, Hongxu Yang, Marcell D\"om\"ot\"or, Krisztian Koos, L\'aszl\'o Rusk\'o
arXiv AI
Jul 10

ProsMAE: Multi-Source MAE Pretraining for ISUP Grade Classification

arXiv:2607. 08162v1 Announce Type: cross Abstract: Whole slide images (WSIs) provide rich diagnostic information for computational pathology, but their gigapixel scale, stain variation, scanner differences, tissue artifacts, and limited expert annotation make robust model training challenging.

By Anna Jung, Kyeonghun Kim, Youngung Han, Eunseob Choi, Jiwon Yang, Ken Ying-Kai Liao, Hyuk-Jae Lee, Nam-Joon Kim